Gut-Homing Conventional Plasmablasts and CD27(-) Plasmablasts Elicited after a Short Time of Exposure to an Oral Live-Attenuated Shigella Vaccine Candidate in Humans

scientific article

Gut-Homing Conventional Plasmablasts and CD27(-) Plasmablasts Elicited after a Short Time of Exposure to an Oral Live-Attenuated Shigella Vaccine Candidate in Humans is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3389/FIMMU.2014.00374
P932PMC publication ID4138503
P698PubMed publication ID25191323
P5875ResearchGate publication ID265391573

P50authorMyron M. LevineQ29564379
Marcela F. PasettiQ56380831
Karen L KotloffQ63214788
P2093author name stringFranklin R Toapanta
Marcelo B Sztein
Eileen M Barry
Jakub K Simon
P2860cites workElucidation of seventeen human peripheral blood B-cell subsets and quantification of the tetanus response using a density-based method for the automated identification of cell populations in multidimensional flow cytometry dataQ24605194
High endothelial venules (HEVs): specialized endothelium for lymphocyte migrationQ28288508
Systems biology approach predicts immunogenicity of the yellow fever vaccine in humansQ29616204
Characterization of B-cell epitopes on IpaB, an invasion-associated antigen of Shigella flexneri: identification of an immunodominant domain recognized during natural infectionQ33608118
Expression of homing receptors on IgA1 and IgA2 plasmablasts in blood reflects differential distribution of IgA1 and IgA2 in various body fluidsQ33725110
Global burden of Shigella infections: implications for vaccine development and implementation of control strategiesQ33749510
Differences in immune responses induced by oral and rectal immunizations with Salmonella typhi Ty21a: evidence for compartmentalization within the common mucosal immune system in humansQ33768258
Dengue virus activates polyreactive, natural IgG B cells after primary and secondary infectionQ34117580
Phase I evaluation of delta virG Shigella sonnei live, attenuated, oral vaccine strain WRSS1 in healthy adultsQ34120926
Intestinal IgA synthesis: regulation of front-line body defencesQ34168492
Peak frequencies of circulating human influenza-specific antibody secreting cells correlate with serum antibody response after immunizationQ34205800
Heterogeneity of multifunctional IL-17A producing S. Typhi-specific CD8+ T cells in volunteers following Ty21a typhoid immunizationQ34297117
Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control studyQ34345075
Impact of oral typhoid vaccination on the human gut microbiota and correlations with s. Typhi-specific immunological responsesQ34700862
Antigen-specific IgA B memory cell responses to Shigella antigens elicited in volunteers immunized with live attenuated Shigella flexneri 2a oral vaccine candidates.Q34809879
Systems biology of vaccination for seasonal influenza in humansQ35118722
Environmental cues, dendritic cells and the programming of tissue-selective lymphocyte traffickingQ35208814
Plasma-cell homingQ35549150
Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1.Q41541656
Functionally Distinct Subpopulations of CpG-Activated Memory B Cells.Q42030999
Diverse phosphorylation patterns of B cell receptor-associated signaling in naïve and memory human B cells revealed by phosphoflow, a powerful technique to study signaling at the single cell levelQ42421045
Studies on vaccination against bacillary dysentery. 3. Effective oral immunization against Shigella flexneri 2a in a field trialQ42982958
Human immune responses to influenza virus vaccines administered by systemic or mucosal routesQ45772716
Blood-borne human plasma cells in steady state are derived from mucosal immune responsesQ46262153
Homing potentials of circulating lymphocytes in humans depend on the site of activation: oral, but not parenteral, typhoid vaccination induces circulating antibody-secreting cells that all bear homing receptors directing them to the gut.Q50135778
Prevention of shigellosis by a Salmonella typhi-Shigella sonnei bivalent vaccineQ50201269
Immunogenicity of Ty21a attenuated "Salmonella typhi" given with sodium bicarbonate or in enteric-coated capsules.Q50212585
Studies in volunteers to evaluate candidate Shigella vaccines: further experience with a bivalent Salmonella typhi-Shigella sonnei vaccine and protection conferred by previous Shigella sonnei disease.Q50464343
Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response.Q51996837
Expression of GlyCAM-1, an endothelial ligand for L-selectin, is affected by afferent lymphatic flow.Q52220993
Regulation of CXCR3 and CXCR4 expression during terminal differentiation of memory B cells into plasma cells.Q52940412
A modified Shigella volunteer challenge model in which the inoculum is administered with bicarbonate buffer: clinical experience and implications for Shigella infectivity.Q54158784
Double-blind vaccine-controlled randomised efficacy trial of an investigational Shigella sonnei conjugate vaccine in young adults.Q54572055
Cloning, expression, and affinity purification of recombinant Shigella flexneri invasion plasmid antigens IpaB and IpaC.Q54576324
Effect of prior infection with virulent Shigella flexneri 2a on the resistance of monkeys to subsequent infection with Shigella sonneiQ67941446
Serum antibodies to lipopolysaccharide and natural immunity to shigellosis in an Israeli military populationQ68134308
Mucosally activated circulating human B cells in diarrhea express homing receptors directing them back to the gutQ71035571
Safety and immunogenicity of CVD 1208S, a live, oral DeltaguaBA Deltasen Deltaset Shigella flexneri 2a vaccine grown on animal-free mediaQ81445405
Shigellosis: innate mechanisms of inflammatory destruction of the intestinal epithelium, adaptive immune response, and vaccine developmentQ35696566
Persistence of diarrheal pathogens is associated with continued recruitment of plasmablasts in the circulationQ35726077
Lymphocyte trafficking across high endothelial venules: dogmas and enigmasQ35762431
