| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1990Sci...250..776L |
| P356 | DOI | 10.1126/SCIENCE.2237428 |
| P8608 | Fatcat ID | release_sq7hu34bkjeelda5hnypua3mc4 |
| P698 | PubMed publication ID | 2237428 |
| P2093 | author name string | Lesser DR | |
| Jen-Jacobson L | |||
| Kurpiewski MR | |||
| P2860 | cites work | Structural features and hydration of d(C-G-C-G-A-A-T-T-A-G-C-G); a double helix containing two G.A mispairs | Q68113333 |
| P433 | issue | 4982 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 776-786 | |
| P577 | publication date | 1990-11-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | The energetic basis of specificity in the Eco RI endonuclease--DNA interaction. | |
| P478 | volume | 250 |
| Q44249816 | 16 Analysis of equilibrium and kinetic measurements to determine thermodynamic origins of stability and specificity and mechanism of formation of site-specific complexes between proteins and helical DNA |
| Q51057877 | 2'-O-methyl nucleotide modified DNA substrates influence the cleavage efficiencies of BamHI and BglII. |
| Q40411346 | 7-Deazapurine containing DNA: efficiency of c7GdTP, c7AdTP and c7ldTP incorporation during PCR amplification and protection from endodeoxyribonuclease hydrolysis |
| Q34189241 | 70% efficiency of bistate molecular machines explained by information theory, high dimensional geometry and evolutionary convergence |
| Q36165221 | 8-Oxoguanine Affects DNA Backbone Conformation in the EcoRI Recognition Site and Inhibits Its Cleavage by the Enzyme |
| Q51862126 | A case study of the dynamics of in vitro DNA evolution under constant selection pressure. |
| Q35761177 | A conserved sequence element in ribonuclease III processing signals is not required for accuratein vitroenzymatic cleavage |
| Q38297784 | A dodecapeptide comprising the extended chain-alpha 4 region of the restriction endonuclease EcoRI specifically binds to the EcoRI recognition site |
| Q51551846 | A high throughput molecular force assay for protein-DNA interactions. |
| Q38354422 | A microarray method to evaluate the effect of CA mispairs on the accuracy of BstUI restriction endonuclease |
| Q45155300 | A monomeric mutant of restriction endonuclease EcoRI nicks DNA without sequence specificity |
| Q35922410 | A new affinity reagent for the site-specific, covalent attachment of DNA to active-site nucleophiles: application to the EcoRI and RsrI restriction and modification enzymes |
| Q34361503 | A new assay for tRNA aminoacylation kinetics |
| Q35169323 | A new restriction endonuclease-based method for highly-specific detection of DNA targets from methicillin-resistant Staphylococcus aureus |
| Q39079503 | A real-time assay for monitoring nucleic acid cleavage by quadruplex formation |
| Q34056203 | Additive, cooperative and anti-cooperative effects between identity nucleotides of a tRNA |
| Q83288910 | Alteration of sequence specificity of the type II restriction endonuclease HincII through an indirect readout mechanism |
| Q43568272 | An approach to metal-assisted DNA base pairing: novel beta-C-nucleosides with a 2-aminophenol or a catechol as the nucleobase |
| Q37259090 | Analyzing the forces binding a restriction endonuclease to DNA using a synthetic nanopore |
| Q40504205 | Anthracycline antibiotic arugomycin binds in both grooves of the DNA helix simultaneously: an NMR and molecular modelling study |
| Q53957720 | Asn141 is essential for DNA recognition by EcoRI restriction endonuclease. |
| Q37215395 | Assessment of the optimization of affinity and specificity at protein-DNA interfaces |
| Q78862511 | Association of protein-DNA recognition complexes: electrostatic and nonelectrostatic effects |
| Q27934634 | Asymmetrical recognition and activity of the I-SceI endonuclease on its site and on intron-exon junctions |
| Q35805058 | Bacteriophage T2Dam and T4Dam DNA-[N6-adenine]-methyltransferases |
| Q74033453 | Bi-stranded, multisite replication of a base pair between difluorotoluene and adenine: confirmation by 'inverse' sequencing |
| Q35647707 | Binding and cleavage of DNA with the restriction enzyme EcoR1 using time-resolved second harmonic generation. |
| Q35906064 | Changes in solvation during DNA binding and cleavage are critical to altered specificity of the EcoRI endonuclease |
| Q34779319 | Characterization of Aquifex aeolicus ribonuclease III and the reactivity epitopes of its pre-ribosomal RNA substrates |
| Q37161414 | Cleavage of mispaired heteroduplex DNA substrates by numerous restriction enzymes. |
| Q40963622 | Counting the calories to stay in the groove. |
