| scholarly article | Q13442814 |
| P50 | author | Ida Schoultz | Q59163566 |
| P2093 | author name string | Peter Söderkvist | |
| Maria Lerm | |||
| Urban Sjöqvist | |||
| Johan D Söderholm | |||
| Curt Tysk | |||
| Leif Törkvist | |||
| Deepti Verma | |||
| Mats Fredrikson | |||
| Mikael Lördal | |||
| Jonas Halfvarsson | |||
| P2860 | cites work | Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease | Q22251069 |
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| A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease | Q22251291 | ||
| CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways | Q24291679 | ||
| Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome | Q24291856 | ||
| Subclinical intestinal inflammation: an inherited abnormality in Crohn’s disease relatives? | Q57267231 | ||
| Combined Evidence From Three Large British Association Studies Rejects TUCAN/CARD8 as an IBD Susceptibility Gene | Q57436229 | ||
| Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection | Q24292675 | ||
| Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes | Q24298360 | ||
| The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta | Q24305136 | ||
| NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder | Q24317771 | ||
| Molecular cloning of the interleukin-1 beta converting enzyme | Q24338607 | ||
| Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease | Q27860821 | ||
| Risk factors for inflammatory bowel disease in the general population | Q28186843 | ||
| Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease | Q28201834 | ||
| A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes | Q28237565 | ||
| Cryopyrin activates the inflammasome in response to toxins and ATP | Q28291313 | ||
| Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA | Q28504793 | ||
| Sex steroid regulation of macrophage migration inhibitory factor in normal and inflamed colon in the female rat | Q28573619 | ||
| A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 | Q29614873 | ||
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| TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer. | Q33951635 | ||
| Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. | Q33982897 | ||
| Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition | Q34262569 | ||
| TUCAN (CARD8) genetic variants and inflammatory bowel disease. | Q34572565 | ||
| The current future understanding of inflammatory bowel disease | Q35021166 | ||
| Sex differences in inflammatory cytokine production in hepatic ischemia-reperfusion | Q35574175 | ||
| CARD15/NOD2 gene variants are associated with familially occurring and complicated forms of Crohn's disease. | Q35595543 | ||
| Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease. | Q35597793 | ||
| Novel isoforms of the CARD8 (TUCAN) gene evade a nonsense mutation. | Q40021792 | ||
| Gene polymorphisms in the NALP3 inflammasome are associated with interleukin-1 production and severe inflammation: relation to common inflammatory diseases? | Q40425740 | ||
| No association of the CARD8 (TUCAN) c.30T>A (p.C10X) variant with Crohn's disease: a study in 3 independent European cohorts | Q43433871 | ||
| Crohn's disease in Olmsted County, Minnesota, 1940-1993: incidence, prevalence, and survival | Q44671543 | ||
| Gender differences in inflammatory proteins and pathways in seasonal allergic rhinitis. | Q45338459 | ||
| MDP-induced interleukin-1beta processing requires Nod2 and CIAS1/NALP3. | Q46238812 | ||
| Sex differences in monocyte expression of IL-6: role of autonomic mechanisms | Q46615420 | ||
| IL-1beta-mediated proinflammatory responses are inhibited by estradiol via down-regulation of IL-1 receptor type I in uterine epithelial cells | Q46792417 | ||
| Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs | Q47194063 | ||
| NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: evidence for genetic heterogeneity within Europe? | Q47363325 | ||
| Inflammatory bowel disease: etiology and pathogenesis | Q47899867 | ||
| Increasing incidences of inflammatory bowel disease and decreasing surgery rates in Copenhagen City and County, 2003-2005: a population-based study from the Danish Crohn colitis database. | Q50543867 | ||
| Crohn's disease | Q54165583 | ||
| Interleukin-1-receptor antagonist in the Muckle-Wells syndrome. | Q54806497 | ||
