Glutamine prevents fibrosis development in rats with colitis induced by 2,4,6-trinitrobenzene sulfonic acid.

scientific article published on 21 April 2010

Glutamine prevents fibrosis development in rats with colitis induced by 2,4,6-trinitrobenzene sulfonic acid. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3945/JN.110.121525
P698PubMed publication ID20410082
P5875ResearchGate publication ID43247261

P50authorBeatriz San-MiguelQ42576117
Irene CrespoQ42576119
María J. TuñónQ42576122
Javier González-GallegoQ42576129
José L. MaurizQ43778100
P2093author name stringNorma Marroni
Nelson A Kretzmann
P2860cites workIL-13 signaling via IL-13R alpha2 induces major downstream fibrogenic factors mediating fibrosis in chronic TNBS colitisQ46306807
Effects of glutamine on proinflammatory gene expression and activation of nuclear factor kappa B and signal transducers and activators of transcription in TNBS-induced colitisQ46486256
Prevention of colonic fibrosis by Boswellia and Scutellaria extracts in rats with colitis induced by 2,4,5-trinitrobenzene sulphonic acidQ46588301
TGF-beta and Smad3 signaling link inflammation to chronic fibrogenesisQ46740234
Matrix metalloproteinase-9 modulates intestinal injury in rats with transmural colitis.Q46945111
Chronic enteric salmonella infection in mice leads to severe and persistent intestinal fibrosisQ50063681
Targeting Smads to restore transforming growth factor-beta signaling and regulatory T-cell function in inflammatory bowel disease.Q51804523
Transforming growth factor beta signalling and matrix metalloproteinases in the mucosa overlying Crohn's disease strictures.Q51833572
Expression and regulation of connective tissue growth factor by transforming growth factor beta and tumour necrosis factor alpha in fibroblasts isolated from strictures in patients with Crohn's disease.Q54592387
N-acetyl-cysteine protects liver from apoptotic death in an animal model of fulminant hepatic failureQ59273528
Inflammatory Bowel DiseaseQ22248115
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel diseaseQ28346591
Glutamine inhibits over-expression of pro-inflammatory genes and down-regulates the nuclear factor kappaB pathway in an experimental model of colitis in the ratQ28575455
Regulative potential of glutamine--relation to glutathione metabolism.Q33957782
The immunological and genetic basis of inflammatory bowel diseaseQ34216426
Animal models of inflammatory bowel diseaseQ34728944
Impact of the increasing use of immunosuppressants in Crohn's disease on the need for intestinal surgeryQ35598052
Expression and regulation of tissue inhibitor of metalloproteinase-1 and matrix metalloproteinases by intestinal myofibroblasts in inflammatory bowel diseaseQ35749265
Smad7 in TGF-beta-mediated negative regulation of gut inflammationQ35885802
Fibrogenesis in Crohn's disease.Q36677634
Intestinal fibrosis in IBD--a dynamic, multifactorial processQ37433780
Potential for amino acids supplementation during inflammatory bowel diseasesQ37538650
CTGF promotes inflammatory cell infiltration of the renal interstitium by activating NF-kappaB.Q39855226
TGF-beta/Smad signaling defects in inflammatory bowel disease: mechanisms and possible novel therapies for chronic inflammationQ39947013
TNFalpha is required for cholestasis-induced liver fibrosis in the mouseQ41339503
The use of glutamine in the treatment of gastrointestinal disorders in man.Q41570323
Glutathione regulates transforming growth factor-beta-stimulated collagen production in fibroblastsQ42447194
Differential expression of TGF-beta isoforms by normal and inflammatory bowel disease intestinal myofibroblastsQ43822302
Tissue inhibitor of metalloproteinases-1 attenuates spontaneous liver fibrosis resolution in the transgenic mouseQ44151756
Intestinal subepithelial myofibroblasts in inflammatory bowel diseasesQ44305771
Platelet-derived growth factor and its receptors are expressed in areas of both active inflammation and active fibrosis in inflammatory bowel diseaseQ44627906
A murine model of chronic inflammation-induced intestinal fibrosis down-regulated by antisense NF-kappa B.Q44729219
Inflammation location, but not type, determines the increase in TGF-beta1 and IGF-1 expression and collagen deposition in IBD intestineQ44924237
Prevention of fibrosis in experimental colitis by captopril: the role of tgf-beta1.Q45096816
Prophylactic administration of topical glutamine enhances the capability of the rat colon to resist inflammatory damageQ45169713
Minocycline attenuates experimental colitis in mice by blocking expression of inducible nitric oxide synthase and matrix metalloproteinasesQ46088974
Smad3 loss confers resistance to the development of trinitrobenzene sulfonic acid-induced colorectal fibrosisQ46129986
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectcolitisQ2453464
P304page(s)1065-1071
P577publication date2010-04-21
P1433published inJournal of NutritionQ3186931
P1476titleGlutamine prevents fibrosis development in rats with colitis induced by 2,4,6-trinitrobenzene sulfonic acid.
P478volume140

Reverse relations

cites work (P2860)
Q39901570An integrated assessment of histopathological changes of the enteric neuromuscular compartment in experimental colitis.
Q82267860Beneficial effects of treatment with transglutaminase inhibitor cystamine on the severity of inflammation in a rat model of inflammatory bowel disease
Q36320785Dietary Protein and Amino Acid Supplementation in Inflammatory Bowel Disease Course: What Impact on the Colonic Mucosa?
Q34012514Effect of homocysteine on intestinal permeability in rats with experimental colitis, and its mechanism
Q33661327Glutamine supplementation attenuates expressions of adhesion molecules and chemokine receptors on T cells in a murine model of acute colitis
Q34500273Glutamine treatment attenuates endoplasmic reticulum stress and apoptosis in TNBS-induced colitis
Q35870335Histochemical Detection of Collagen Fibers by Sirius Red/Fast Green Is More Sensitive than van Gieson or Sirius Red Alone in Normal and Inflamed Rat Colon
Q54462926Homocysteine promotes intestinal fibrosis in rats with trinitrobenzene sulfonic acid-induced colitis.
Q28080664Matrix metalloproteinases in inflammatory bowel disease: an update
Q50445895Melatonin inhibits autophagy and endoplasmic reticulum stress in mice with carbon tetrachloride-induced fibrosis
Q50456374Melatonin limits the expression of profibrogenic genes and ameliorates the progression of hepatic fibrosis in mice.
Q46897362Preconditioning with glutamine protects against ischemia/reperfusion-induced hepatic injury in rats with obstructive jaundice
Q54364651Principal component analysis of mRNA levels of genes related to inflammation and fibrosis in rats treated with TNBS or glutamine.
Q37729852Protective Effect of Protocatechuic Acid on TNBS-Induced Colitis in Mice Is Associated with Modulation of the SphK/S1P Signaling Pathway
Q45031991Quercetin treatment ameliorates inflammation and fibrosis in mice with nonalcoholic steatohepatitis
Q41547434Sphingosine 1-Phosphate Signaling as a Target in Hepatic Fibrosis Therapy.
Q42368204Therapeutic Potential of Amino Acids in Inflammatory Bowel Disease
Q36215483Use of butyrate or glutamine in enema solution reduces inflammation and fibrosis in experimental diversion colitis.

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