scholarly article | Q13442814 |
P356 | DOI | 10.1210/JC.83.2.604 |
P698 | PubMed publication ID | 9467581 |
P50 | author | Steven E. Kahn | Q41640212 |
P2093 | author name string | Schwartz RS | |
Porte D Jr | |||
Røder ME | |||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | patient | Q181600 |
P304 | page(s) | 604-608 | |
P577 | publication date | 1998-02-01 | |
P1433 | published in | The Journal of Clinical Endocrinology and Metabolism | Q3186902 |
P1476 | title | Disproportionately elevated proinsulin levels reflect the degree of impaired B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus. | |
P478 | volume | 83 |
Q92646840 | A Single 48 mg Sucralose Sip Unbalances Monocyte Subpopulations and Stimulates Insulin Secretion in Healthy Young Adults |
Q51368107 | A common variant upstream of the PAX6 gene influences islet function in man. |
Q92346474 | Adverse effects of noise stress on glucose homeostasis and insulin resistance in Sprague-Dawley rats |
Q51442468 | Association of variants of the TCF7L2 gene with increases in the risk of type 2 diabetes and the proinsulin:insulin ratio in the Spanish population. |
Q40391316 | Beta cell dysfunction in patients with acute myocardial infarction but without previously known type 2 diabetes: a report from the GAMI study |
Q34082827 | Beta-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass |
Q36198965 | Beta-cell preservation: a potential role for thiazolidinediones to improve clinical care in Type 2 diabetes |
Q35325334 | Both fasting and glucose-stimulated proinsulin levels predict hyperglycemia and incident type 2 diabetes: a population-based study of 9,396 Finnish men |
Q79251366 | Clinical and Laboratory Evaluation of Specific Chemiluminescence Assays for Intact and Total Proinsulin |
Q92026863 | Clinical potential of treatment with semaglutide in type 2 diabetes patients |
Q89525746 | Different β-cell secretory phenotype in non-obese compared to obese early type 2 diabetes |
Q51561862 | Dynamic changes in plasma proinsulin/insulin ratio during insulin secretion influence correlation between radioimmunoassay (RIA) and IMX measurements of insulin. |
Q37072675 | Effect of glucagon-like peptide-1 on beta- and alpha-cell function in isolated islet and whole pancreas transplant recipients |
Q41097981 | Efficacy and Safety of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin on Atherosclerosis, β-Cell Function, and Glycemic Control in Japanese Patients with Type 2 Diabetes Mellitus Who are Treatment Naïve or Poorly Responsive to Antidiabetes Agents: |
Q51478110 | Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, compared with the sulfonylurea, glipizide, in patients with type 2 diabetes inadequately controlled on metformin alone: a randomized, double-blind, non-inferiority trial. |
Q36340420 | Elevated Intact Proinsulin Levels During an Oral Glucose Challenge Indicate Progressive ß-Cell Dysfunction and May Be Predictive for Development of Type 2 Diabetes |
Q37896746 | Elevated intact proinsulin levels are indicative of Beta-cell dysfunction, insulin resistance, and cardiovascular risk: impact of the antidiabetic agent pioglitazone |
Q38711086 | Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell |
Q37277966 | Endocrine secretory reserve and proinsulin processing in recipients of islet of langerhans versus whole pancreas transplants |
Q37257592 | Evidence for association between polycystic ovary syndrome (PCOS) and TCF7L2 and glucose intolerance in women with PCOS and TCF7L2. |
Q49608463 | Genetic aetiology of glycaemic traits: approaches and insights |
Q24635872 | Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes |
Q46469531 | Genome-wide linkage scans for prediabetes phenotypes in response to 20 weeks of endurance exercise training in non-diabetic whites and blacks: the HERITAGE Family Study. |
Q37380977 | Glucose-modulated tyrosine nitration in beta cells: targets and consequences |
Q60045035 | Haematological parameters and lipid profile abnormalities among patients with Type-2 diabetes mellitus in Ghana |
Q37021217 | Hyperglycemia, insulin resistance, impaired pancreatic β-cell function, and risk of pancreatic cancer. |
Q51512241 | Hyperproinsulinaemia and risk of Type 2 diabetes mellitus in women. |
Q47105030 | Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation |
Q26859885 | Insights into the genetic basis of type 2 diabetes |
Q36830607 | Insulin Sensitivity and β-Cell Function Improve after Gastric Bypass in Severely Obese Adolescents |
Q33730511 | Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells |
Q44374903 | Insulin sensitivity and beta-cell secretion in thalassaemia major with secondary haemochromatosis: assessment by oral glucose tolerance test |
