| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/978-3-319-41334-1_12 |
| P698 | PubMed publication ID | 27671821 |
| P2093 | author name string | Kamal D Moudgil | |
| Shivaprasad H Venkatesha | |||
| P2860 | cites work | Celastrol inhibits vasculogenesis by suppressing the VEGF-induced functional activity of bone marrow-derived endothelial progenitor cells | Q84344380 |
| Celastrol inhibits interleukin-17A-stimulated rheumatoid fibroblast-like synoviocyte migration and invasion through suppression of NF-κB-mediated matrix metalloproteinase-9 expression | Q84941273 | ||
| Celastrol induces the apoptosis of breast cancer cells and inhibits their invasion via downregulation of MMP-9 | Q85770410 | ||
| RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK) | Q22004168 | ||
| Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin. | Q24540159 | ||
| Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals | Q24631327 | ||
| Anti-angiogenic alternatives to VEGF blockade | Q26775947 | ||
| Celastrol, an NF-κB inhibitor, improves insulin resistance and attenuates renal injury in db/db mice | Q27323293 | ||
| Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains | Q28114920 | ||
| Celastrol prevents atherosclerosis via inhibiting LOX-1 and oxidative stress | Q28533974 | ||
| STATs and gene regulation | Q29547796 | ||
| The heat-shock proteins | Q29617227 | ||
| NF-kappaB: a key role in inflammatory diseases | Q29617726 | ||
| Celastrol inhibits aminoglycoside-induced ototoxicity via heat shock protein 32. | Q30473659 | ||
| Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease | Q33499111 | ||
| Development of HIF-1 inhibitors for cancer therapy | Q33703381 | ||
| Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaB | Q33775541 | ||
| Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway | Q33787400 | ||
| Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors | Q33799792 | ||
| HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way | Q33864144 | ||
| Celastrol targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent cytotoxicity in tumor cells | Q33899137 | ||
| Report of 12 cases of ankylosing spondylitis patients treated with Tripterygium wilfordii | Q34014598 | ||
| Angiogenesis in rheumatoid arthritis. | Q34051829 | ||
| The role of angiogenesis in rheumatoid arthritis: recent developments | Q34071300 | ||
| Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease | Q34087457 | ||
| Celastrol acts as a potent antimetastatic agent targeting beta1 integrin and inhibiting cell-extracellular matrix adhesion, in part via the p38 mitogen-activated protein kinase pathway | Q34115610 | ||
| Comparison of Tripterygium wilfordii Hook F versus sulfasalazine in the treatment of rheumatoid arthritis: a randomized trial | Q34124686 | ||
| Celastrus-derived celastrol suppresses autoimmune arthritis by modulating antigen-induced cellular and humoral effector responses | Q34170674 | ||
| Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network. | Q34280571 | ||
| Celastrol stimulates hypoxia-inducible factor-1 activity in tumor cells by initiating the ROS/Akt/p70S6K signaling pathway and enhancing hypoxia-inducible factor-1α protein synthesis | Q34482963 | ||
| Celastrol regulates multiple nuclear transcription factors belonging to HSP90's clients in a dose- and cell type-dependent way. | Q34505759 | ||
| Tumor necrosis factor-α sensitizes breast cancer cells to natural products with proteasome-inhibitory activity leading to apoptosis | Q34566295 | ||
| Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system. | Q34788381 | ||
| Heat shock proteins in neurodegenerative diseases: pathogenic roles and therapeutic implications | Q43215480 | ||
| Pharmacologic inhibitors of IkappaB kinase suppress growth and migration of mammary carcinosarcoma cells in vitro and prevent osteolytic bone metastasis in vivo | Q43293831 | ||
| Celastrol, a triterpene extracted from Tripterygium wilfordii Hook F, inhibits platelet activation | Q43297037 | ||
| Reverse Fox test for detecting visuospatial dysfunction corresponding to parietal hypoperfusion in mild Alzheimer's disease | Q43758083 | ||
