Viral gene transfer of dominant-negative Kv4 construct suppresses an O2-sensitive K+ current in chemoreceptor cells.

scientific article published in August 2000

Viral gene transfer of dominant-negative Kv4 construct suppresses an O2-sensitive K+ current in chemoreceptor cells. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1523/JNEUROSCI.20-15-05689.2000
P932PMC publication ID6772540
P698PubMed publication ID10908607

P50authorM T Pérez-GarcíaQ67670266
P2093author name stringC Gonzalez
E Marbán
D C Johns
U C Hoppe
A M Riesco
J R López-López
P2860cites workImproved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patchesQ22337395
Kv2.1/Kv9.3, a novel ATP-dependent delayed-rectifier K+ channel in oxygen-sensitive pulmonary artery myocytesQ24532822
Functional and molecular aspects of voltage-gated K+ channel beta subunitsQ28140255
Presynaptic A-current based on heteromultimeric K+ channels detected in vivoQ28573464
Contributions of Kv3 channels to neuronal excitabilityQ33868667
Carotid body chemoreceptors: from natural stimuli to sensory dischargesQ34324365
Chemotransduction in the carotid body: K+ current modulated by PO2 in type I chemoreceptor cellsQ34406527
Oxygen and acid chemoreception in the carotid body chemoreceptorsQ35318386
Four kinetically distinct depolarization-activated K+ currents in adult mouse ventricular myocytesQ36420431
Gating of O2-sensitive K+ channels of arterial chemoreceptor cells and kinetic modifications induced by low PO2Q36434911
Single K+ channels in membrane patches of arterial chemoreceptor cells are modulated by O2 tensionQ37469305
Ecdysone-inducible gene expression in mammalian cells and transgenic mice.Q37651825
Construction of adenovirus vectors through Cre-lox recombinationQ39878424
Oxygen sensitivity of cloned voltage-gated K(+) channels expressed in the pulmonary vasculature.Q40928912
Potential identification of the O2-sensitive K+ current in a human neuroepithelial body-derived cell lineQ40981209
Modulation of recombinant human cardiac L-type Ca2+ channel alpha1C subunits by redox agents and hypoxiaQ40981937
Suppression of KATP currents by gene transfer of a dominant negative Kir6.2 constructQ40997561
Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunitQ41009542
Myocardial potassium channels: electrophysiological and molecular diversityQ41117713
Shal-type channels contribute to the Ca2+-independent transient outward K+ current in rat ventricleQ41119466
Regions responsible for the assembly of inwardly rectifying potassium channelsQ41149815
Oxygen-sensitive ion channelsQ41679461
Potassium channel types in arterial chemoreceptor cells and their selective modulation by oxygenQ41781276
Kvbeta1.2 subunit coexpression in HEK293 cells confers O2 sensitivity to kv4.2 but not to Shaker channelsQ41918102
Subcellular segregation of two A-type K+ channel proteins in rat central neuronsQ42458250
Potassium currents recorded in type I carotid body cells from the neonatal rat and their modulation by chemoexcitatory agentsQ44037818
Suppression of neuronal and cardiac transient outward currents by viral gene transfer of dominant-negative Kv4.2 constructsQ44798839
Suppression of glomus cell K+ conductance by 4-aminopyridine is not related to [Ca2+]i, dopamine release and chemosensory discharge from carotid bodyQ48456342
Differential expression of Kv4 K+ channel subunits mediating subthreshold transient K+ (A-type) currents in rat brainQ48489960
Two types of voltage-gated K channels in carotid body cells of adult catsQ48831462
Quantitative single-cell-reverse transcription-PCR demonstrates that A-current magnitude varies as a linear function of shal gene expression in identified stomatogastric neurons.Q48952740
Assembly of mammalian voltage-gated potassium channels: evidence for an important role of the first transmembrane segmentQ49111609
Properties of ionic currents from isolated adult rat carotid body chemoreceptor cells: effect of hypoxia.Q52196034
Characterization of cultured chemoreceptor cells dissociated from adult rabbit carotid bodyQ67979114
Potassium channel mRNA expression in prevertebral and paravertebral sympathetic neuronsQ71273724
Properties of a transient K+ current in chemoreceptor cells of rabbit carotid bodyQ72969560
Inducible genetic suppression of neuronal excitabilityQ74452909
Molecular basis and function of voltage-gated K+ channels in pulmonary arterial smooth muscle cellsQ74518435
Manipulation of cellular excitability by cell fusion: effects of rapid introduction of transient outward K+ current on the guinea pig action potentialQ77381423
Molecular correlates of the calcium-independent, depolarization-activated K+ currents in rat atrial myocytesQ77760405
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectchemoreceptor cellQ1069641
P304page(s)5689-5695
P577publication date2000-08-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleViral gene transfer of dominant-negative Kv4 construct suppresses an O2-sensitive K+ current in chemoreceptor cells
P478volume20

Reverse relations

cites work (P2860)
Q36593644A role for DPPX modulating external TEA sensitivity of Kv4 channels
Q48263621Activation of voltage-dependent K+ channels strongly limits hypoxia-induced elevation of [Ca2+ ]i in rat carotid body glomus cells
Q44201760Antioxidants prevent depression of the acute hypoxic ventilatory response by subanaesthetic halothane in men.
Q34575382Blockade of Kv1.3 potassium channels inhibits differentiation and granzyme B secretion of human CD8+ T effector memory lymphocytes
Q47797805Down regulation of Kv3.4 channels by chronic hypoxia increases acute oxygen sensitivity in rabbit carotid body.
Q45937877EPAC signalling pathways are involved in low PO2 chemoreception in carotid body chemoreceptor cells.
Q27022670K(+) channels in O(2) sensing and postnatal development of carotid body glomus cell response to hypoxia
Q43890858Low glucose-sensing cells in the carotid body.
Q28574306Modulation of chronic hypoxia-induced chemoreceptor hypersensitivity by NADPH oxidase subunits in rat carotid body
Q42096889Molecular and pharmacological characteristics of transient voltage-dependent K+ currents in cultured human pulmonary arterial smooth muscle cells
Q44067072Molecular identification of Kvalpha subunits that contribute to the oxygen-sensitive K+ current of chemoreceptor cells of the rabbit carotid body.
Q47822483Molecular strategies for studying oxygen-sensitive K+ channels.
Q36246924Oxygen sensing in the body
Q29346980Regulation of Kv4.2 A-Type Potassium Channels in HEK-293 Cells by Hypoxia
Q44355549Rotenone selectively occludes sensitivity to hypoxia in rat carotid body glomus cells
Q34139832Significance of ROS in oxygen sensing in cell systems with sensitivity to physiological hypoxia
Q44476740The pore region of the Kv1.2alpha subunit is an important component of recombinant Kv1.2 channel oxygen sensitivity
Q43806084Tissue oxygen sensor function of NADPH oxidase isoforms, an unusual cytochrome aa3 and reactive oxygen species

Search more.