scholarly article | Q13442814 |
P50 | author | Marta Ruiz-Ortega | Q56616783 |
Juan Rodriguez-Vita | Q58774280 | ||
Sandra Rayego-Mateos | Q59704892 | ||
Elsa Sanchez-Lopez | Q61162439 | ||
P2093 | author name string | Alberto Ortiz | |
Jesús Egido | |||
Raquel Rodrigues-Díez | |||
Rafael Selgas | |||
Sergio A Mezzano | |||
Luiz Stark Aroeira | |||
Gisselle Carvajal | |||
Javier Sánchez Rodriguez | |||
Raúl Rodrigues-Díez | |||
P2860 | cites work | Activation of nuclear factor kappa B (NF-kappaB) by connective tissue growth factor (CCN2) is involved in sustaining the survival of primary rat hepatic stellate cells | Q24815319 |
Tumor necrosis factor-alpha up-regulates the expression of CCL2 and adhesion molecules of human proximal tubular epithelial cells through MAPK signaling pathways | Q27863390 | ||
Connective tissue growth factor CCN2 interacts with and activates the tyrosine kinase receptor TrkA | Q28298502 | ||
IL-10 suppresses chemokines, inflammation, and fibrosis in a model of chronic renal disease | Q28574673 | ||
Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases | Q29547555 | ||
Connective tissue growth factor is overexpressed in complicated atherosclerotic plaques and induces mononuclear cell chemotaxis in vitro | Q33212781 | ||
Influence of connective tissue growth factor antisense oligonucleotide on angiotensin II-induced epithelial mesenchymal transition in HK2 cells | Q33251736 | ||
The CCN family of angiogenic regulators: the integrin connection | Q33545691 | ||
Connective tissue growth factor: potential role in glomerulosclerosis and tubulointerstitial fibrosis | Q34050059 | ||
Transcription factor-kappa B (NF-kappa B) and renal disease. | Q34135831 | ||
The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex. | Q34505685 | ||
Nuclear factor-kappa B inhibitors as potential novel anti-inflammatory agents for the treatment of immune glomerulonephritis | Q35789327 | ||
Angiotensin II increases connective tissue growth factor in the kidney. | Q35843514 | ||
Identification and characterization of a fibroblast marker: FSP1 | Q36382596 | ||
Connective tissue growth factor and susceptibility to renal and vascular disease risk in type 1 diabetes. | Q36661077 | ||
The role of chemokines and chemokine receptors in diabetic nephropathy | Q36991984 | ||
The phenotype of human Th17 cells and their precursors, the cytokines that mediate their differentiation and the role of Th17 cells in inflammation. | Q37280352 | ||
Induction, function and regulation of IL-17-producing T cells | Q37311131 | ||
Role of ERK1/2 and PI3-K in the regulation of CTGF-induced ILK expression in HK-2 cells | Q40133623 | ||
Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: implications for diabetic renal disease. | Q40242733 | ||
Nicotine enhances human vascular endothelial cell expression of ICAM-1 and VCAM-1 via protein kinase C, p38 mitogen-activated protein kinase, NF-kappaB, and AP-1. | Q40255157 | ||
Roles of PKC, PI3K and JNK in multiple transduction of CCN2/CTGF signals in chondrocytes | Q40326104 | ||
Reactive oxygen species-mediated signaling pathways in angiotensin II-induced MCP-1 expression of proximal tubular cells. | Q40382593 | ||
NF-kappaB mediated IL-6 production by renal epithelial cells is regulated by c-jun NH2-terminal kinase | Q40432734 | ||
Role of connective tissue growth factor in renal tubular epithelial-myofibroblast transdifferentiation and extracellular matrix accumulation in vitro | Q40557517 | ||
Interferon-gamma induces macrophage migration inhibitory factor synthesis and secretion by tubular epithelial cells. | Q40580288 | ||
CTGF/Hcs24 induces chondrocyte differentiation through a p38 mitogen-activated protein kinase (p38MAPK), and proliferation through a p44/42 MAPK/extracellular-signal regulated kinase (ERK). | Q40765291 | ||
p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor. | Q41062073 | ||
