A computational tool for the simulation and optimization of microbial strains accounting integrated metabolic/regulatory information

scientific article published on December 7, 2010

A computational tool for the simulation and optimization of microbial strains accounting integrated metabolic/regulatory information is …
instance of (P31):
scholarly articleQ13442814

External links are
P8978DBLP publication IDjournals/biosystems/VilacaRR11
P356DOI10.1016/J.BIOSYSTEMS.2010.11.012
P953full work available at URLhttps://api.elsevier.com/content/article/PII:S0303264710002145?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0303264710002145?httpAccept=text/xml
https://repositorium.sdum.uminho.pt/bitstream/1822/14326/1/BioSystems-regulPlugin-pubVersion.pdf
P698PubMed publication ID21144882
P5875ResearchGate publication ID49670848

P50authorIsabel RochaQ47449076
Miguel RochaQ56871204
P2093author name stringPaulo Vilaça
P2860cites workAn expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR)Q21194867
Structural and functional analysis of cellular networks with CellNetAnalyzerQ21202799
Evolutionary programming as a platform for in silico metabolic engineeringQ25257616
Analysis of optimality in natural and perturbed metabolic networksQ28213254
OptFlux: an open-source software platform for in silico metabolic engineeringQ28280084
Regulatory on/off minimization of metabolic flux changes after genetic perturbationsQ28769658
Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growthQ29397612
Quantitative prediction of cellular metabolism with constraint-based models: the COBRA ToolboxQ29615372
Optknock: a bilevel programming framework for identifying gene knockout strategies for microbial strain optimizationQ29616020
Integrating high-throughput and computational data elucidates bacterial networksQ30928624
Predicting essential components of signal transduction networks: a dynamic model of guard cell abscisic acid signalingQ33257261
The regulatory network of E. coli metabolism as a Boolean dynamical system exhibits both homeostasis and flexibility of responseQ33321940
Natural computation meta-heuristics for the in silico optimization of microbial strainsQ33387681
Logical modelling of regulatory networks with GINsim 2.3.Q33442155
AIBench: a rapid application development framework for translational research in biomedicineQ33521794
OptORF: Optimal metabolic and regulatory perturbations for metabolic engineering of microbial strainsQ33567324
Advances in flux balance analysisQ33973453
Regulation of Gene Expression in Flux Balance Models of MetabolismQ34101809
Genetic networks with canalyzing Boolean rules are always stableQ37693857
A genome-scale computational study of the interplay between transcriptional regulation and metabolismQ42801030
Identification of all steady states in large networks by logical analysis.Q51637962
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectmetabolismQ1057
regulation of gene expressionQ411391
modelling biological systemsQ4299308
P304page(s)435-441
P577publication date2010-12-07
P1433published inBioSystemsQ2025895
P1476titleA computational tool for the simulation and optimization of microbial strains accounting integrated metabolic/regulatory information
P478volume103

Reverse relations

cites work (P2860)
Q39412598BeReTa: a systematic method for identifying target transcriptional regulators to enhance microbial production of chemicals
Q39240999Gene knockout identification using an extension of Bees Hill Flux Balance Analysis
Q38082903Genome-scale bacterial transcriptional regulatory networks: reconstruction and integrated analysis with metabolic models
Q38859481Genome-scale metabolic models as platforms for strain design and biological discovery
Q28083571In Silico Constraint-Based Strain Optimization Methods: the Quest for Optimal Cell Factories
Q50923419In silico deletion of PtsG gene in Escherichia coli genome-scale model predicts increased succinate production from glycerol.
Q57788170In silico model-guided identification of transcriptional regulator targets for efficient strain design
Q50918693Model-aided atpE gene knockout strategy in Escherichia coli for enhanced succinic acid production from glycerol.
Q64117653OptRAM: In-silico strain design via integrative regulatory-metabolic network modeling

Search more.