| Celastrol suppresses obesity process via increasing antioxidant capacity and improving lipid metabolism | Q44133126 | ||
| The triterpene celastrol as a very potent inhibitor of lipid peroxidation in mitochondria | Q44944429 | ||
| Anti-invasive effects of celastrol in hypoxia-induced fibroblast-like synoviocyte through suppressing of HIF-1α/CXCR4 signaling pathway. | Q45933330 | ||
| Beneficial effect of tripterine on systemic lupus erythematosus induced by active chromatin in BALB/c mice | Q46445649 | ||
| Therapeutic effect of tripterine on adjuvant arthritis in rats | Q46520706 | ||
| Celastrol protects against MPTP- and 3-nitropropionic acid-induced neurotoxicity. | Q46644015 | ||
| Novel skeleton terpenes from Celastrus hypoleucus with anti-tumor activities | Q46925217 | ||
| Traditional Chinese medicine: potential for clinical treatment of rheumatoid arthritis | Q47644841 | ||
| Celastrol suppresses allergen-induced airway inflammation in a mouse allergic asthma model | Q48030488 | ||
| Celastrol Ameliorates EAE Induction by Suppressing Pathogenic T Cell Responses in the Peripheral and Central Nervous Systems | Q48095829 | ||
| Modulatory effect of celastrol on Th1/Th2 cytokines profile, TLR2 and CD3+ T-lymphocyte expression in a relapsing-remitting model of multiple sclerosis in rats | Q48545134 | ||
| Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo | Q50251514 | ||
| Celastrol isolated from Tripterygium regelii induces apoptosis through both caspase-dependent and -independent pathways in human breast cancer cells. | Q53285162 | ||
| Celastrol ameliorates experimental colitis in IL-10 deficient mice via the up-regulation of autophagy. | Q53548636 | ||
| The effect of celastrol, a triterpene with antitumorigenic activity, on conformational and functional aspects of the human 90kDa heat shock protein Hsp90α, a chaperone implicated in the stabilization of the tumor phenotype. | Q53900592 | ||
| Structural basis of potent antiperoxidation activity of the triterpene celastrol in mitochondria: effect of negative membrane surface charge on lipid peroxidation. | Q54195784 | ||
| Effects of tripterine on mRNA expression of TGF-beta1 and collagen IV expression in BW F1 mice. | Q54586158 | ||
| Comparison ofTripterygium wilfordiiHook F with methotrexate in the treatment of active rheumatoid arthritis (TRIFRA): a randomised, controlled clinical trial | Q57603196 | ||
| Inhibition of NF-κB activation through targeting IκB kinase by celastrol, a quinone methide triterpenoid | Q58802946 | ||
| Free radicals and metal ions in health and disease | Q69002055 | ||
| Benefit of an extract of Tripterygium Wilfordii Hook F in patients with rheumatoid arthritis: a double-blind, placebo-controlled study | Q74479808 | ||
| Antiinflammatory constituents of Celastrus orbiculatus inhibit the NF-kappaB activation and NO production | Q77541188 | ||
| Celastrol blocks neuronal cell death and extends life in transgenic mouse model of amyotrophic lateral sclerosis | Q80112328 | ||
| Antifungal properties of pristimerin and celastrol isolated from Celastrus hypoleucus | Q81128754 | ||
| Celastrol inhibits lipopolysaccharide-stimulated rheumatoid fibroblast-like synoviocyte invasion through suppression of TLR4/NF-κB-mediated matrix metalloproteinase-9 expression | Q34828241 | ||
| Suppression of inflammatory responses by celastrol, a quinone methide triterpenoid isolated from Celastrus regelii | Q34988475 | ||
| Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets. | Q35023644 | ||
| Celastrol inhibits Tat-mediated human immunodeficiency virus (HIV) transcription and replication. | Q35119118 | ||
| Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor. | Q35125413 | ||
| Celastrol blocks interleukin-6 gene expression via downregulation of NF-κB in prostate carcinoma cells | Q35130330 | ||
| Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer | Q35155622 | ||
| Celastrol, a Chinese herbal compound, controls autoimmune inflammation by altering the balance of pathogenic and regulatory T cells in the target organ | Q35539225 | ||
| Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells. | Q35564293 | ||
| Effect of celastrol on growth inhibition of prostate cancer cells through the regulation of hERG channel in vitro | Q35600054 | ||
| Regulation of JAK-STAT signalling in the immune system | Q35605437 | ||
| Oxidative stress, redox regulation and diseases of cellular differentiation | Q35611511 | ||
| Celastrol ameliorates cytokine toxicity and pro-inflammatory immune responses by suppressing NF-κB activation in RINm5F beta cells | Q35676351 | ||
| Natural compounds with proteasome inhibitory activity for cancer prevention and treatment | Q35828472 | ||
| Modulation of neurodegeneration by molecular chaperones | Q35990274 | ||
| Celastrus and its bioactive celastrol protect against bone damage in autoimmune arthritis by modulating osteoimmune cross-talk | Q36052535 | ||
| MAPK signalling pathways as molecular targets for anti-inflammatory therapy--from molecular mechanisms to therapeutic benefits | Q36273853 | ||
| Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells: an in vitro and in vivo study | Q36347072 | ||
| Defining therapeutic targets by using adenovirus: blocking NF-kappaB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators | Q36364193 | ||
| Celastrus aculeatus Merr. suppresses the induction and progression of autoimmune arthritis by modulating immune response to heat-shock protein 65. | Q36392363 | ||
| Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule. | Q36489064 | ||
| Antiangiogenic therapy for cancer: an update | Q36563542 | ||
| Treatment of obesity with celastrol | Q36623157 | ||
| Effective treatment of rat adjuvant-induced arthritis by celastrol | Q36638712 | ||
| Celastrol inhibits Plasmodium falciparum enoyl-acyl carrier protein reductase | Q36729008 | ||
| Signalling, inflammation and arthritis: NF-kappaB and its relevance to arthritis and inflammation. | Q37072150 | ||
| Heat-shock proteins can promote as well as regulate autoimmunity | Q37157653 | ||
| Tripterine prevents endothelial barrier dysfunction by inhibiting endogenous peroxynitrite formation | Q37332651 | ||
| Celastrol potentiates radiotherapy by impairment of DNA damage processing in human prostate cancer | Q37349650 | ||
| Celastrol increases glucocerebrosidase activity in Gaucher disease by modulating molecular chaperones. | Q37475206 | ||
| Triterpenoids as new promising anticancer drugs. | Q37595309 | ||
| Heat shock proteins as suppressors of accumulation of toxic prefibrillar intermediates and misfolded proteins in neurodegenerative diseases | Q37695315 | ||
| Celastrol: Molecular targets of Thunder God Vine | Q37708343 | ||
| Targeting apoptosis pathways in cancer by Chinese medicine | Q37777759 | ||
| Molecular targets of celastrol derived from Thunder of God Vine: potential role in the treatment of inflammatory disorders and cancer. | Q37822109 | ||
| The main anticancer bullets of the Chinese medicinal herb, thunder god vine. | Q37893952 | ||
| Tripterygium wilfordii bioactive compounds as anticancer and anti-inflammatory agents. | Q37915623 | ||
| The complexity of NF-κB signaling in inflammation and cancer | Q38126565 | ||
| Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway | Q38170894 | ||
| Cellular mechanisms and physiological consequences of redox-dependent signalling | Q38214052 | ||
| The PI3K/AKT/mTOR pathway as a therapeutic target in ovarian cancer. | Q38353745 | ||
| Effects of Plants and Isolates of Celastraceae Family on Cancer Pathways. | Q38382151 | ||
| Control of autoimmune inflammation by celastrol, a natural triterpenoid | Q38894091 | ||
| Celastrol attenuates bone erosion in collagen-Induced arthritis mice and inhibits osteoclast differentiation and function in RANKL-induced RAW264.7. | Q38926488 | ||
| Celastrol ameliorates HIV-1 Tat-induced inflammatory responses via NF-kappaB and AP-1 inhibition and heme oxygenase-1 induction in astrocytes | Q38971470 | ||
| Celastrol inhibits the HIF-1α pathway by inhibition of mTOR/p70S6K/eIF4E and ERK1/2 phosphorylation in human hepatoma cells | Q38991750 | ||
| Celastrol induces apoptosis of gastric cancer cells by miR-21 inhibiting PI3K/Akt-NF-κB signaling pathway | Q39033757 | ||