The role of p42/44 MAPK and protein kinase B in connective tissue growth factor induced extracellular matrix protein production, cell migration, and actin cytoskeletal rearrangement in human mesangial cells. | Q44129438 | ||
Plasma connective tissue growth factor is an independent predictor of end-stage renal disease and mortality in type 1 diabetic nephropathy | Q44617933 | ||
In vivo administration of a nuclear transcription factor-kappaB decoy suppresses experimental crescentic glomerulonephritis. | Q44688666 | ||
Angiotensin II, via AT1 and AT2 receptors and NF-kappaB pathway, regulates the inflammatory response in unilateral ureteral obstruction. | Q44903329 | ||
Endogenous interleukin-6 enhances the renal injury, dysfunction, and inflammation caused by ischemia/reperfusion | Q45168898 | ||
Molecular insights into connective tissue growth factor action in rat pancreatic stellate cells | Q46474579 | ||
Effect of silencing connective tissue growth factor on rat liver fibrosis and the accumulation of extracellular matrix | Q46684349 | ||
Plasma connective tissue growth factor is a novel potential biomarker of cardiac dysfunction in patients with chronic heart failure | Q46705065 | ||
Lipoxin A4 inhibits connective tissue growth factor-induced production of chemokines in rat mesangial cells | Q46891070 | ||
IL-4 and IL-13 augment cytokine- and CD40-induced RANTES production by human renal tubular epithelial cells in vitro | Q47917213 | ||
Renal expression of IL-6 and TNFalpha genes in lupus nephritis | Q48024829 | ||
Suppression of cell proliferation and signaling transduction by connective tissue growth factor in non-small cell lung cancer cells. | Q51153671 | ||
TGF-beta1 and CTGF mRNAs are correlated with urinary protein level in IgA nephropathy. | Q53499066 | ||
Cytokine balance in kidney tissue from lupus nephritis patients | Q53655942 | ||
Connective tissue growth factor is responsible for transforming growth factor-beta-induced peritoneal mesothelial cell apoptosis. | Q54606047 | ||
Connective Tissue Growth Factor Expressed in Tubular Epithelium Plays a Pivotal Role in Renal Fibrogenesis | Q57691320 | ||
Role of connective tissue growth factor in fibronectin expression and tubulointerstitial fibrosis | Q61648789 | ||
Inhibitory effect of interleukin-1β on angiotensin II-induced connective tissue growth factor and type IV collagen production in cultured mesangial cells | Q61854905 | ||
Angiotensin IV Activates the Nuclear Transcription Factor-κB and Related Proinflammatory Genes in Vascular Smooth Muscle Cells | Q61854944 | ||
Renal connective tissue growth factor correlates with glomerular basement membrane thickness and prospective albuminuria in a non-human primate model of diabetes: possible predictive marker for incipient diabetic nephropathy | Q62504236 | ||
Expression of interleukin 6 and major histocompatibility complex molecules in tubular epithelial cells of diseased human kidneys | Q72832749 | ||
Tubular epithelial cells: A critical cell type in the regulation of renal inflammatory processes | Q73177067 | ||
Endogenous interleukin-10 regulates Th1 responses that induce crescentic glomerulonephritis | Q73395940 | ||
Role of MCP-1 and RANTES in inflammation and progression to fibrosis during murine crescentic nephritis | Q73867315 | ||
Autocrine production of IFN-gamma by macrophages controls their recruitment to kidney and the development of glomerulonephritis in MRL/lpr mice | Q74410142 | ||
Tubular NF-kappaB and AP-1 activation in human proteinuric renal disease | Q74566827 | ||
Interleukin 4 co-stimulates the PDGF-BB- and bFGF-mediated proliferation of mesangial cells and myofibroblasts | Q78425901 | ||
Involvement of MAPKs and NF-kappaB in LPS-induced VCAM-1 expression in human tracheal smooth muscle cells | Q79781731 | ||
