Impact of two novel mutations on the structure and function of human myeloperoxidase.

scientific article published on 24 July 2007

Impact of two novel mutations on the structure and function of human myeloperoxidase. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M701984200
P698PubMed publication ID17650507

P2093author name stringWilliam M Nauseef
Yosuke Kameoka
Kazuo Suzuki
Artem Cherkasov
Kevin G Leidal
Meilan Huang
Joshua M Astern
Melissa Goedken
Sally McCormick
P2860cites workEffect of the R569W missense mutation on the biosynthesis of myeloperoxidaseQ24336913
X-ray crystal structure and characterization of halide-binding sites of human myeloperoxidase at 1.8 A resolutionQ27622235
X-ray crystal structure of canine myeloperoxidase at 3 A resolutionQ27642075
All-atom empirical potential for molecular modeling and dynamics studies of proteinsQ27860468
Human myeloperoxidase and thyroid peroxidase, two enzymes with separate and distinct physiological functions, are evolutionarily related members of the same gene familyQ28281160
Calreticulin functions as a molecular chaperone in the biosynthesis of myeloperoxidaseQ28610241
Myeloperoxidase: friend and foeQ29619070
Reaction of myeloperoxidase compound I with chloride, bromide, iodide, and thiocyanate.Q31919165
Biosynthesis, processing, and sorting of human myeloperoxidaseQ33223927
Quality control in the endoplasmic reticulum: lessons from hereditary myeloperoxidase deficiencyQ33731035
Active site structure and catalytic mechanisms of human peroxidasesQ33991456
Impact of missense mutations on biosynthesis of myeloperoxidaseQ34037721
Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to oxidize alpha-amino acids to a family of reactive aldehydes. Mechanistic studies identifying labile intermediates along the reaction pathwayQ34066009
Assembly of the phagocyte NADPH oxidaseQ34338562
Autocatalytic radical reactions in physiological prosthetic heme modificationQ35150165
Biochemical and immunologic analysis of hereditary myeloperoxidase deficiencyQ35206808
Characterization of cDNA clones for human myeloperoxidase: predicted amino acid sequence and evidence for multiple mRNA speciesQ36120246
Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activationQ36207505
Human neutrophils employ chlorine gas as an oxidant during phagocytosisQ37359571
A novel form of hereditary myeloperoxidase deficiency linked to endoplasmic reticulum/proteasome degradationQ37383836
Characterization and quantification of the peroxidase in human monocytesQ39207271
Role of heme-protein covalent bonds in mammalian peroxidases. Protection of the heme by a single engineered heme-protein link in horseradish peroxidaseQ40285136
NADPH oxidase of neutrophilsQ40976674
The role of the propeptide for processing and sorting of human myeloperoxidaseQ41059058
Structural and biological properties of human recombinant myeloperoxidase produced by Chinese hamster ovary cell linesQ41684451
Purification and some properties of myeloperoxidase and eosinophil peroxidase from human bloodQ42105803
Human neutrophils employ myeloperoxidase to convert alpha-amino acids to a battery of reactive aldehydes: a pathway for aldehyde generation at sites of inflammationQ42542698
Prosthetic heme modification during halide ion oxidation. Demonstration of chloride oxidation by horseradish peroxidaseQ44616896
Novel missense mutation found in a Japanese patient with myeloperoxidase deficiencyQ44774506
Genetic characterization of myeloperoxidase deficiency in ItalyQ44860243
Autocatalytic processing of heme by lactoperoxidase produces the native protein-bound prosthetic group.Q46031301
Heme-protein covalent bonds in peroxidases and resistance to heme modification during halide oxidationQ46327802
A sensitive and selective assay for chloramine production by myeloperoxidaseQ46794251
Purification and characterization of small molecular weight myeloperoxidase from human promyelocytic leukemia HL-60 cellsQ47284811
Role of heme in intracellular trafficking of thyroperoxidase and involvement of H2O2 generated at the apical surface of thyroid cells in autocatalytic covalent heme bindingQ47851581
Vascular endothelial growth factor (VEGF) is suppressed in WT1-transfected LNCaP cells.Q52569623
Chloramines as intermediates of oxidation reaction of amino acids by myeloperoxidase.Q53870899
A theoretical three-dimensional model for lactoperoxidase and eosinophil peroxidase, built on the scaffold of the myeloperoxidase X-ray structureQ56564884
P433issue38
P407language of work or nameEnglishQ1860
P304page(s)27994-28003
P577publication date2007-07-24
P1433published inJournal of Biological ChemistryQ867727
P1476titleImpact of two novel mutations on the structure and function of human myeloperoxidase.
P478volume282

Reverse relations

cites work (P2860)
Q50167687Biosynthesis of human myeloperoxidase
Q36666229Conserved cysteine residues provide a protein-protein interaction surface in dual oxidase (DUOX) proteins.
Q34166052Functional consequence of positive selection revealed through rational mutagenesis of human myeloperoxidase
Q41198350Perturbed Heme Binding Is Responsible for the Blistering Phenotype Associated with Mutations in the Caenorhabditis elegans Dual Oxidase 1 (DUOX1) Peroxidase Domain
Q36282271Proconvertase proteolytic processing of an enzymatically active myeloperoxidase precursor
Q30372838Rational drug design applied to myeloperoxidase inhibition.
Q33705499Structure of human promyeloperoxidase (proMPO) and the role of the propeptide in processing and maturation
Q35927277T47D Cells Expressing Myeloperoxidase Are Able to Process, Traffic and Store the Mature Protein in Lysosomes: Studies in T47D Cells Reveal a Role for Cys319 in MPO Biosynthesis that Precedes Its Known Role in Inter-Molecular Disulfide Bond Formation
Q35135142The role of insulin-like growth factor-I in the physiopathology of hearing.
Q41116769Unraveling the genes implicated in Alzheimer's disease
Q36228801Vascular peroxidase-1 is rapidly secreted, circulates in plasma, and supports dityrosine cross-linking reactions

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