Molecular epigenetic approach activates silent gene cluster producing dimeric bis-spiro-azaphilones in Chaetomium globosum CBS148.51.

scientific article published in March 2017

Molecular epigenetic approach activates silent gene cluster producing dimeric bis-spiro-azaphilones in Chaetomium globosum CBS148.51. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/JA.2017.4
P698PubMed publication ID28246383

P2093author name stringTao Jiang
Meng Yu
Gang Ding
Xue-Wei Wang
Zhong-Mei Zou
Yu-Cheng Gu
Meng-Hua Wang
Hong-Mei Jia
Shu-Bin Niu
Qiu-Bo Zhang
Jia-Huan Chen
P2860cites workFour new azaphilones from Chaetomium globosum var. flavo-viridae.Q104984568
Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrumQ33884671
Endophytes: a rich source of functional metabolitesQ34362946
Draft Genome Sequence of the Cellulolytic Fungus Chaetomium globosumQ35126476
Epigenetic genome mining of an endophytic fungus leads to the pleiotropic biosynthesis of natural productsQ35805909
Identification and characterization of the chaetoviridin and chaetomugilin gene cluster in Chaetomium globosum reveal dual functions of an iterative highly-reducing polyketide synthaseQ36386489
Epigenome manipulation as a pathway to new natural product scaffolds and their congenersQ37660083
Chemical and bioactive diversities of the genus Chaetomium secondary metabolitesQ37988918
Azaphilones: chemistry and biologyQ38098612
Strategies for mining fungal natural productsQ38154539
Fungal natural products in research and development.Q38239799
Discovery of microbial natural products by activation of silent biosynthetic gene clustersQ38539563
Chaetomugilins, new selectively cytotoxic metabolites, produced by a marine fish-derived Chaetomium speciesQ39890971
Targeted disruption of transcriptional regulators in Chaetomium globosum activates biosynthetic pathways and reveals transcriptional regulator-like behavior of aureonitol.Q43708512
11- and 4′-Epimers of Chaetomugilin A, Novel Cytostatic Metabolites from Marine Fish-Derived FungusChaetomium globosumQ78234693
Bis-spiro-azaphilones and azaphilones from the fungi Chaetomium cochliodes VTh01 and C. cochliodes CTh05Q78296149
Absolute stereostructures of cytotoxic metabolites, chaetomugilins A–C, produced by a Chaetomium species separated from a marine fishQ78297353
Azaphilones from the EndophyteChaetomium globosumQ78440929
Cytochrome P450 as dimerization catalyst in diketopiperazine alkaloid biosynthesisQ87544317
P433issue6
P921main subjectChaetomium globosumQ2947551
P304page(s)801-804
P577publication date2017-03-01
P1433published inThe Journal of AntibioticsQ7743552
P1476titleMolecular epigenetic approach activates silent gene cluster producing dimeric bis-spiro-azaphilones in Chaetomium globosum CBS148.51.
P478volume70

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