| Q38295631 | DNA binding and recognition by the IIs restriction endonuclease MboII. |
| Q34770269 | DNA determinants in sequence-specific recognition by XmaI endonuclease |
| Q37977119 | DNA methyltransferases: mechanistic models derived from kinetic analysis |
| Q38351325 | DNA recognition by the EcoRV restriction endonuclease probed using base analogues |
| Q48011893 | DNA-protein interactions under random jump conditions |
| Q24801031 | DNA-tension dependence of restriction enzyme activity reveals mechanochemical properties of the reaction pathway |
| Q42154543 | Detecting SNPs using a synthetic nanopore |
| Q37083042 | Determinant nucleotides of yeast tRNA(Asp) interact directly with aspartyl-tRNA synthetase |
| Q34187355 | Differences between EcoRI nonspecific and "star" sequence complexes revealed by osmotic stress |
| Q38309095 | Differences in hydration coupled to specific and nonspecific competitive binding and to specific DNA Binding of the restriction endonuclease BamHI. |
| Q37232952 | Differences in water release for the binding of EcoRI to specific and nonspecific DNA sequences |
| Q33618211 | Diffusion of the restriction nuclease EcoRI along DNA. |
| Q37698622 | Diversity of DNA methyltransferases that recognize asymmetric target sequences |
| Q34139821 | Do mRNA and rRNA binding sites of E.coli ribosomal protein S15 share common structural determinants? |
| Q35921953 | ESR spectroscopy identifies inhibitory Cu2+ sites in a DNA-modifying enzyme to reveal determinants of catalytic specificity |
| Q38327472 | Effect of tetrahydropyrimidine derivatives on protein-nucleic acids interaction. Type II restriction endonucleases as a model system |
| Q35032359 | Effects of 2'-O-methyl nucleotide substitution on EcoRI endonuclease cleavage activities |
| Q34362106 | Effects of oligonucleotide length and atomic composition on stimulation of the ATPase activity of translation initiation factor elF4A. |
| Q41970720 | Electron spin resonance shows common structural features for different classes of EcoRI-DNA complexes |
| Q27683352 | Elimination of inter-domain interactions increases the cleavage fidelity of the restriction endonuclease DraIII |
| Q32084623 | Endonuclease II of coliphage T4: a recombinase disguised as a restriction endonuclease? |
| Q33268780 | Energetics of the protein-DNA-water interaction |
| Q37238334 | Engineering variants of the I-SceI homing endonuclease with strand-specific and site-specific DNA-nicking activity |
| Q43095726 | Escherichia coli DNA adenine methyltransferase: the structural basis of processive catalysis and indirect read-out |
| Q34620085 | Experimental and theoretical high pressure strategies for investigating protein-nucleic acid assemblies |
| Q47994680 | Experimental measurement of binding energy, selectivity, and allostery using fluctuation theorems |
| Q36477020 | Facilitated distortion of the DNA site enhances EcoRI endonuclease-DNA recognition |
| Q42095907 | Factors responsible for target site selection in Tn10 transposition: a role for the DDE motif in target DNA capture. |
| Q42930937 | Fluorescent marker for direct detection of specific dsDNA sequences |
| Q33427689 | Footprinting of EcoRI endonuclease at high pressure |
| Q40150469 | Free energy calculations and molecular dynamics simulations of wild-type and variants of the DNA-EcoRI complex |
| Q51641693 | Free-energy component analysis of 40 protein-DNA complexes: a consensus view on the thermodynamics of binding at the molecular level. |
| Q38334936 | Functional interaction of hybrid response elements with wild-type and mutant steroid hormone receptors |
| Q48456322 | High affinity DNA-microtubule associated protein interaction |
| Q43247619 | How PspGI, catalytic domain of EcoRII and Ecl18kI acquire specificities for different DNA targets |
| Q67887690 | Importance of oligoelectrolyte end effects for the thermodynamics of conformational transitions of nucleic acid oligomers: A grand canonical Monte Carlo analysis |
| Q38287780 | Importance of phosphate contacts for sequence recognition by EcoRI restriction enzyme |
| Q42618349 | In vivo restriction. Sequence and structure of endonuclease II-dependent cleavage sites in bacteriophage T4 DNA |
| Q35935233 | In vivo specificity of EcoRI DNA methyltransferase |
| Q42876257 | Increasing cleavage specificity and activity of restriction endonuclease KpnI. |
| Q34684612 | Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: recognition of pyrimidine-purine and purine-purine steps |
| Q30443011 | Influence of enzyme-substrate contacts located outside the EcoRI recognition site on cleavage of duplex oligodeoxyribonucleotide substrates by EcoRI endonuclease |