Inhibition of p38 mitogen-activated protein kinase is effective in the treatment of experimental crescentic glomerulonephritis and suppresses monocyte chemoattractant protein-1 but not IL-1beta or IL-6 | Q79808046 | ||
NF-kappaB activation and overexpression of regulated genes in human diabetic nephropathy | Q80389149 | ||
Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes | Q80441677 | ||
Connective tissue growth factor-specific antibody attenuates tumor growth, metastasis, and angiogenesis in an orthotopic mouse model of pancreatic cancer | Q83862044 | ||
Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis | Q95811801 | ||
P433 | issue | 7 | |
P921 | main subject | NF-κB | Q411114 |
inflammation | Q101991 | ||
P304 | page(s) | 1513-1526 | |
P577 | publication date | 2009-05-07 | |
P1433 | published in | Journal of the American Society of Nephrology | Q17123893 |
P1476 | title | CTGF promotes inflammatory cell infiltration of the renal interstitium by activating NF-kappaB | |
P478 | volume | 20 |
Q37786866 | An integrative overview on the mechanisms underlying the renal tubular cytotoxicity of gentamicin |
Q39529950 | Angiotensin II receptor type 1 blockade decreases CTGF/CCN2-mediated damage and fibrosis in normal and dystrophic skeletal muscles. |
Q33795658 | Anti-connective tissue growth factor (CTGF/CCN2) monoclonal antibody attenuates skin fibrosis in mice models of systemic sclerosis |
Q37635765 | CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and αVβ3 integrins in nucleus pulposus cells: implications in intervertebral disc degeneration |
Q26779818 | CCN: core regulatory proteins in the microenvironment that affect the metastasis of hepatocellular carcinoma? |
Q34720176 | CTGF disrupts alveolarization and induces pulmonary hypertension in neonatal mice: implication in the pathogenesis of severe bronchopulmonary dysplasia |
Q58798857 | CTGF in kidney fibrosis and glomerulonephritis |
Q39493006 | CTGF/CCN-2 over-expression can directly induce features of skeletal muscle dystrophy |
Q91998745 | Connective Tissue Growth Factor Is Related to All-cause Mortality in Hemodialysis Patients and Is Lowered by On-line Hemodiafiltration: Results from the Convective Transport Study |
Q42776466 | Connective Tissue Growth Factor Promotes Efficient Generation of Human Induced Pluripotent Stem Cell-Derived Choroidal Endothelium |
Q47379089 | Connective tissue growth factor induces renal fibrosis via epidermal growth factor receptor activation |
Q39007697 | Construction of a CTGF and RFP-coexpressed renal tubular epithelial cell and its application on evaluation of CTGF-specific siRNAs on epithelial-mesenchymal transition |
Q82547320 | Could aging human skin use a connective tissue growth factor boost to increase collagen content? |
Q37638074 | Crucial Role of Mesangial Cell-derived Connective Tissue Growth Factor in a Mouse Model of Anti-Glomerular Basement Membrane Glomerulonephritis. |
Q49808713 | Deletion of connective tissue growth factor ameliorates peritoneal fibrosis by inhibiting angiogenesis and inflammation |
Q37597721 | Diabetes-Induced Reactive Oxygen Species: Mechanism of Their Generation and Role in Renal Injury |
Q99572013 | DsbA-L mediated renal tubulointerstitial fibrosis in UUO mice |
Q38075029 | Emerging drugs for managing kidney disease in patients with diabetes. |
Q38806090 | Expression of connective tissue growth factor in the livers of non-viral hepatocellular carcinoma patients with metabolic risk factors. |
Q42202374 | Expression of heat shock protein 47, transforming growth factor-beta 1, and connective tissue growth factor in liver tissue of patients with Schistosoma japonicum-induced hepatic fibrosis |
Q43763309 | Fell-Muir lecture: Connective tissue growth factor (CCN2) -- a pernicious and pleiotropic player in the development of kidney fibrosis |
Q35184582 | Females uniquely vulnerable to alcohol-induced neurotoxicity show altered glucocorticoid signaling |
