The MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development.

scientific article published on 19 March 2018

The MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development. is …
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scholarly articleQ13442814

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P819ADS bibcode2018NatCo...9.1139S
P356DOI10.1038/S41467-018-03576-3
P932PMC publication ID5859096
P698PubMed publication ID29556010

P50authorMark J ButtnerQ55764039
Tung Bk LeQ57025563
Richard G BrennanQ63371375
Matthew BushQ42425218
P2093author name stringChris D den Hengst
Maria A Schumacher
Govind Chandra
Ngat T Tran
Wenjie Zeng
Brady Travis
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Structure of the Staphylococcus aureus AgrA LytTR Domain Bound to DNA Reveals a Beta Fold with an Unusual Mode of BindingQ27650551
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The bldC developmental locus of Streptomyces coelicolor encodes a member of a family of small DNA-binding proteins related to the DNA-binding domains of the MerR family.Q30775239
SmeA, a small membrane protein with multiple functions in Streptomyces sporulation including targeting of a SpoIIIE/FtsK-like protein to cell division septaQ33297912
Probing direct interactions between CodY and the oppD promoter of Lactococcus lactisQ33699680
The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.Q33878469
Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development.Q34121159
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The competence transcription factor of Bacillus subtilis recognizes short A/T-rich sequences arranged in a unique, flexible pattern along the DNA helixQ35200591
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Structural basis of the mercury(II)-mediated conformational switching of the dual-function transcriptional regulator MerRQ36002447
Structural and Dynamics Characterization of the MerR Family Metalloregulator CueR in its Repression and Activation States.Q50960400
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A response regulator-like protein that functions at an intermediate stage of sporulation in Streptomyces coelicolor A3(2)Q73189488
Proteins encoded by the conservon of Streptomyces coelicolor A3(2) comprise a membrane-associated heterocomplex that resembles eukaryotic G protein-coupled regulatory systemQ79327901
The Ser/Thr protein kinase AfsK regulates polar growth and hyphal branching in the filamentous bacteria StreptomycesQ36212849
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Structural Analysis of the Hg(II)-Regulatory Protein Tn501 MerR from Pseudomonas aeruginosaQ37264608
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c-di-GMP signalling and the regulation of developmental transitions in streptomycetes.Q38616129
Multi-layered inhibition of Streptomyces development: BldO is a dedicated repressor of whiB.Q41040019
One of the two genes encoding nucleoid-associated HU proteins in Streptomyces coelicolor is developmentally regulated and specifically involved in spore maturationQ42095648
Web 3DNA--a web server for the analysis, reconstruction, and visualization of three-dimensional nucleic-acid structuresQ42173686
Recognition of 5'-YpG-3' sequences by coupled stacking/hydrogen bonding interactions with amino acid residuesQ44691235
The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminusQ44777466
The Streptomyces O-B one connection: a force within layered repression of a key developmental decision.Q48042280
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that useslimmaQ112236343
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)1139
P577publication date2018-03-19
P1433published inNature CommunicationsQ573880
P1476titleThe MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development
P478volume9

Reverse relations

cites work (P2860)
Q64274689BldC Delays Entry into Development To Produce a Sustained Period of Vegetative Growth in Streptomyces venezuelae
Q92407164Cryo-EM structure of a type I-F CRISPR RNA guided surveillance complex bound to transposition protein TniQ
Q90057977Crystal structure of an Escherichia coli Hfq Core (residues 2-69)-DNA complex reveals multifunctional nucleic acid binding sites
Q58106096DNA mapping and kinetic modeling of the HrdB regulon in Streptomyces coelicolor
Q92681138Metal sensing and regulation of adaptive responses to manganese limitation by MtsR is critical for group A streptococcus virulence

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