| Q38359134 | Influence of the phosphate backbone on the recognition and hydrolysis of DNA by the EcoRV restriction endonuclease. A study using oligodeoxynucleotide phosphorothioates |
| Q43786814 | Inhibitory module of Ets-1 allosterically regulates DNA binding through a dipole-facilitated phosphate contact |
| Q35149934 | Insights into copper coordination in the EcoRI-DNA complex by ESR spectroscopy. |
| Q38296377 | Investigation of DNA-protein sequence-specific interactions with a ds-DNA array. |
| Q36762427 | Investigation of the mechanisms of DNA binding of the human G/T glycosylase using designed inhibitors |
| Q73636278 | Kinetic analysis of the coordinated interaction of SgrAI restriction endonuclease with different DNA targets |
| Q33182315 | Kinetics of binding of Hoechst dyes to DNA studied by stopped-flow fluorescence techniques |
| Q24812802 | Kinetics of substrate recognition and cleavage by human 8-oxoguanine-DNA glycosylase |
| Q34630862 | Labeling DNA for single-molecule experiments: methods of labeling internal specific sequences on double-stranded DNA |
| Q41077325 | Linear diffusion of the restriction endonuclease EcoRV on DNA is essential for the in vivo function of the enzyme |
| Q52383200 | MONTY: a Monte Carlo approach to protein-DNA recognition. |
| Q73947952 | Macromolecular hydration changes associated with BamHI binding and catalysis |
| Q36909769 | Massively parallel characterization of restriction endonucleases |
| Q34320524 | Microarray-based fluorescence assay of endonuclease functionality and inhibition |
| Q38295434 | Modified nucleotides reveal the indirect role of the central base pairs in stabilizing the lac repressor-operator complex |
| Q27641370 | Modulation of the Active Complex Assembly and Turnover Rate by Protein−DNA Interactions in Cre−LoxP Recombination † , ‡ |
| Q33924377 | Molecular diagnostics for personal medicine using a nanopore |
| Q38302062 | Molecular dynamics simulations suggest that the Eco RI kink is an example of molecular strain |
| Q33938573 | Multiple levels of affinity-dependent DNA discrimination in Cre-LoxP recombination |
| Q52530957 | Mutational analysis of the function of Met137 and Ile197, two amino acids implicated in sequence-specific DNA recognition by the EcoRI endonuclease. |
| Q34590601 | Mutations in an RNP1 consensus sequence of Rho protein reduce RNA binding affinity but facilitate helicase turnover |
| Q34143828 | Naphthalene, Phenanthrene, and Pyrene as DNA Base Analogues: Synthesis, Structure, and Fluorescence in DNA |
| Q27666491 | New clues in the allosteric activation of DNA cleavage bySgrAI: structures ofSgrAI bound to cleaved primary-site DNA and uncleaved secondary-site DNA |
| Q27641830 | Nucleotide shuffling and ssDNA recognition in Oxytricha nova telomere end-binding protein complexes |
| Q31007129 | On the catalytic mechanism of EcoRI and EcoRV. A detailed proposal based on biochemical results, structural data and molecular modelling |
| Q57135737 | Osmotic pressure effects on EcoRV cleavage and binding |
| Q42392599 | Positively charged C-terminal subdomains of EcoRV endonuclease: contributions to DNA binding, bending, and cleavage |
| Q34362145 | Probing the TRAP-RNA interaction with nucleoside analogs |
| Q24811023 | Protein-DNA binding specificity predictions with structural models |
| Q36469373 | Protein-DNA complexes: the cost of recognition |
| Q47678791 | Protein-DNA force assay in a microfluidic format |
| Q38323342 | Quantifying DNA-protein interactions by double-stranded DNA arrays. |
| Q77387617 | RNA structure inhibits the TRAP (trp RNA-binding attenuation protein)-RNA interaction |
| Q30862585 | Rapid identification of key amino-acid-DNA contacts through combinatorial peptide synthesis |
| Q72891182 | Receptor-specific desensitization of the S49 lymphoma cell adenylyl cyclase. Unaltered behavior of the regulatory component |
| Q33304888 | Recognition of essential purines by the U1A protein |
| Q34187086 | Restriction endonucleases: classification, properties, and applications |
| Q38295212 | Saturation mutagenesis of His114 of EcoRI reveals relaxed-specificity mutants |
| Q34008473 | Self-generated DNA termini relax the specificity of SgrAI restriction endonuclease |
| Q36936967 | Sensitive Cu2+-Cu2+ distance measurements in a protein-DNA complex by double-quantum coherence ESR. |
| Q38297419 | Sequence-specific DNA recognition by the SmaI endonuclease |
| Q36834032 | Short-range and long-range context effects on coliphage T4 endonuclease II-dependent restriction |