Q33622876 | Gingerol fraction from Zingiber officinale protects against gentamicin-induced nephrotoxicity |
Q50579974 | Glutamine prevents fibrosis development in rats with colitis induced by 2,4,6-trinitrobenzene sulfonic acid. |
Q28118491 | Interleukin-18/WNT1-inducible signaling pathway protein-1 signaling mediates human saphenous vein smooth muscle cell proliferation |
Q34566817 | Laser therapy in metabolic syndrome-related kidney injury |
Q36051055 | Locally expressed IGF1 propeptide improves mouse heart function in induced dilated cardiomyopathy by blocking myocardial fibrosis and SRF-dependent CTGF induction. |
Q41496919 | Mastering a mediator: blockade of CCN-2 shows early promise in human diabetic kidney disease |
Q85673592 | Maternal nicotine exposure during gestation and lactation induces kidney injury and fibrosis in rat offspring |
Q38062404 | Molecular targets for treatment of kidney fibrosis |
Q54420633 | Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation. |
Q48492207 | Plasma CTGF is independently related to an increased risk of cardiovascular events and mortality in patients with atherosclerotic disease: the SMART study |
Q26784039 | Potential Renoprotective Agents through Inhibiting CTGF/CCN2 in Diabetic Nephropathy |
Q39002130 | Regulation of pancreatic inflammation by connective tissue growth factor (CTGF/CCN2). |
Q41988029 | Regulation of pro-inflammatory and pro-fibrotic factors by CCN2/CTGF in H9c2 cardiomyocytes. |
Q40155862 | Role of ESAT-6 in renal injury by regulating microRNA-155 expression via TLR4/MyD88 signaling pathway in mice with Mycobacterium tuberculosis infection |
Q60935640 | Role of Epidermal Growth Factor Receptor (EGFR) and Its Ligands in Kidney Inflammation and Damage |
Q26995820 | Splanchnic-aortic inflammatory axis in experimental portal hypertension |
Q40812992 | TGF-Beta Blockade Increases Renal Inflammation Caused by the C-Terminal Module of the CCN2. |
Q28254386 | Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets |
Q104568869 | Targeting CTGF in Cancer: An Emerging Therapeutic Opportunity |
Q38259755 | Targeting CTGF, EGF and PDGF pathways to prevent progression of kidney disease. |
Q89723568 | Targeting the progression of chronic kidney disease |
Q51016267 | The C-terminal module IV of connective tissue growth factor is a novel immune modulator of the Th17 response. |
Q42876722 | The C-terminal module IV of connective tissue growth factor, through EGFR/Nox1 signaling, activates the NF-κB pathway and proinflammatory factors in vascular smooth muscle cells. |
Q90102312 | The Role of CTGF in Inflammatory Responses Induced by Silica Particles in Human Bronchial Epithelial Cells |
Q37683183 | The Small Tellurium Compound AS101 Ameliorates Rat Crescentic Glomerulonephritis: Association with Inhibition of Macrophage Caspase-1 Activity via Very Late Antigen-4 Inactivation |
Q37427986 | The coordinated roles of miR-26a and miR-30c in regulating TGFβ1-induced epithelial-to-mesenchymal transition in diabetic nephropathy |
Q64248028 | The expression profile analysis of atrial mRNA in rats with atrial fibrillation: the role of IGF1 in atrial fibrosis |
Q45189914 | The matri-cellular proteins 'cysteine-rich, angiogenic-inducer, 61' and 'connective tissue growth factor' are regulated in experimentally-induced sepsis with multiple organ dysfunction |
Q48100107 | The pro-fibrotic connective tissue growth factor (CTGF/CCN2) correlates with the number of necrotic-regenerative foci in dystrophic muscle |
Q48223429 | The role of NFκB in spheroid formation of human breast cancer cells cultured on the Random Positioning Machine. |
Q87207661 | Tubastatin A suppresses renal fibrosis via regulation of epigenetic histone modification and Smad3-dependent fibrotic genes |
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