The phosphatase PTPL1 is required for PTEN-mediated regulation of apical membrane size.

scientific article published on 26 March 2018

The phosphatase PTPL1 is required for PTEN-mediated regulation of apical membrane size. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.00102-18
P932PMC publication ID5974425
P698PubMed publication ID29581186

P2093author name stringJohannes L Bos
Anneke Post
Axel Rosendahl Huber
Fried J Zwartkruis
Lucas J M Bruurs
Mirjam C van der Net
Susan Zwakenberg
P2860cites workEpithelial cell polarity, stem cells and cancerQ37968480
Rewiring cell polarity signaling in cancerQ38196268
Organization and execution of the epithelial polarity programmeQ38197884
PTEN-PDZ domain interactions: binding of PTEN to PDZ domains of PTPN13.Q38275375
aPKC restricts the basolateral determinant PtdIns(3,4,5)P3 to the basal region.Q40019299
PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.Q40178894
Phosphatidylinositol-3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cellsQ40241493
Rescue of glandular dysmorphogenesis in PTEN-deficient colorectal cancer epithelium by PPARγ-targeted therapy.Q42326441
Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signalingQ45295673
Regulated and polarized PtdIns(3,4,5)P3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cellsQ47071826
PTEN controls junction lengthening and stability during cell rearrangement in epithelial tissueQ47072872
A FERM domain governs apical confinement of PTP-BL in epithelial cellsQ73036178
Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2Q22253866
The protein kinase C-related kinase PRK2 interacts with the protein tyrosine phosphatase PTP-BL via a novel PDZ domain binding motifQ24291236
A novel GTPase-activating protein for Rho interacts with a PDZ domain of the protein-tyrosine phosphatase PTPL1Q24313540
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseQ24322705
Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrinQ24676944
Cell-type specific roles for PTEN in establishing a functional retinal architectureQ27307816
Histopathology of genetically defined endometrial precancersQ28139645
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal nicheQ28239639
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTENQ28513537
Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD.Q34546258
Loss of Pten Disrupts the Thymic Epithelium and Alters Thymic FunctionQ35935634
ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarizationQ36102727
PDZ interactions regulate rapid turnover of the scaffolding protein EBP50 in microvilliQ36135269
PTEN is required to maintain luminal epithelial homeostasis and integrity in the adult mammary glandQ36395967
The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epitheliumQ36539705
Disruption of epithelial architecture caused by loss of PTEN or by oncogenic mutant p110α/PIK3CA but not by HER2 or mutant AKT1.Q36827924
PTPL1: a large phosphatase with a split personalityQ37081432
Tenets of PTEN tumor suppressionQ37154214
Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomesQ37215885
Interaction of E-cadherin and PTEN regulates morphogenesis and growth arrest in human mammary epithelial cellsQ37351516
Epithelial organization, cell polarity and tumorigenesisQ37904131
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P407language of work or nameEnglishQ1860
P577publication date2018-03-26
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleThe phosphatase PTPL1 is required for PTEN-mediated regulation of apical membrane size.

Reverse relations

cites work (P2860)
Q83226421Crumbs organizes the transport machinery by regulating apical levels of PI(4,5)P in
Q90677914Profilin-Mediated Actin Allocation Regulates the Growth of Epithelial Microvilli