The fringe molecules induce endocrine differentiation in embryonic endoderm by activating cMyt1/cMyt3.

scientific article published on 27 April 2006

The fringe molecules induce endocrine differentiation in embryonic endoderm by activating cMyt1/cMyt3. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YDBIO.2006.04.456
P698PubMed publication ID16920096
P5875ResearchGate publication ID6868284

P2093author name stringJia Zhang
Guoqiang Gu
Ben Z Stanger
Yanwen Xu
Aizhen Zhao
Sui Wang
P2860cites workDiabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient miceQ24314353
Notch signaling controls multiple steps of pancreatic differentiationQ24569636
neurogenin3 is required for the development of the four endocrine cell lineages of the pancreasQ24647944
Efficient selection for high-expression transfectants with a novel eukaryotic vectorQ27860810
Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in DrosophilaQ28115115
Manic fringe and lunatic fringe modify different sites of the Notch2 extracellular region, resulting in different signaling modulationQ28188343
GDF11 modulates NGN3+ islet progenitor cell number and promotes beta-cell differentiation in pancreas developmentQ28293930
Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cellsQ28301584
Notch signalling controls pancreatic cell differentiationQ28504686
Lunatic fringe null female mice are infertile due to defects in meiotic maturationQ28506185
Myelin transcription factor 1 (Myt1) of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous systemQ28506882
The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreasQ28507673
Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1Q28509366
Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant miceQ28512351
Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreasQ59070691
Control of endodermal endocrine development by Hes-1Q28513574
Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine developmentQ28592848
Myt1 family recruits histone deacetylase to regulate neural transcriptionQ28592882
Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiationQ28594048
FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ developmentQ28594673
Insulin-promoter-factor 1 is required for pancreas development in miceQ29619695
ST18 is a breast cancer tumor suppressor gene at human chromosome 8q11.2.Q30032679
The ghrelin cell: a novel developmentally regulated islet cell in the human pancreas.Q30838986
Specification of motor neuron identity by the MNR2 homeodomain proteinQ31997246
Pancreas development and diabetesQ33665819
Pancreas: how to get there from the gut?Q33796338
Notch gene expression during pancreatic organogenesisQ33904634
Intercellular signals regulating pancreas development and functionQ34131171
Developmental biology of the pancreas.Q34197365
Glycosylation regulates Notch signalling.Q34271410
Gene regulatory factors in pancreatic developmentQ34286940
Signaling and transcriptional control of pancreatic organogenesisQ34801929
Gene expression cascades in pancreatic developmentQ35029666
Transcription factors in islet development and physiology: role of PDX-1 in beta-cell functionQ35778205
Antero-posterior patterning of the vertebrate digestive tract: 40 years after Nicole Le Douarin's PhD thesisQ36133425
The molecular basis and prospects in pancreatic developmentQ36234233
Development of the endocrine pancreasQ36253123
Opposing actions of Arx and Pax4 in endocrine pancreas developmentQ36336824
A possible role for the canonical Wnt pathway in endocrine cell development in chicksQ40406573
Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genesQ40423677
Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2.Q40862987
The beta cell transcription factors and development of the pancreasQ41496269
fringe, a Boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development.Q42694998
A role for hairy1 in regulating chick limb bud growthQ43814674
Signals from lateral plate mesoderm instruct endoderm toward a pancreatic fateQ44481992
Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreasQ47073395
Fgf10 maintains notch activation, stimulates proliferation, and blocks differentiation of pancreatic epithelial cellsQ47595930
lunatic fringe is an essential mediator of somite segmentation and patterningQ47741550
Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient miceQ47932670
X-MyT1, a Xenopus C2HC-type zinc finger protein with a regulatory function in neuronal differentiationQ48056539
Global expression analysis of gene regulatory pathways during endocrine pancreatic development.Q52096645
Motor neuron columnar fate imposed by sequential phases of Hox-c activity.Q52098449
Notch signaling: Fringe really is a glycosyltransferase.Q52165281
Fringe modulates Notch-ligand interactions.Q52194027
The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreasQ59069706
P433issue2
P407language of work or nameEnglishQ1860
P1104number of pages10
P304page(s)340-349
P577publication date2006-04-27
P1433published inDevelopmental BiologyQ3025402
P1476titleThe fringe molecules induce endocrine differentiation in embryonic endoderm by activating cMyt1/cMyt3.
P478volume297

Reverse relations

cites work (P2860)
Q40076706Cre reconstitution allows for DNA recombination selectively in dual-marker-expressing cells in transgenic mice
Q37326969Developmental biology of the pancreas: a comprehensive review
Q37620107Distinct cellular origins for serotonin-expressing and enterochromaffin-like cells in the gastric corpus
Q41976049Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas
Q28507900Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse
Q37145399MFng is dispensable for mouse pancreas development and function
Q37209534MafA is a dedicated activator of the insulin gene in vivo
Q37809242Molecular biology of pancreatic ductal adenocarcinoma progression: aberrant activation of developmental pathways
Q36906380Mouse pancreatic endocrine cell transcriptome defined in the embryonic Ngn3-null mouse
Q36710960Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation
Q42559388Ngn3(+) endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium
Q26771258Notch Signaling in Pancreatic Development
Q38135365Notch signaling in the pancreas: patterning and cell fate specification
Q37234161On the origin of the beta cell
Q33287045Preservation of proliferating pancreatic progenitor cells by Delta-Notch signaling in the embryonic chicken pancreas
Q36128454Zebrafish grainyhead-like1 is a common marker of different non-keratinocyte epidermal cell lineages, which segregate from each other in a Foxi3-dependent manner

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