scholarly article | Q13442814 |
P2093 | author name string | Baillie TA | |
Dai R | |||
Rushmore TH | |||
Shou M | |||
Mei Q | |||
Ettore MW Jr | |||
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Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms | Q34346567 | ||
Human P450PCN1: sequence, chromosome localization, and direct evidence through cDNA expression that P450PCN1 is nifedipine oxidase | Q36444100 | ||
Analysis of human cytochrome P450 3A4 cooperativity: construction and characterization of a site-directed mutant that displays hyperbolic steroid hydroxylation kinetics | Q36481303 | ||
Factors influencing the metabolism of diazepam | Q38140211 | ||
The molecular biology of cytochrome P450s. | Q39572384 | ||
Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins | Q40700838 | ||
Catalytic properties of the human cytochrome P450 2E1 produced by cDNA expression in mammalian cells | Q41594075 | ||
CO binding kinetics of human cytochrome P450 3A4. Specific interaction of substrates with kinetically distinguishable conformers. | Q42066742 | ||
Cytochrome P450IIIA enzymes in rat liver microsomes: involvement in C3-hydroxylation of diazepam and nordazepam but not N-dealkylation of diazepam and temazepam. | Q44331755 | ||
The active sites of cytochromes P450 IA1, IIB1, IIB2, and IIE1. Topological analysis by in situ rearrangement of phenyl-iron complexes | Q44385054 | ||
Human NADPH-P450 oxidoreductase: complementary DNA cloning, sequence and vaccinia virus-mediated expression and localization of the CYPOR gene to chromosome 7. | Q45846758 | ||
Modulation of rabbit and human hepatic cytochrome P-450-catalyzed steroid hydroxylations by alpha-naphthoflavone | Q46347169 | ||
Activation of CYP3A4: evidence for the simultaneous binding of two substrates in a cytochrome P450 active site | Q50120037 | ||
Role of cDNA-expressed human cytochromes P450 in the metabolism of diazepam. | Q51521960 | ||
Diazepam metabolism by cDNA-expressed human 2C P450s: identification of P4502C18 and P4502C19 as low K(M) diazepam N-demethylases. | Q51549688 | ||
Cooperativity in oxidations catalyzed by cytochrome P450 3A4. | Q51550149 | ||
Human liver microsomal diazepam metabolism using cDNA-expressed cytochrome P450s: role of CYP2B6, 2C19 and the 3A subfamily. | Q51558252 | ||
Inhibitory and non-inhibitory monoclonal antibodies to human cytochrome P450 3A3/4. | Q51588494 | ||
Kinetics of diazepam metabolism in rat hepatic microsomes and hepatocytes and their use in predicting in vivo hepatic clearance. | Q51594979 | ||
Characterization of specific cytochrome P450 enzymes responsible for the metabolism of diazepam in hepatic microsomes of adult male rats. | Q51673373 | ||
Metabolism of diazepam and related benzodiazepines by human liver microsomes. | Q51699901 | ||
[Interaction of coumarin-hydroxylating cytochrome P-450coh from liver microsomes of mice induced by pyrazole with cytochrome b5] | Q68357443 | ||
The interaction of cytochrome b5 with four cytochrome P-450 enzymes from the untreated rat | Q69868236 | ||
Purification and characterization of six cytochrome P-450 isozymes from human liver microsomes | Q70458093 | ||
N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors | Q71513231 | ||
Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation | Q72014034 | ||
Cytochrome P450 conformation and substrate interactions as probed by CO binding kinetics | Q73017807 | ||
Evaluation of atypical cytochrome P450 kinetics with two-substrate models: evidence that multiple substrates can simultaneously bind to cytochrome P450 active sites | Q74378005 | ||
KINETICS OF REGULATORY ENZYMES. KINETIC ORDER OF THE YEAST DIPHOSPHOPYRIDINE NUCLEOTIDE ISOCITRATE DEHYDROGENASE REACTION AND A MODEL FOR THE REACTION | Q78405723 | ||
P407 | language of work or name | English | Q1860 |
P921 | main subject | diazepam | Q210402 |
P1104 | number of pages | 9 | |
P304 | page(s) | 845-853 | |
P577 | publication date | 1999-06-01 | |
P1433 | published in | Biochemical Journal | Q864221 |
P1476 | title | Sigmoidal kinetic model for two co-operative substrate-binding sites in a cytochrome P450 3A4 active site: an example of the metabolism of diazepam and its derivatives | |
P478 | volume | 340 ( Pt 3) |
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