| No association between the TUCAN (CARD8) Cys10Stop mutation and inflammatory bowel disease in a large retrospective German and a clinically well-characterized Norwegian sample. | Q55043850 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Sweden | Q34 |
| Crohn's disease | Q1472 | ||
| inflammasome complex | Q412405 | ||
| P304 | page(s) | 1180-1188 | |
| P577 | publication date | 2009-03-24 | |
| P1433 | published in | The American Journal of Gastroenterology | Q7713501 |
| P1476 | title | Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men | |
| P478 | volume | 104 |
| Q89911603 | A New Risk Polymorphism rs10403848 of CARD8 Significantly Associated with Psoriasis Vulgaris in Northeastern China |
| Q48123279 | Activation of NLRP3 Inflammasome in Inflammatory Bowel Disease: Differences Between Crohn's Disease and Ulcerative Colitis |
| Q38990222 | An Overview of the Innate and Adaptive Immune System in Inflammatory Bowel Disease |
| Q37853361 | Antibiotic therapy in inflammatory bowel disease: a systematic review and meta-analysis. |
| Q44128971 | Association between CARD8 rs2043211 polymorphism and inflammatory bowel disease: a meta-analysis |
| Q40502550 | Association between functional NLRP3 polymorphisms and susceptibility to autoimmune and inflammatory diseases: a meta-analysis. |
| Q43850995 | Association of CARD8 with inflammatory bowel disease in Koreans |
| Q34139580 | Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome. |
| Q38167854 | Association of NLRP3 and CARD8 genetic polymorphisms with juvenile idiopathic arthritis in a Taiwanese population. |
| Q47795988 | Association of NLRP3 polymorphisms with susceptibility to primary gouty arthritis in a Chinese Han population |
| Q38902064 | Association study of CARD8 (p.C10X) and NLRP3 (p.Q705K) variants with rheumatoid arthritis in French and Tunisian populations. |
| Q34454685 | C10X polymorphism in the CARD8 gene is associated with bacteraemia |
| Q36490766 | CARD8 rs2043211 (p.C10X) polymorphism is not associated with disease susceptibility or cardiovascular events in Spanish rheumatoid arthritis patients |
| Q36073123 | Clinical relevance of single nucleotide polymorphisms within the entire NLRP3 gene in patients with major blunt trauma |
| Q34189287 | Common genetic variations in the NALP3 inflammasome are associated with delayed apoptosis of human neutrophils |
| Q35602532 | Cross talk between neuroregulatory molecule and monocyte: nerve growth factor activates the inflammasome |
| Q35009123 | Cytokine profile in a cohort of healthy blood donors carrying polymorphisms in genes encoding the NLRP3 inflammasome |
| Q28083490 | Death-associated protein kinase: A molecule with functional antagonistic duality and a potential role in inflammatory bowel disease (Review) |
| Q63975672 | Diverging inflammasome signals in tumorigenesis and potential targeting |
| Q57471143 | Environmental Factors Modify the Severity of Acute DSS Colitis in Caspase-11-Deficient Mice |
| Q57154899 | Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease |
| Q36131898 | Genetic Polymorphisms in Inflammasome-Dependent Innate Immunity among Pediatric Patients with Severe Renal Parenchymal Infections |
| Q58861069 | Genetic Variation in the Inflammasome and Atopic Dermatitis Susceptibility |
| Q37836189 | Genetic and molecular basis of inflammasome-mediated disease |
| Q57623459 | Genetic variants inCARD8but not inNLRP3are associated with ankylosing spondylitis |
| Q53154278 | Genetic variation and alterations of genes involved in NFκB/TNFAIP3- and NLRP3-inflammasome signaling affect susceptibility and outcome of colorectal cancer. |
| Q58182915 | Genetic variation in inflammasome genes is associated with outcome in bacterial meningitis |
| Q37582336 | Human gene variants linked to enhanced NLRP3 activity limit intramacrophage growth of Mycobacterium tuberculosis. |
| Q27026882 | Inflammasome in intestinal inflammation and cancer |
| Q47869519 | Inflammasome polymorphisms confer susceptibility to sporadic malignant melanoma |
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| Q41935570 | Inflammasomes in the Gut Mucosal Homeostasis |
| Q64987518 | Inflammasomes make the case for littermate-controlled experimental design in studying host-microbiota interactions. |
| Q34159861 | Innate immunity in the small intestine |
| Q38175027 | Interactions between Nod-Like Receptors and Intestinal Bacteria |