Rapid and massive virus-specific plasmablast responses during acute dengue virus infection in humansQ35826280
Peroral ciprofloxacin therapy impairs the generation of a protective immune response in a mouse model for Salmonella enterica serovar Typhimurium diarrhea, while parenteral ceftriaxone therapy does not.Q35941385
Live oral typhoid vaccine Ty21a induces cross-reactive humoral immune responses against Salmonella enterica serovar Paratyphi A and S. Paratyphi B in humansQ36017715
Lymphocyte homing to the gut: attraction, adhesion, and commitmentQ36209695
Monoclonal immunoglobulin A antibody directed against serotype-specific epitope of Shigella flexneri lipopolysaccharide protects against murine experimental shigellosisQ36365336
The intestinal chemokine thymus-expressed chemokine (CCL25) attracts IgA antibody-secreting cellsQ36369860
Shigella's ways of manipulating the host intestinal innate and adaptive immune system: a tool box for survival?Q36703588
Studies on vaccination against bacillary dysentery. 6. Protection of children by oral immunization with streptomycin-dependent Shigella strainsQ36720620
Clinical trials of Shigella vaccines: two steps forward and one step back on a long, hard roadQ36844719
Shigella antigen-specific B memory cells are associated with decreased disease severity in subjects challenged with wild-type Shigella flexneri 2a.Q36920244
Indirect measurement of intestinal immune responses to an orally administered attenuated bacterial vaccineQ36945363
Prospective study of systemic and mucosal immune responses in dysenteric patients to specific Shigella invasion plasmid antigens and lipopolysaccharides.Q36966451
Serum immune response to Shigella protein antigens in rhesus monkeys and humans infected with Shigella sppQ37010733
Adjuvanted intranasal Norwalk virus-like particle vaccine elicits antibodies and antibody-secreting cells that express homing receptors for mucosal and peripheral lymphoid tissuesQ37044185
Circulating human antibody-secreting cells during vaccinations and respiratory viral infections are characterized by high specificity and lack of bystander effectQ37053088
Progress and pitfalls in Shigella vaccine researchQ37105553
Antigen-specific B memory cell responses to lipopolysaccharide (LPS) and invasion plasmid antigen (Ipa) B elicited in volunteers vaccinated with live-attenuated Shigella flexneri 2a vaccine candidatesQ37120727
Presence of specific immunoglobulin A-secreting cells in peripheral blood after natural infection with Shigella sonneiQ37125747
Key developmental transitions in human germinal center B cells are revealed by differential CD45RB expressionQ37169139
Differentiation and homing of IgA-secreting cellsQ37349705
Differential expression of tissue-specific adhesion molecules on human circulating antibody-forming cells after systemic, enteric, and nasal immunizations. A molecular basis for the compartmentalization of effector B cell responsesQ37365152
Dendritic cells in intestinal homeostasis and disease.Q37591719
Update on mucosal immunoglobulin A in gastrointestinal diseaseQ37778711
Shigella are versatile mucosal pathogens that circumvent the host innate immune system.Q37901683
Origin and Function of Circulating Plasmablasts during Acute Viral InfectionsQ38008373
Deletion in the Shigella enterotoxin genes further attenuates Shigella flexneri 2a bearing guanine auxotrophy in a phase 1 trial of CVD 1204 and CVD 1208.Q39146446
Epidemiologic patterns of acute diarrhea and endemic Shigella infections in children in a poor periurban setting in Santiago, ChileQ39252440
Intransal or intragastric immunization with proteosome-Shigella lipopolysaccharide vaccines protects against lethal pneumonia in a murine model of Shigella infectionQ39822312
Chemistry and immunochemistry of bacterial lipopolysaccharides as cell wall antigens and endotoxinsQ40105951
Plasmablast-derived polyclonal antibody response after influenza vaccinationQ40339871
Rotavirus-specific B cells induced by recent infection in adults and children predominantly express the intestinal homing receptor alpha4beta7.Q40613333
Evaluation of the safety, immunogenicity, and efficacy in healthy adults of four doses of live oral hybrid Escherichia coli-Shigella flexneri 2a vaccine strain EcSf2a-2Q40687041
An early humoral immune response in peripheral blood following parenteral inactivated influenza vaccinationQ41024287
Shigellosis: from molecular pathogenesis of infection to protective immunity and vaccine developmentQ41452318
Production of IFN-gamma and IL-10 to Shigella invasins by mononuclear cells from volunteers orally inoculated with a Shiga toxin-deleted Shigella dysenteriae type 1 strainQ41480678
Semiquantitative estimation of Shigella antigen-specific antibodies: correlation with disease severity during shigellosisQ41490859
P921main subjectattenuated vaccineQ1810913
P304page(s)374
P577publication date2014-08-20
P1433published inFrontiers in ImmunologyQ27723748
P1476titleGut-Homing Conventional Plasmablasts and CD27(-) Plasmablasts Elicited after a Short Time of Exposure to an Oral Live-Attenuated Shigella Vaccine Candidate in Humans
P478volume5

Reverse relations

cites work (P2860)
Q90621575A Phase 1 dose escalating study of double mutant heat-labile toxin LTR192G/L211A (dmLT) from Enterotoxigenic Escherichia coli (ETEC) by sublingual or oral immunization
Q93367325Diminished B-Cell Response After Repeat Influenza Vaccination
Q50652449Induction of long term mucosal immunological memory in humans by an oral inactivated multivalent enterotoxigenic Escherichia coli vaccine.
Q36051755Oral Challenge with Wild-Type Salmonella Typhi Induces Distinct Changes in B Cell Subsets in Individuals Who Develop Typhoid Disease
Q37477191Shigella Vaccine Development: Finding the Path of Least Resistance
Q52657631T cell mediated immunity induced by the live-attenuated Shigella flexneri 2a vaccine candidate CVD 1208S in humans.

Search more.