| Q36365194 | Simple Biophysical Model Predicts Faster Accumulation of Hybrid Incompatibilities in Small Populations Under Stabilizing Selection |
| Q30414084 | Simulating the dynamics and orientations of spin-labeled side chains in a protein-DNA complex. |
| Q41464146 | Single molecule high-throughput footprinting of small and large DNA ligands |
| Q42552306 | Single-molecule sequence detection via microfluidic planar extensional flow at a stagnation point |
| Q52357194 | Site-specific dynamics in DNA: theory and experiment. |
| Q36740088 | Snap-to-it probes: chelate-constrained nucleobase oligomers with enhanced binding specificity |
| Q35164408 | Solution parameters modulating DNA binding specificity of the restriction endonuclease EcoRV. |
| Q27765958 | Solution structure of a DNA duplex containing a replicable difluorotoluene-adenine pair |
| Q38308094 | Specificity of DNA binding and methylation by the M.FokI DNA methyltransferase |
| Q44741670 | Specificity of protein-DNA recognition revealed by structure-based potentials: symmetric/asymmetric and cognate/non-cognate binding |
| Q35076163 | Stabilizing labile DNA-protein complexes in polyacrylamide gels |
| Q35926930 | Strong DNA binding by covalently linked dimeric Lac headpiece: evidence for the crucial role of the hinge helices |
| Q35851462 | Structural adaptations in the interaction of EcoRI endonuclease with methylated GAATTC sites. |
| Q27649010 | Structural and Thermodynamic Basis for Enhanced DNA Binding by a Promiscuous Mutant EcoRI Endonuclease |
| Q27625226 | Structure of BamHI bound to nonspecific DNA: a model for DNA sliding |
| Q40150434 | Structure, interaction, dynamics and solvent effects on the DNA-EcoRI complex in aqueous solution from molecular dynamics simulation |
| Q58611623 | Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI |
| Q36005819 | Structure-based prediction of the stability of transmembrane helix-helix interactions: the sequence dependence of glycophorin A dimerization |
| Q39689707 | Substitution of an essential adenine in the U1A-RNA complex with a non-polar isostere |
| Q36536632 | Substrate-assisted catalysis in the cleavage of DNA by the EcoRI and EcoRV restriction enzymes |
| Q36223085 | T7 RNA polymerase mutants with altered promoter specificities |
| Q43141069 | Targeting individual subunits of the FokI restriction endonuclease to specific DNA strands |
| Q90287145 | The Need for Speed: Run-On Oligomer Filament Formation Provides Maximum Speed with Maximum Sequestration of Activity |
| Q67731871 | The activity of the EcoRV restriction endonuclease is influenced by flanking DNA sequences both inside and outside the DNA-protein complex |
| Q43457408 | The affinity of DNA-microtubule protein complexes and their disruption by tubulin binding drugs |
| Q38313890 | The dissociation rate of the EcoRI-DNA-specific complex is linked to water activity |
| Q42060631 | The energetic contribution of induced electrostatic asymmetry to DNA bending by a site-specific protein |
| Q34363328 | The mechanism of RNA binding to TRAP: initiation and cooperative interactions. |
| Q30459862 | The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2. |
| Q90578947 | The run-on oligomer filament enzyme mechanism of SgrAI: Part 2. Kinetic modeling of the full DNA cleavage pathway |
| Q37592534 | Thermodynamic and structural basis for relaxation of specificity in protein-DNA recognition |
| Q38335880 | Thermodynamic, kinetic and structural basis for recognition and repair of abasic sites in DNA by apurinic/apyrimidinic endonuclease from human placenta. |
| Q36618352 | Thermodynamics of sequence-specific protein-DNA interactions. |
| Q36825372 | Transition state for protein-DNA recognition |
| Q47264926 | Two-step interrogation then recognition of DNA binding site by Integration Host Factor: an architectural DNA-bending protein |
| Q34996805 | Type II restriction endonucleases |
| Q33843093 | Type II restriction endonucleases--a historical perspective and more |
| Q93177828 | Unique mechanism of target recognition by PfoI restriction endonuclease of the CCGG-family |
| Q35040989 | Using a structural and logics systems approach to infer bHLH-DNA binding specificity determinants |
| Q42211325 | Variola type IB DNA topoisomerase: DNA binding and supercoil unwinding using engineered DNA minicircles |
| Q37695269 | Water release associated with specific binding of gal repressor |
| Q34361045 | Yeast ribosomal protein L32 recognizes an RNA G:U juxtaposition |
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