Paradoxical bleeding and thrombotic episodes of dysprothrombinaemia due to a homozygous Arg382His mutation.

scientific article published on 15 December 2016

Paradoxical bleeding and thrombotic episodes of dysprothrombinaemia due to a homozygous Arg382His mutation. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1160/TH16-10-0750
P932PMC publication ID5330935
P698PubMed publication ID27975099

P2093author name stringXuefeng Wang
Alireza R Rezaie
Likui Yang
Wenman Wu
Xiaoqing Zhao
Qiulan Ding
P2860cites workProtein C Thr315Ala variant results in gain of function but manifests as type II deficiency in diagnostic assaysQ24317483
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Hereditary prothrombin deficiency presenting as intracranial haematoma in infancyQ33856058
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Vascular Dermatan Sulfate and Heparin Cofactor IIQ37784316
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Molecular and functional characterization of a natural homozygous Arg67His mutation in the prothrombin gene of a patient with a severe procoagulant defect contrasting with a mild hemorrhagic phenotypeQ40714431
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New Prothrombin Mutation (Arg596Trp, Prothrombin Padua 2) Associated With Venous ThromboembolismQ45884368
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Prothrombin Himi: a compound heterozygote for two dysfunctional prothrombin molecules (Met-337-->Thr and Arg-388-->His)Q67919366
Thrombin-induced release of active basic fibroblast growth factor-heparan sulfate complexes from subendothelial extracellular matrixQ70751733
Genetic analysis and functional characterization of prothrombins Corpus Christi (Arg382-Cys), Dhahran (Arg271-His), and hypoprothrombinemiaQ71611763
Protein C Inhibitor Is a Potent Inhibitor of the Thrombin-Thrombomodulin ComplexQ71823602
Molecular events that control the protein C anticoagulant pathwayQ72595211
Regulation of fibrinolysis in plasma by TAFI and protein C is dependent on the concentration of thrombomodulinQ73503901
Role of proexosite I in factor Va-dependent substrate interactions of prothrombin activationQ73626480
Elements of the primary structure of thrombomodulin required for efficient thrombin-activable fibrinolysis inhibitor activationQ73762875
Plasma TAFI levels influence the clot lysis time in healthy individuals in the presence of an intact intrinsic pathway of coagulationQ77647784
Congenital deficiencies and abnormalities of prothrombinQ77719013
Thrombosis from a prothrombin mutation conveying antithrombin resistanceQ84420305
P433issue3
P921main subjecthomozygosityQ114049690
P304page(s)479-490
P577publication date2016-12-15
P1433published inThrombosis and HaemostasisQ15724413
P1476titleParadoxical bleeding and thrombotic episodes of dysprothrombinaemia due to a homozygous Arg382His mutation.
P478volume117

Reverse relations

cites work (P2860)
Q53132506Congenital prothrombin defects: they are not only associated with bleeding but also with thrombosis: a new classification is needed.
Q88460248Prothrombin: Another Clotting Factor After FV That Is Involved Both in Bleeding and Thrombosis

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