MIR137 schizophrenia-associated locus controls synaptic function by regulating synaptogenesis, synapse maturation and synaptic transmission.

scientific article published on 4 April 2018

MIR137 schizophrenia-associated locus controls synaptic function by regulating synaptogenesis, synapse maturation and synaptic transmission. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/HMG/DDY089
P932PMC publication ID5961183
P698PubMed publication ID29635364

P50authorDanielle PosthumaQ21257977
Matthijs VerhageQ56905118
Frank KoopmansQ57700182
Ka Wan LiQ58974076
Lennart Niels CornelisseQ89881944
Patrick F. SullivanQ56249782
Jan Van WeeringQ42765515
P2093author name stringAugust B Smit
Kensuke Sakamoto
Kyoko Watanabe
Sven Stringer
Anke Hammerschlag
Enqi He
Frank den Oudsten
Miguel A Gonzalez Lozano
Stephanie N Giamberardino
P2860cites workmiR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cellsQ21245271
MicroRNAs: target recognition and regulatory functionsQ24609584
MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1Q24630616
A global reference for human genetic variationQ25909434
Neurotransmitter release: the last millisecond in the life of a synaptic vesicleQ26269845
Synaptic plasticity, neural circuits, and the emerging role of altered short-term information processing in schizophreniaQ26829347
The schizophrenia risk gene product miR-137 alters presynaptic plasticity.Q27312392
Genome-wide association study identifies five new schizophrenia lociQ28248384
Meta-analysis of the heritability of human traits based on fifty years of twin studiesQ28262090
Startle gating deficits in a large cohort of patients with schizophrenia: relationship to medications, symptoms, neurocognition, and level of functionQ28277266
The morphological and molecular nature of synaptic vesicle priming at presynaptic active zonesQ28506683
Munc18-1 expression levels control synapse recovery by regulating readily releasable pool sizeQ28513229
Developmental and activity-dependent miRNA expression profiling in primary hippocampal neuron culturesQ28534050
Synaptotagmin-1 Docks Secretory Vesicles to Syntaxin-1/SNAP-25 Acceptor ComplexesQ56992446
Poor P50 suppression among schizophrenia patients and their first-degree biological relativesQ46171371
MicroRNA-137 Controls AMPA-Receptor-Mediated Transmission and mGluR-Dependent LTD.Q48118147
Interdependence of PKC-dependent and PKC-independent pathways for presynaptic plasticityQ48198484
A neuroprotective role for microRNA miR-1000 mediated by limiting glutamate excitotoxicityQ48348498
A comprehensive review of the genetic and biological evidence supports a role for MicroRNA-137 in the etiology of schizophrenia.Q50015658
Identifying true protein complex constituents in interaction proteomics: the example of the DMXL2 protein complex.Q54503711
A brain-specific microRNA regulates dendritic spine developmentQ29614753
MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cellsQ29616080
limma powers differential expression analyses for RNA-sequencing and microarray studiesQ29617988
Potential Impact of miR-137 and Its Targets in SchizophreniaQ30454963
MicroRNA-223 is neuroprotective by targeting glutamate receptorsQ30528539
Extending the limits of quantitative proteome profiling with data-independent acquisition and application to acetaminophen-treated three-dimensional liver microtissues.Q30901756
Cross talk between microRNA and epigenetic regulation in adult neurogenesisQ33788417
The impact of MIR137 on dorsolateral prefrontal-hippocampal functional connectivity in healthy subjectsQ33923604
Transcriptome-wide discovery of microRNA binding sites in human brain.Q33940022
Properties of synchronous and asynchronous release during pulse train depression in cultured hippocampal neuronsQ33949457
Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humansQ34475541
Chemical transmission between rat sympathetic neurons and cardiac myocytes developing in microcultures: evidence for cholinergic, adrenergic, and dual-function neuronsQ35038309
MicroRNA regulation of homeostatic synaptic plasticityQ35105269
Schizophrenia miR-137 locus risk genotype is associated with dorsolateral prefrontal cortex hyperactivationQ35596962
Dopamine-regulated microRNA MiR-181a controls GluA2 surface expression in hippocampal neuronsQ35697823
Increased SNARE Protein-Protein Interactions in Orbitofrontal and Anterior Cingulate Cortices in SchizophreniaQ35761611
miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cellsQ35818683
The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteinsQ37060125
Gene expression elucidates functional impact of polygenic risk for schizophreniaQ37372402
Genomic analyses reveal broad impact of miR-137 on genes associated with malignant transformation and neuronal differentiation in glioblastoma cellsQ37505070
Transcriptional consequences of schizophrenia candidate miR-137 manipulation in human neural progenitor cellsQ37706529
Chromosome 1p21.3 microdeletions comprising DPYD and MIR137 are associated with intellectual disabilityQ38331099
The schizophrenia risk gene MIR137 acts as a hippocampal gene network node orchestrating the expression of genes relevant to nervous system development and function.Q38450466
Dysregulations of Synaptic Vesicle Trafficking in SchizophreniaQ38883878
Transcriptional targets of the schizophrenia risk gene MIR137.Q38979078
MIR137 variants identified in psychiatric patients affect synaptogenesis and neuronal transmission gene setsQ38989183
Sensory gating in schizophrenia: P50 and N100 gating in antipsychotic-free subjects at risk, first-episode, and chronic patientsQ40105455
Disruption of the microRNA 137 primary transcript results in early embryonic lethality in mice.Q42260728
Validation of schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 as miR-137 targetsQ45263643
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P4510describes a project that useslimmaQ112236343
P433issue11
P921main subjectschizophreniaQ41112
P304page(s)1879-1891
P577publication date2018-06-01
P1433published inHuman Molecular GeneticsQ2720965
P1476titleMIR137 schizophrenia-associated locus controls synaptic function by regulating synaptogenesis, synapse maturation and synaptic transmission.
P478volume27