Q53788406 | Intolerable secretion and diabetes in tolerant transgenic mice, revisited. |
Q35049845 | Ipragliflozin: A novel sodium-glucose cotransporter 2 inhibitor developed in Japan |
Q35064524 | Level of proinsulin in association with cardiovascular risk factors and sleep snoring |
Q37933408 | Liraglutide: clinical pharmacology and considerations for therapy |
Q37915629 | Localized amyloids important in diseases outside the brain--lessons from the islets of Langerhans and the thoracic aorta |
Q92186029 | Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes |
Q46372448 | Markers of Oxidative Stress and Antioxidant Defense in Romanian Patients with Type 2 Diabetes Mellitus and Obesity |
Q34657175 | Mechanism linking diabetes mellitus and obesity |
Q37921910 | New type 2 diabetes risk genes provide new insights in insulin secretion mechanisms |
Q51256824 | Non-alcoholic fatty liver disease and impaired proinsulin conversion as newly identified predictors of the long-term non-response to a lifestyle intervention for diabetes prevention: results from the TULIP study. |
Q34549794 | Noncerebral Amyloidoses: Aspects on Seeding, Cross-Seeding, and Transmission |
Q35557360 | Pancreatic beta-cell loss and preservation in type 2 diabetes |
Q53499112 | Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion. |
Q42209549 | Post-renal transplant diabetes mellitus in korean subjects: superimposition of transplant-related immunosuppressant factors on genetic and type 2 diabetic risk factors |
Q36209699 | Prediction of Impending Type 1 Diabetes through Automated Dual-Label Measurement of Proinsulin:C-Peptide Ratio. |
Q44362519 | Proinsulin and acute insulin response independently predict Type 2 diabetes mellitus in men--report from 27 years of follow-up study |
Q51374590 | Proinsulin and the proinsulin/insulin ratio in overweight and obese children and adolescents: relation to clinical parameters, insulin resistance, and impaired glucose regulation. |
Q81323909 | Proinsulin levels and the proinsulin:c-peptide ratio complement autoantibody measurement for predicting type 1 diabetes |
Q42949026 | Proinsulin levels in patients with pancreatic diabetes are associated with functional changes in insulin secretion rather than pancreatic β-cell area |
Q46114555 | Proinsulin-to-C-peptide ratio versus proinsulin-to-insulin ratio in the prediction of incident diabetes: the Insulin Resistance Atherosclerosis Study (IRAS). |
Q35132429 | Rapid deterioration of insulin secretion in obese adolescents preceding the onset of type 2 diabetes. |
Q36918737 | Relative levels of the proprotein and cleavage-activated form of circulating human anti-Müllerian hormone are sexually dimorphic and variable during the life cycle. |
Q34382453 | Significant association of insulin and proinsulin with clustering of cardiovascular risk factors |
Q27315224 | Sox17 regulates insulin secretion in the normal and pathologic mouse β cell |
Q51361908 | Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes. |
Q37782506 | Targeting β-Cell Function Early in the Course of Therapy for Type 2 Diabetes Mellitus |
Q46085427 | The A-chain of insulin is a hot-spot for CD4+ T cell epitopes in human type 1 diabetes. |
Q33853306 | The PTPN22 C1858T gene variant is associated with proinsulin in new-onset type 1 diabetes |
Q52583445 | The Receptor for Advanced Glycation Endproducts is a mediator of toxicity by IAPP and other proteotoxic aggregates: Establishing and Exploiting Common Ground for Novel Amyloidosis Therapies. |
Q46459513 | The abnormalities of carbohydrate metabolism in Turner syndrome: analysis of risk factors associated with impaired glucose tolerance |
Q51376983 | The effect of initial therapy with the fixed-dose combination of sitagliptin and metformin compared with metformin monotherapy in patients with type 2 diabetes mellitus. |
Q33603369 | The once-daily human glucagon-like peptide-1 analog, liraglutide, improves β-cell function in Japanese patients with type 2 diabetes |
Q36013553 | The pancreatic beta cell surface proteome |
Q35038525 | The proinsulin/insulin (PI/I) ratio is reduced by postprandial targeting therapy in type 2 diabetes mellitus: a small-scale clinical study |
Q37150550 | The role of peroxisome proliferator‐activated receptor γ in pancreatic β cell function and survival: therapeutic implications for the treatment of type 2 diabetes mellitus |
Q40354164 | The serum levels of proinsulin and their relationship with IGFBP-1 in obese children |
Q41690304 | Type 2 Diabetes Prevention: Implications of Hemoglobin A1c Genetics |
Q46909320 | Variations in the four and a half LIM domains 1 gene (FHL1) are associated with fasting insulin and insulin sensitivity responses to regular exercise. |
Search more.