PTP1B promotes aggressiveness of breast cancer cells by regulating PTEN but not EMT.

scientific article published on 27 July 2016

PTP1B promotes aggressiveness of breast cancer cells by regulating PTEN but not EMT. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S13277-016-5245-1
P698PubMed publication ID27465552

P2093author name stringQing Liu
Xia Zhang
Qian Chen
Yan Liang
Xue Liu
Xiu-Wu Bian
Xi-Long Zhao
Xian-Chao Zhang
Yi-Fang Ping
Xu-Gang Hu
Ti-Wei Fu
P2860cites workIdentification of protein-tyrosine phosphatase 1B as the major tyrosine phosphatase activity capable of dephosphorylating and activating c-Src in several human breast cancer cell linesQ24290329
Protein-tyrosine phosphatase 1B complexes with the insulin receptor in vivo and is tyrosine-phosphorylated in the presence of insulinQ24313509
Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literatureQ24652514
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Sox2 promotes tamoxifen resistance in breast cancer cellsQ34381786
Tackling the cancer stem cells - what challenges do they pose?Q34523263
Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasisQ34607187
Hypoxia and the extracellular matrix: drivers of tumour metastasisQ34820282
The two faces of PTP1B in cancerQ35005347
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Deletion of Protein Tyrosine Phosphatase 1B (PTP1B) Enhances Endothelial Cyclooxygenase 2 Expression and Protects Mice from Type 1 Diabetes-Induced Endothelial DysfunctionQ35606400
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An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in miceQ35698954
Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cellsQ35832975
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Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell PopulationQ36471425
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PTP1B expression is an independent positive prognostic factor in human breast cancerQ37377170
Breast cancer stem cells transition between epithelial and mesenchymal states reflective of their normal counterpartsQ37564312
Classification and prognosis of invasive breast cancer: from morphology to molecular taxonomyQ37740954
Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targetsQ38107451
Cancer stem cells and their vascular niche: Do they benefit from each other?Q38483195
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The PI3K/AKT Pathway as a Target for Cancer TreatmentQ38608907
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Whom to blame for metastasis, the epithelial-mesenchymal transition or the tumor microenvironment?Q38704653
Rab11-FIP2 promotes colorectal cancer migration and invasion by regulating PI3K/AKT/MMP7 signaling pathway.Q38801189
miR-663 Suppresses Oncogenic Function of CXCR4 in GlioblastomaQ38869719
SOX2 promotes tumor metastasis by stimulating epithelial-to-mesenchymal transition via regulation of WNT/β-catenin signal networkQ39173044
Effects of estrogen on the proportion of stem cells in the breast.Q39652970
HER2 FISH classification of equivocal HER2 IHC breast cancers with use of the 2013 ASCO/CAP practice guidelineQ39983856
ERβ1 inversely correlates with PTEN/PI3K/AKT pathway and predicts a favorable prognosis in triple-negative breast cancer.Q41674321
Identification of Bidentate Salicylic Acid Inhibitors of PTP1B.Q43242949
Molecular Pathways Mediating Metastases to the Brain via Epithelial-to-Mesenchymal Transition: Genes, Proteins, and Functional AnalysisQ48924768
Semaphorin-3F suppresses the stemness of colorectal cancer cells by inactivating Rac1.Q53226116
Expression patterns of stromal MMP-2 and tumoural MMP-2 and -9 are significant prognostic factors in invasive ductal carcinoma of the breast.Q53276495
Protein-tyrosine phosphatase 1B is required for HER2/Neu-induced breast cancer.Q53335960
Interrogating Endogenous Protein Phosphatase Activity with Rationally Designed Chemosensors.Q54233465
American society of clinical oncology/college of american pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer.Q55154696
SnapShot: The epithelial-mesenchymal transitionQ83767418
P433issue10
P304page(s)13479-13487
P577publication date2016-07-27
P1433published inTumor BiologyQ15757842
P1476titlePTP1B promotes aggressiveness of breast cancer cells by regulating PTEN but not EMT.
P478volume37

Reverse relations

cites work (P2860)
Q96946545Activation of tyrosine phosphatase PTP1B in pyramidal neurons impairs endocannabinoid signaling by tyrosine receptor kinase trkB and causes schizophrenia-like behaviors in mice
Q58695806NKX2-1-AS1 negatively regulates CD274/PD-L1, cell-cell interaction genes, and limits human lung carcinoma cell migration
Q55262820Protection against gamma-radiation injury by protein tyrosine phosphatase 1B.
Q60307276Synthesis of small peptide compounds, molecular docking, and inhibitory activity evaluation against phosphatases PTP1B and SHP2
Q64262684miR-206 inhibits cell proliferation, invasion, and migration by down-regulating PTP1B in hepatocellular carcinoma

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