The claudin-16 channel gene is transcriptionally inhibited by 1,25-dihydroxyvitamin D.

scientific article published on 2 December 2014

The claudin-16 channel gene is transcriptionally inhibited by 1,25-dihydroxyvitamin D. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1113/EXPPHYSIOL.2014.083394
P698PubMed publication ID25557732

P2093author name stringIsrael Zelikovic
Edna Efrati
Hilla Azulay-Debby
Julia Rozenfeld
Orly Kladnitsky
P2860cites workEnhancement of ligand-dependent vitamin D receptor transactivation by the cardiotonic steroid bufalinQ40369259
Transrepression by a liganded nuclear receptor via a bHLH activator through co-regulator switchingQ40413870
The human paracellin-1 gene (hPCLN-1): renal epithelial cell-specific expression and regulationQ40518120
Aminoglycosides increase intracellular calcium levels and ERK activity in proximal tubular OK cells expressing the extracellular calcium-sensing receptorQ40728268
Renal magnesium handling: new insights in understanding old problemsQ40879258
A negative vitamin D response DNA element in the human parathyroid hormone-related peptide gene binds to vitamin D receptor along with Ku antigen to mediate negative gene regulation by vitamin D.Q41036961
All natural DR3-type vitamin D response elements show a similar functionality in vitroQ42131666
Increased NF-kappaB activity in fibroblasts lacking the vitamin D receptorQ42491472
Human calcium-sensing receptor gene. Vitamin D response elements in promoters P1 and P2 confer transcriptional responsiveness to 1,25-dihydroxyvitamin D.Q42521852
Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes.Q42985802
Calcification is associated with loss of functional calcium-sensing receptor in vascular smooth muscle cellsQ45002024
1,25-dihydroxyvitamin D(3) rapidly stimulates the solvent drag-induced paracellular calcium transport in the duodenum of female ratsQ46329683
Regulation of renal calcium receptor gene expression by 1,25-dihydroxyvitamin D3 in genetic hypercalciuric stone-forming ratsQ46402334
The epithelial Mg2+ channel transient receptor potential melastatin 6 is regulated by dietary Mg2+ content and estrogensQ46981321
Claudin multigene family encoding four-transmembrane domain protein components of tight junction strandsQ22008687
Paracellin-1, a renal tight junction protein required for paracellular Mg2+ resorptionQ22010191
Claudin-14 regulates renal Ca⁺⁺ transport in response to CaSR signalling via a novel microRNA pathwayQ24306467
Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvementQ24672137
Vitamin D.Q27919675
Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene familyQ28200813
TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorptionQ28212198
Expression and characterization of inactivating and activating mutations in the human Ca2+o-sensing receptorQ29465783
Physiology and pathophysiology of the calcium-sensing receptor in the kidneyQ33727776
Paracellin-1 and the modulation of ion selectivity of tight junctionsQ34460832
Claudins and the modulation of tight junction permeabilityQ34650517
Renal physiology of the extracellular calcium-sensing receptorQ35011731
New insights into the mechanisms of vitamin D actionQ35063585
Regulation of cell magnesiumQ35831400
The pendrin anion exchanger gene is transcriptionally regulated by uroguanylin: a novel enterorenal linkQ35964499
PTH-independent regulation of blood calcium concentration by the calcium-sensing receptorQ36190666
Deficiency of the calcium-sensing receptor in the kidney causes parathyroid hormone-independent hypocalciuriaQ36352175
Mechanisms of transcriptional repression by 1,25(OH)2 vitamin D.Q36848096
Activation of the Ca(2+)-sensing receptor increases renal claudin-14 expression and urinary Ca(2+) excretion.Q37123850
The full-length calcium-sensing receptor dampens the calcemic response to 1alpha,25(OH)2 vitamin D3 in vivo independently of parathyroid hormoneQ37337334
The calcium-sensing receptor (CaSR) defends against hypercalcemia independently of its regulation of parathyroid hormone secretionQ37391736
Novel Ca receptor signaling pathways for control of renal ion transportQ37613414
Claudin-14 underlies Ca⁺⁺-sensing receptor-mediated Ca⁺⁺ metabolism via NFAT-microRNA-based mechanismsQ37670320
The calcium-sensing receptor beyond extracellular calcium homeostasis: conception, development, adult physiology, and disease.Q37948077
Transcriptional regulation of the claudin-16 gene by Mg2+ availabilityQ39698636
Claudin-16 affects transcellular Cl- secretion in MDCK cellsQ39837634
Vitamin D receptor: key roles in bone mineral pathophysiology, molecular mechanism of action, and novel nutritional ligandsQ40001200
Activation of a polyvalent cation-sensing receptor decreases magnesium transport via claudin-16.Q40058720
Renal localization and function of the tight junction protein, claudin-19.Q40153685
Termination of cAMP signals by Ca2+ and G(alpha)i via extracellular Ca2+ sensors: a link to intracellular Ca2+ oscillationsQ40358368
P433issue1
P304page(s)79-94
P577publication date2014-12-02
P1433published inExperimental PhysiologyQ1091760
P1476titleThe claudin-16 channel gene is transcriptionally inhibited by 1,25-dihydroxyvitamin D.
P478volume100

Reverse relations

cites work (P2860)
Q36963620Claudins and mineral metabolism
Q47214679Magnesium homeostasis in cattle: absorption and excretion
Q51315381Omeprazole suppressed plasma magnesium level and duodenal magnesium absorption in male Sprague-Dawley rats.
Q41386008Vitamin D supplementation of initially vitamin D-deficient mice diminishes lung inflammation with limited effects on pulmonary epithelial integrity.

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