T cell mediated immunity induced by the live-attenuated Shigella flexneri 2a vaccine candidate CVD 1208S in humans.

scientific article published on 13 March 2018

T cell mediated immunity induced by the live-attenuated Shigella flexneri 2a vaccine candidate CVD 1208S in humans. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1101525895
P356DOI10.1186/S12967-018-1439-1
P932PMC publication ID5851169
P698PubMed publication ID29534721

P50authorMyron M. LevineQ29564379
Karen L KotloffQ63214788
P2093author name stringFranklin R Toapanta
Marcelo B Sztein
Paula J Bernal
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CD44 isoforms containing exons V6 and V7 are differentially expressed on mitogenically stimulated normal and Epstein-Barr virus-transformed human B cellsQ41304163
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Shigella flexneri 2a strain CVD 1207, with specific deletions in virG, sen, set, and guaBA, is highly attenuated in humansQ34003433
Gut-Homing Conventional Plasmablasts and CD27(-) Plasmablasts Elicited after a Short Time of Exposure to an Oral Live-Attenuated Shigella Vaccine Candidate in HumansQ34068059
Initial steps of Shigella infection depend on the cholesterol/sphingolipid raft-mediated CD44-IpaB interactionQ34091098
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Ex Vivo kinetics of early and long-term multifunctional human leukocyte antigen E-specific CD8+ cells in volunteers immunized with the Ty21a typhoid vaccine.Q34150391
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Epstein-barr virus-induced changes in B-lymphocyte gene expressionQ34347958
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IFNγ inhibits the cytosolic replication of Shigella flexneri via the cytoplasmic RNA sensor RIG-I.Q34388456
Local entrapment of interferon gamma in the recovery from Shigella dysenteriae type 1 infection.Q34409399
Expansion of pathogen-specific mono- and multifunctional Th1 and Th17 cells in multi-focal tuberculous lymphadenitisQ34603041
Persistence of local cytokine production in shigellosis in acute and convalescent stages.Q35380946
Activation of Salmonella Typhi-specific regulatory T cells in typhoid disease in a wild-type S. Typhi challenge modelQ35637207
Oral Wild-Type Salmonella Typhi Challenge Induces Activation of Circulating Monocytes and Dendritic Cells in Individuals Who Develop Typhoid DiseaseQ35660952
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Salmonella Typhi-specific multifunctional CD8+ T cells play a dominant role in protection from typhoid fever in humansQ36634226
Shigella's ways of manipulating the host intestinal innate and adaptive immune system: a tool box for survival?Q36703588
Shigella antigen-specific B memory cells are associated with decreased disease severity in subjects challenged with wild-type Shigella flexneri 2a.Q36920244
Antigen-specific B memory cell responses to lipopolysaccharide (LPS) and invasion plasmid antigen (Ipa) B elicited in volunteers vaccinated with live-attenuated Shigella flexneri 2a vaccine candidatesQ37120727
Inflammatory mediator ultra-low-molecular-weight hyaluronan triggers necrosis of B-precursor leukemia cells with high surface CD44 expression.Q38676263
Deletion in the Shigella enterotoxin genes further attenuates Shigella flexneri 2a bearing guanine auxotrophy in a phase 1 trial of CVD 1204 and CVD 1208.Q39146446
CD4 CTL, a Cytotoxic Subset of CD4+ T Cells, Their Differentiation and Function.Q39172071
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Induction of necrosis in human neutrophils by Shigella flexneri requires type III secretion, IpaB and IpaC invasins, and actin polymerizationQ39514537
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P433issue1
P921main subjectShigella flexneriQ1644417
attenuated vaccineQ1810913
P304page(s)61
P577publication date2018-03-13
P1433published inJournal of Translational MedicineQ15716664
P1476titleT cell mediated immunity induced by the live-attenuated Shigella flexneri 2a vaccine candidate CVD 1208S in humans.
P478volume16

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cites work (P2860)
Q57929967A Novel Proteome Microarray Discriminates Targets of Human Antibody Reactivity following Oral Vaccination and Experimental Challenge
Q57924523Characterization of a serologically atypical Shigella flexneri Z isolated from diarrheal patients in Bangladesh and a proposed serological scheme for Shigella flexneri
Q92968346Role of antigen specific T and B cells in systemic and mucosal immune responses in ETEC and Shigella infections, and their potential to serve as correlates of protection in vaccine development
Q64244181Screening for coeliac disease in children and adults living in a slum of Dhaka, Bangladesh

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