Modulation of Immunologic Response by Preventive Everolimus Application in a Rat CPB Model.

scientific article published on 29 July 2016

Modulation of Immunologic Response by Preventive Everolimus Application in a Rat CPB Model. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10753-016-0412-5
P698PubMed publication ID27473158

P50authorPayam AkhyariQ51066626
P2093author name stringAntonio Pinto
Artur Lichtenberg
Udo Boeken
Alexander Jenke
Annika Jahn
Moritz Benjamin Immohr
Laura Döhrn
Markus Kornfeld
P2860cites workPhosphorylation and regulation of Akt/PKB by the rictor-mTOR complexQ24295120
Ischemia/reperfusion activates myocardial innate immune response: the key role of the toll-like receptorQ28082430
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Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networksQ28255399
Fluvastatin synergistically improves the antiproliferative effect of everolimus on rat smooth muscle cells by altering p27Kip1/cyclin E expressionQ28571168
Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasisQ28585415
Degree of hypothermia in aortic arch surgery - optimal temperature for cerebral and spinal protection: deep hypothermia remains the gold standard in the absence of randomized dataQ30663478
Combined enzymatic and antioxidative treatment reduces ischemia-reperfusion injury in rabbit skeletal muscleQ33233109
Clinical pharmacokinetics of everolimusQ33358752
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Role of blood cells in ischaemia-reperfusion induced endothelial barrier failure.Q33954952
Phase I pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumorsQ34010378
Wound healing complications and the use of mammalian target of rapamycin inhibitors in kidney transplantation: a critical review of the literatureQ34297088
Modern temperature management in aortic arch surgery: the dilemma of moderate hypothermiaQ34341860
S6K1 and mTOR regulate Rac1-driven platelet activation and aggregation.Q35220422
The systemic inflammatory response to cardiopulmonary bypassQ35561177
Everolimus induces rapid plasma glucose normalization in insulinoma patients by effects on tumor as well as normal tissuesQ35584938
Rapamycin inhibits release of tumor necrosis factor-alpha from human vascular smooth muscle cells.Q35780238
The interleukin (IL)-2 family cytokines: survival and proliferation signaling pathways in T lymphocytesQ35804133
The pleiotropic effects of mTor inhibitorsQ35981412
Effect of everolimus on the immunomodulation of the human neutrophil inflammatory response and activationQ36302824
Modulation of systemic inflammatory response after cardiac surgeryQ36320195
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heartQ37256152
Everolimus: efficacy and safety in cardiac transplantationQ37779322
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Corticosteroids for the inflammatory response to cardiopulmonary bypass: an updateQ38066285
Identification of inflammatory mediators and their modulation by strategies for the management of the systemic inflammatory response during cardiac surgeryQ38070454
The role of everolimus in liver transplantationQ38248591
Acute kidney injury in severe sepsis: pathophysiology, diagnosis, and treatment recommendationsQ38407334
Cross-regulation of cytokine signalling: pro-inflammatory cytokines restrict IL-6 signalling through receptor internalisation and degradationQ39732644
The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney. Inhibition by a soluble P-selectin ligandQ39785346
Perioperative Dynamics of TLR2, TLR4, and TREM-1 Expression in Monocyte Subpopulations in the Setting of On-Pump Coronary Artery Bypass SurgeryQ41836365
Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidaseQ42062495
A cardiopulmonary bypass with deep hypothermic circulatory arrest rat model for the investigation of the systemic inflammation response and induced organ damage.Q43004985
Effects of everolimus on cytokines, oxidative stress, and renal histology in ischemia-reperfusion injury of the kidneyQ43265105
Donor pre-treatment with everolimus or cyclosporine does not reduce ischaemia-reperfusion injury in a rat kidney transplant modelQ44068719
Protective effects of a potent C5a receptor antagonist on experimental acute limb ischemia-reperfusion in ratsQ44734358
Preoperative statin treatment reduces systemic inflammatory response and myocardial damage in cardiac surgery.Q45938003
Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cellsQ46314249
Predominant inhibition of interleukin-6 synthesis in patient-specific endothelial cells by mTOR inhibitors below a concentration range where cell proliferation is affected and mitotic arrest takes placeQ46420426
Prevention of atherosclerosis by the mTOR inhibitor everolimus in LDLR-/- mice despite severe hypercholesterolemiaQ46916538
Plasma interleukin-10 levels and adverse outcomes in acute coronary syndrome.Q48823158
Perioperative serum levels of tumour-necrosis-factor alpha (TNF-alpha), IL-1 beta, IL-6, IL-10 and soluble IL-2 receptor in patients undergoing cardiac surgery with cardiopulmonary bypass without and with correction for haemodilution.Q51434203
Preconditioning donor with a combination of tacrolimus and rapamacyn to decrease ischaemia-reperfusion injury in a rat syngenic kidney transplantation model.Q53201792
Chemokine CCL5/RANTES inhibition reduces myocardial reperfusion injury in atherosclerotic mice.Q53378752
Effect of rapamycin on the expression of the IL-2 receptor (CD25)Q70909270
Rate of glycolysis during ischemia determines extent of ischemic injury and functional recovery after reperfusionQ72850594
An imbalance between glycolysis and glucose oxidation is a possible explanation for the detrimental effects of high levels of fatty acids during aerobic reperfusion of ischemic heartsQ72941484
Everolimus triggers cytokine release by macrophages: rationale for stents eluting everolimus and a glucocorticoidQ83466246
IL-1β and TNFα-initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritisQ84972123
P433issue5
P304page(s)1771-1782
P577publication date2016-07-29
P1433published inInflammationQ2560341
P1476titleModulation of Immunologic Response by Preventive Everolimus Application in a Rat CPB Model.
P478volume39

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cites work (P2860)
Q55480734Hydrogen-rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus-activated kinase 2/signal transducer and activator of transcription 3 signaling pathway.
Q92059551Targeting of cell-free DNA by DNase I diminishes endothelial dysfunction and inflammation in a rat model of cardiopulmonary bypass

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