Blockage of the sodium current in isolated single cells from rat ventricle with mexiletine and disopyramide.

scientific article published in May 1985

Blockage of the sodium current in isolated single cells from rat ventricle with mexiletine and disopyramide. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0022-2828(85)80051-1
P698PubMed publication ID2411942

P2093author name stringAkaike N
Yatani A
P433issue5
P304page(s)467-476
P577publication date1985-05-01
P1433published inJournal of Molecular and Cellular CardiologyQ2061932
P1476titleBlockage of the sodium current in isolated single cells from rat ventricle with mexiletine and disopyramide.
P478volume17

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cites work (P2860)
Q39684518Assessing use-dependent inhibition of the cardiac Na(+/-) current (I(Na)) in the PatchXpress automated patch clamp
Q90215315Cardiovascular pharmacology of K2P17.1 (TASK-4, TALK-2) two-pore-domain K+ channels
Q95323110Characterisation of mexiletine's translational therapeutic index for suppression of ischaemia-induced ventricular fibrillation in the rat isolated heart
Q35872072Electrophysiological effects of the combination of mexiletine and flecainide in guinea-pig ventricular fibres
Q46970835Inhibition of the fast sodium inward current in ventricular cardiomyocytes of rats and guinea pigs by a novel potent sodium channel blocking agent
Q42627092Interaction between external Na+ and mexiletine on Na+ channel in guinea-pig ventricular myocytes
Q71978013Mexiletine antagonizes effects of sotalol on QT interval duration and its proarrhythmic effects in a canine model of torsade de pointes
Q37977364Mexiletine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in the treatment of arrhythmias
Q41357726Nicorandil shortens action potential duration and antagonises the reduction of Vmax by lidocaine but not by disopyramide in guinea-pig papillary muscles
Q38464799On the relationship between block of the cardiac Na⁺ channel and drug-induced prolongation of the QRS complex
Q37365724Pharmacological targeting of long QT mutant sodium channels
Q69351456Sodium channel-blocking properties of flecainide, a class IC antiarrhythmic drug, in guinea-pig papillary muscles. An open channel blocker or an inactivated channel blocker
Q42848940The effect of drugs with ion channel‐blocking activity on the early embryonic rat heart
Q26823149The role of late I Na in development of cardiac arrhythmias
Q39613654Translation of flecainide- and mexiletine-induced cardiac sodium channel inhibition and ventricular conduction slowing from nonclinical models to clinical
Q42759890Use-dependent block of Na+ currents by mexiletine at the single channel level in guinea-pig ventricular myocytes

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