Histone acetyltransferase activity of MOF is required for adult but not early fetal hematopoiesis in mice

scientific article published on 8 November 2016

Histone acetyltransferase activity of MOF is required for adult but not early fetal hematopoiesis in mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1182/BLOOD-2016-05-714568
P932PMC publication ID5216264
P698PubMed publication ID27827827

P2093author name stringTej K Pandita
Scott A Armstrong
Haiming Xu
Carolien M Woolthuis
Daria G Valerio
Meghan E Eisold
P2860cites workPhysical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOFQ24305335
Involvement of human MOF in ATM functionQ24529072
hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cellsQ24529984
A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16Q24534923
MOZ and MORF, two large MYSTic HATs in normal and cancer stem cellsQ24570117
ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESISQ24629431
The Role of Histone Acetyltransferases in Normal and Malignant HematopoiesisQ28088295
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cellsQ28201183
Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cellsQ28513079
Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexesQ28535100
The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryoQ28584885
Hematopoietic, angiogenic and eye defects in Meis1 mutant animalsQ28593369
New nomenclature for chromatin-modifying enzymesQ29616425
A molecular profile of a hematopoietic stem cell nicheQ30847561
MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele.Q33694927
MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repairQ33963853
The role of MOF in the ionizing radiation response is conserved in Drosophila melanogasterQ34119169
Roles of spleen and liver in development of the murine hematopoietic systemQ34149077
A stem cell molecular signatureQ34149366
The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis.Q34200216
Mouse embryonic hematopoiesisQ34289044
Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewalQ34379557
The journey of developing hematopoietic stem cellsQ34652843
30 nm chromatin fibre decompaction requires both H4-K16 acetylation and linker histone evictionQ34800325
Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defectQ35052404
In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cellsQ35066876
Breaking the histone code with quantitative mass spectrometry.Q35645008
Genetic programs regulating HSC specification, maintenance and expansionQ35892093
MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.Q35898171
Bone-marrow haematopoietic-stem-cell nichesQ36402226
The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesisQ36421093
Transcriptional activators, repressors, and epigenetic modifiers controlling hematopoietic stem cell developmentQ36426330
T-cell-specific deletion of Mof blocks their differentiation and results in genomic instability in miceQ36778963
Mof (MYST1 or KAT8) is essential for progression of embryonic development past the blastocyst stage and required for normal chromatin architecture.Q36845983
Genome-wide distribution of histone H4 Lysine 16 acetylation sites and their relationship to gene expressionQ36885484
MOF maintains transcriptional programs regulating cellular stress response.Q36970331
MYST family histone acetyltransferases take center stage in stem cells and development.Q37590236
The MYSTerious MOZ, a histone acetyltransferase with a key role in haematopoiesisQ38076474
A functional c-myb gene is required for normal murine fetal hepatic hematopoiesisQ38335144
A network of epigenetic regulators guides developmental haematopoiesis in vivoQ38364231
MOF phosphorylation by ATM regulates 53BP1-mediated double-strand break repair pathway choice.Q38982264
GCN5 and BCR signalling collaborate to induce pre-mature B cell apoptosis through depletion of ICAD and IAP2 and activation of caspase activitiesQ39974158
Unique and independent roles for MLL in adult hematopoietic stem cells and progenitorsQ39997748
A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cellsQ41175024
Polycomb group gene rae28 is required for sustaining activity of hematopoietic stem cellsQ41836764
The histone methyltransferase activity of MLL1 is dispensable for hematopoiesis and leukemogenesisQ42144295
The histone acetyltransferase MOF is a key regulator of the embryonic stem cell core transcriptional networkQ42264246
MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1.Q42375517
c-Myb and p300 regulate hematopoietic stem cell proliferation and differentiationQ43648204
Definitive hematopoiesis requires the mixed-lineage leukemia geneQ44805187
Defective long-term repopulating ability in hematopoietic stem cells lacking the Polycomb-group gene rae28.Q47221208
Assessing the role of hematopoietic plasticity for endothelial and hepatocyte development by non-invasive lineage tracing.Q52085270
Activation of transcription through histone H4 acetylation by MOF, an acetyltransferase essential for dosage compensation in Drosophila.Q52580421
Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells.Q54341375
P433issue1
P407language of work or nameEnglishQ1860
P921main subjecthemopoiesisQ919283
P304page(s)48-59
P577publication date2016-11-08
P1433published inBloodQ885070
P1476titleHistone acetyltransferase activity of MOF is required for adult but not early fetal hematopoiesis in mice
P478volume129

Reverse relations

cites work (P2860)
Q89515342Aging-associated decrease in the histone acetyltransferase KAT6B is linked to altered hematopoietic stem cell differentiation
Q64921703Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment.
Q60953054Emerging Role of Histone Acetyltransferase in Stem Cells and Cancer
Q90359201Isoform-specific involvement of Brpf1 in expansion of adult hematopoietic stem and progenitor cells
Q97528039Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate

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