The Histone Variant MacroH2A1 Is a BRCA1 Ubiquitin Ligase Substrate

scientific article published in May 2017

The Histone Variant MacroH2A1 Is a BRCA1 Ubiquitin Ligase Substrate is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELREP.2017.05.027
P932PMC publication ID6507409
P698PubMed publication ID28564596

P2093author name stringYi Wang
Yue Chen
Jun Qin
Sung Yun Jung
Beom-Jun Kim
Doug W Chan
P2860cites workE2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkagesQ24293777
Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligaseQ24295278
CR6-interacting factor 1 interacts with Gadd45 family proteins and modulates the cell cycleQ24300586
Role of histone H2A ubiquitination in Polycomb silencingQ24305090
Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entitiesQ24320127
Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1bQ24337331
Systematic and quantitative assessment of the ubiquitin-modified proteomeQ24634631
A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiencyQ28256846
SHPRH and HLTF Act in a Damage-Specific Manner to Coordinate Different Forms of Postreplication Repair and Prevent MutagenesisQ29871514
Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling.Q29871515
A data set of human endogenous protein ubiquitination sitesQ33726799
Genome-wide reinforcement of cohesin binding at pre-existing cohesin sites in response to ionizing radiation in human cellsQ34003794
A macrohistone variant links dynamic chromatin compaction to BRCA1-dependent genome maintenance.Q34132182
Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profilingQ34159143
BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIPQ34863348
A comprehensive method for detecting ubiquitinated substrates using TR-TUBE.Q35485052
BRCA1 tumour suppression occurs via heterochromatin-mediated silencing.Q35618582
Estrogen receptor alpha is a putative substrate for the BRCA1 ubiquitin ligaseQ35749504
Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence.Q35819035
Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoformQ35963880
MacroH2A1 and ATM Play Opposing Roles in Paracrine Senescence and the Senescence-Associated Secretory PhenotypeQ35994479
Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.Q36163471
Understanding cullin-RING E3 biology through proteomics-based substrate identificationQ36455676
BRG1 is required for formation of senescence-associated heterochromatin foci induced by oncogenic RAS or BRCA1 lossQ36759676
BRCA1 and its toolbox for the maintenance of genome integrityQ37507563
Multiple facets of the unique histone variant macroH2A: from genomics to cell biologyQ37764645
The BRCA1 ubiquitin ligase and homologous recombination repairQ37875478
BRCA1 is a histone-H2A-specific ubiquitin ligaseQ43212891
Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivoQ43221614
P433issue9
P304page(s)1758-1766
P577publication date2017-05-01
P1433published inCell ReportsQ5058165
P1476titleThe Histone Variant MacroH2A1 Is a BRCA1 Ubiquitin Ligase Substrate
P478volume19

Reverse relations

cites work (P2860)
Q48172154BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes.
Q60954599BRCA1-Dependent Transcriptional Regulation: Implication in Tissue-Specific Tumor Suppression
Q93133542CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity
Q95324882Histone H2A variants alpha1-extension helix directs RNF168-mediated ubiquitination
Q53827263Post-Translational Modifications of H2A Histone Variants and Their Role in Cancer.
Q49713141Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions
Q89866885The antitumorigenic roles of BRCA1-BARD1 in DNA repair and replication

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