| Celastrol from 'Thunder God Vine' protects SH-SY5Y cells through the preservation of mitochondrial function and inhibition of p38 MAPK in a rotenone model of Parkinson's disease | Q39064812 | ||
| Celastrol inhibits lipopolysaccharide-induced angiogenesis by suppressing TLR4-triggered nuclear factor-kappa B activation | Q39070877 | ||
| Celastrol induced DNA damage, cell cycle arrest, and apoptosis in human rheumatoid fibroblast-like synovial cells | Q39147029 | ||
| Localization of heat shock proteins in cerebral cortical cultures following induction by celastrol | Q39393819 | ||
| Celastrol-induced apoptosis in human HaCaT keratinocytes involves the inhibition of NF-κB activity | Q39467325 | ||
| Paraptosis accompanied by autophagy and apoptosis was induced by celastrol, a natural compound with influence on proteasome, ER stress and Hsp90. | Q39484780 | ||
| Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways | Q39501449 | ||
| Celastrol regulates innate immunity response via NF-κB and Hsp70 in human retinal pigment epithelial cells | Q39522626 | ||
| Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease | Q39686268 | ||
| Celastrol binds to ERK and inhibits FcepsilonRI signaling to exert an anti-allergic effect | Q39862659 | ||
| Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression | Q40002174 | ||
| Celastrol inhibits production of nitric oxide and proinflammatory cytokines through MAPK signal transduction and NF-kappaB in LPS-stimulated BV-2 microglial cells | Q40030520 | ||
| Induction of heat shock proteins in differentiated human and rodent neurons by celastrol | Q40072158 | ||
| Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation | Q40207449 | ||
| Tripterine inhibits the expression of adhesion molecules in activated endothelial cells. | Q40268720 | ||
| Celastrols as inducers of the heat shock response and cytoprotection. | Q40499125 | ||
| Anticancer effect of celastrol on human triple negative breast cancer: possible involvement of oxidative stress, mitochondrial dysfunction, apoptosis and PI3K/Akt pathways | Q41146978 | ||
| Heat shock protein 90 inhibitors suppress aryl hydrocarbon receptor-mediated activation of CYP1A1 and CYP1B1 transcription and DNA adduct formation | Q42082052 | ||
| Simultaneous NF-κB inhibition and E-cadherin upregulation mediate mutually synergistic anticancer activity of celastrol and SAHA in vitro and in vivo. | Q42647696 | ||
| Celastrol enhances Nrf2 mediated antioxidant enzymes and exhibits anti-fibrotic effect through regulation of collagen production against bleomycin-induced pulmonary fibrosis | Q42699746 | ||
| The Safety and Effectiveness of a Chloroform/Methanol Extract of Tripterygium wilfordii Hook F (T2) Plus Methotrexate in Treating Rheumatoid Arthritis | Q42804898 | ||
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 267-289 | |
| P577 | publication date | 2016-01-01 | |
| P1433 | published in | Advances in Experimental Medicine and Biology | Q4686385 |
| P1476 | title | Celastrol and Its Role in Controlling Chronic Diseases. | |
| P478 | volume | 928 |
| Q41549202 | A unique tolerizing dendritic cell phenotype induced by the synthetic triterpenoid CDDO-DFPA (RTA-408) is protective against EAE. |
| Q38940839 | Celastrol Attenuates Multiple Sclerosis and Optic Neuritis in an Experimental Autoimmune Encephalomyelitis Model |
| Q55415494 | Celastrol alleviates renal fibrosis by upregulating cannabinoid receptor 2 expression. |
| Q92027098 | Celastrol suppresses experimental autoimmune encephalomyelitis via MAPK/SGK1-regulated mediators of autoimmune pathology |
| Q53681639 | Chemopreventive activity of celastrol in drug-resistant human colon carcinoma cell cultures. |
| Q49364060 | Genetic Transformation System for Woody Plant Tripterygium wilfordii and Its Application to Product Natural Celastrol. |
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| Q61813424 | Tripterine up-regulates miR-223 to alleviate lipopolysaccharide-induced damage in murine chondrogenic ATDC5 cells |
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