scholarly article | Q13442814 |
P356 | DOI | 10.3109/00498259609050260 |
P698 | PubMed publication ID | 8948091 |
P2093 | author name string | F J Gonzalez | |
T Satoh | |||
S Miyazawa | |||
S Ono | |||
T Aoyama | |||
T Hatanaka | |||
M Tsutsui | |||
P2860 | cites work | Evidence that CYP2C19 is the major (S)-mephenytoin 4'-hydroxylase in humans | Q24323988 |
cDNA and amino acid sequences of two members of the human P450IIC gene subfamily | Q24631075 | ||
CYP3A gene expression in human gut epithelium | Q28236591 | ||
Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver | Q28243581 | ||
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes | Q28281124 | ||
Biochemistry and molecular biology of the human CYP2C subfamily | Q28299258 | ||
Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P450 metabolically activate aflatoxin B1 | Q33645193 | ||
Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms | Q34346567 | ||
Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations | Q34695612 | ||
cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver | Q35570503 | ||
Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man | Q35580014 | ||
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes | Q35608569 | ||
Genetic polymorphism of S-mephenytoin hydroxylation | Q38692055 | ||
The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature | Q40484461 | ||
Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes | Q41187611 | ||
Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions | Q44735365 | ||
Incidence of S-mephenytoin hydroxylation deficiency in a Korean population and the interphenotypic differences in diazepam pharmacokinetics. | Q51686117 | ||
Diazepam metabolism by rat and human liver in vitro: inhibition by mephenytoin | Q51692236 | ||
Importance of genetic factors in the regulation of diazepam metabolism: relationship to S-mephenytoin, but not debrisoquin, hydroxylation phenotype. | Q51755470 | ||
Determination of diazepam and oxazepam using high-performance liquid chromatography and fourth-derivative spectrophotometric techniques. | Q51767867 | ||
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | diazepam | Q210402 |
P304 | page(s) | 1155-1166 | |
P577 | publication date | 1996-11-01 | |
P1433 | published in | Xenobiotica | Q1360678 |
P1476 | title | Human liver microsomal diazepam metabolism using cDNA-expressed cytochrome P450s: role of CYP2B6, 2C19 and the 3A subfamily. | |
P478 | volume | 26 |
Q47963518 | A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways. |
Q44202384 | A study of the in vitro clinical interaction between lidocaine and premedications using rat liver microsomes |
Q34824471 | CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme |
Q34405394 | Classics in chemical neuroscience: diazepam (valium). |
Q35129382 | Clinically Important Drug Interactions with Zopiclone, Zolpidem and Zaleplon |
Q36375369 | Genetic polymorphisms and phenotypic analysis of drug-metabolizing enzyme CYP2C19 in a Li Chinese population |
Q37176949 | Genotype-phenotype analysis of CYP2C19 in healthy saudi individuals and its potential clinical implication in drug therapy |
Q36624080 | Genotype‑phenotype analysis of CYP2C19 in the Tibetan population and its potential clinical implications in drug therapy |
Q34430456 | Human drug metabolism and the cytochromes P450: application and relevance of in vitro models |
Q51467454 | Human, rat and crocodile liver microsomal monooxygenase activities measured using diazepam and nifedipine: effects of CYP3A inhibitors and relationship to immunochemically detected CYP3A apoprotein. |
Q93921946 | Identification of cytochrome P450 enzymes involved in the metabolism of zotepine, an antipsychotic drug, in human liver microsomes |
Q45065966 | Inhibitory effects of memantine on human cytochrome P450 activities: prediction of in vivo drug interactions |
Q28078857 | Insights into CYP2B6-mediated drug-drug interactions |
Q35185727 | Pharmacokinetic interactions with rifampicin : clinical relevance |
Q46906656 | Prediction of cytochrome p450-mediated hepatic drug clearance in neonates, infants and children : how accurate are available scaling methods? |
Q47900761 | Relative quantities of catalytically active CYP 2C9 and 2C19 in human liver microsomes: application of the relative activity factor approach |
Q40949921 | Sigmoidal kinetic model for two co-operative substrate-binding sites in a cytochrome P450 3A4 active site: an example of the metabolism of diazepam and its derivatives |
Q34657381 | Sucralose, a synthetic organochlorine sweetener: overview of biological issues |
Q44103372 | The N-demethylation of the doxepin isomers is mainly catalyzed by the polymorphic CYP2C19. |
Q80381085 | Tramadol-benzodiazepines and buprenorphine-benzodiazepines: two potentially fatal cocktails? |
Q28142314 | Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism |
Search more.