RNA buffers the phase separation behavior of prion-like RNA binding proteins.

scientific article published on 12 April 2018

RNA buffers the phase separation behavior of prion-like RNA binding proteins. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1126/SCIENCE.AAR7366
P932PMC publication ID6091854
P698PubMed publication ID29650702

P50authorAnthony A. HymanQ573389
Young-Tae ChangQ8057843
Pavel TomancakQ30353666
Marcus JahnelQ56458210
Simon AlbertiQ57080091
Marc BickleQ58667739
Titus M FranzmannQ60732459
Ina PoserQ61093960
Sandra RizkQ61093961
Shovamayee MaharanaQ61093965
Jie WangQ61093967
Dimitrios K PapadopoulosQ84077879
Jared SterneckertQ39945535
P2093author name stringAndrey Pozniakovsky
Doris Richter
Lara Marrone
Jordina Guillén-Boixet
P2860cites workALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear importQ24630100
Mechanisms of FUS mutations in familial amyotrophic lateral sclerosisQ26749169
Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative diseaseQ26753190
A human interactome in three quantitative dimensions organized by stoichiometries and abundancesQ27936244
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosisQ28131672
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosisQ28236796
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6Q28236805
Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillizationQ28588090
Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism.Q30313887
Liquid phase condensation in cell physiology and diseaseQ47649585
Mutations in the 3' untranslated region of FUS causing FUS overexpression are associated with amyotrophic lateral sclerosis.Q48021519
Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31.Q48244919
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.Q53368534
RNA-selective, live cell imaging probes for studying nuclear structure and functionQ33247679
Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosisQ33649745
An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone functionQ33795104
Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLSQ33889532
Inhibition of TDP-43 aggregation by nucleic acid bindingQ34758540
The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamicsQ35740324
RNA transcription modulates phase transition-driven nuclear body assemblyQ36103176
Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypesQ36709139
Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron lossQ36906420
Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathiesQ37220481
RNA Controls PolyQ Protein Phase Transitions.Q37573060
The role of FUS gene variants in neurodegenerative diseasesQ38212812
Decoding ALS: from genes to mechanism.Q39004348
Biomolecular condensates: organizers of cellular biochemistryQ39146409
RNA targets of wild-type and mutant FET family proteinsQ39603230
Structural determinants of the cellular localization and shuttling of TDP-43.Q39924105
Paraspeckles: Where Long Noncoding RNA Meets Phase Separation.Q47242675
P433issue6391
P407language of work or nameEnglishQ1860
P921main subjectprion protein familyQ24724413
P304page(s)918-921
P577publication date2018-04-12
P1433published inScienceQ192864
P1476titleRNA buffers the phase separation behavior of prion-like RNA binding proteins
P478volume360

Reverse relations

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