| Q40376774 | Interleukin-1 cytokines, inflammasomes, NOD-signalosomes and autoinflammation |
| Q27023724 | Intestinal barrier in inflammatory bowel disease |
| Q37914788 | Is metabolic stress a common denominator in inflammatory bowel disease? |
| Q41227561 | Is the CARD8 rs2043211 polymorphism associated with susceptibility to Crohn's disease? A meta-analysis |
| Q50163250 | Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn's disease |
| Q38072224 | Microparticles and their impact on intestinal immunity |
| Q38947693 | Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance. |
| Q34893991 | Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines. |
| Q37862153 | Mitochondria: Sovereign of inflammation? |
| Q26781311 | Mitochondrial dysfunction in inflammatory bowel disease |
| Q36956703 | NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis |
| Q64087589 | NLRP3 Inflammasome and Inflammatory Bowel Disease |
| Q54189192 | NLRP3 gene is associated with ulcerative colitis (UC), but not Crohn's disease (CD), in Chinese Han population. |
| Q37501923 | NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis |
| Q30497993 | NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis |
| Q36276373 | NLRP3 p.Q705K and CARD8 p.C10X single nucleotide polymorphisms are not associated with susceptibility to rheumatoid arthritis: a meta-analysis |
| Q57578989 | NLRP3gene polymorphisms in Iranian patients with recurrent aphthous stomatitis |
| Q38453895 | NOD-Like Receptors: Guardians of Intestinal Mucosal Barriers |
| Q40138574 | Next-generation sequencing and its initial applications for molecular diagnosis of systemic auto-inflammatory diseases. |
| Q42452257 | Overexpression of ATP-activated P2X7 receptors in the intestinal mucosa is implicated in the pathogenesis of Crohn's disease |
| Q40071267 | Periodic Fever with Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis Syndrome Is Associated with a CARD8 Variant Unable To Bind the NLRP3 Inflammasome. |
| Q33885843 | Polymorphism of NLRP3 Gene and Association with Susceptibility to Digestive Disorders in Rabbit |
| Q49915054 | Polymorphisms and expression of inflammasome genes are associated with the development and severity of rheumatoid arthritis in Brazilian patients |
| Q64092861 | Polymorphisms in CARD8 and NLRP3 are associated with extrapulmonary TB and poor clinical outcome in active TB in Ethiopia |
| Q37565584 | Q705K variant in NLRP3 gene confers protection against myocardial infarction in female individuals |
| Q38091387 | Research progress on the NLRP3 inflammasome and its role in the central nervous system |
| Q90205913 | Role of NLRP3 inflammasome in inflammatory bowel diseases |
| Q35144145 | Role of genetic alterations in the NLRP3 and CARD8 genes in health and disease |
| Q90258934 | Role of inflammasome regulation on immune modulators |
| Q38291767 | Role of inflammasomes in intestinal inflammation and Crohn's disease |
| Q41277920 | Single nucleotide polymorphism of toll-like receptor 4 (TLR4) is associated with juvenile spondyloarthritis in Croatian population. |
| Q36068286 | Sporadic colorectal cancer: microbial contributors to disease prevention, development and therapy |
| Q39351075 | Targeted-mitochondria antioxidants therapeutic implications in inflammatory bowel disease |
| Q34626609 | The CARD8 p.C10X mutation associates with a low anti-glycans antibody response in patients with Crohn's disease |
| Q37144338 | The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis. |
| Q31057510 | The Q705K polymorphism in NLRP3 is a gain-of-function alteration leading to excessive interleukin-1β and IL-18 production |
| Q37729538 | The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond |
| Q34163374 | The role of bacteria and pattern-recognition receptors in Crohn's disease. |
| Q27027809 | The role of innate immunity receptors in the pathogenesis of inflammatory bowel disease |
| Q37957867 | The role of the NLRP3 inflammasome in gout |
| Q27678234 | The structure of the CARD8 caspase-recruitment domain suggests its association with the FIIND domain and procaspases through adjacent surfaces |
| Q57296225 | Transcriptomic analysis reveals a controlling mechanism for NLRP3 and IL-17A in dextran sulfate sodium (DSS)-induced colitis |
| Q40508948 | Vitamin B6 Prevents IL-1β Protein Production by Inhibiting NLRP3 Inflammasome Activation |
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