Shigella Vaccine Development: Finding the Path of Least Resistance

scientific article published on 05 October 2016

Shigella Vaccine Development: Finding the Path of Least Resistance is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/CVI.00444-16
P932PMC publication ID5139600
P698PubMed publication ID27707764

P50authorKaren L KotloffQ63214788
P2093author name stringWilbur H Chen
P2860cites workDecline of Childhood Haemophilus influenzae Type b (Hib) Disease in the Hib Vaccine EraQ22253018
Use of quantitative molecular diagnostic methods to identify causes of diarrhoea in children: a reanalysis of the GEMS case-control studyQ30275836
Association Between Shigella Infection and Diarrhea Varies Based on Location and Age of ChildrenQ30278777
Pathogen-specific burdens of community diarrhoea in developing countries: a multisite birth cohort study (MAL-ED).Q30278967
Synthesis, characterization, and clinical evaluation of conjugate vaccines composed of the O-specific polysaccharides of Shigella dysenteriae type 1, Shigella flexneri type 2a, and Shigella sonnei (Plesiomonas shigelloides) bound to bacterial toxoidQ33607442
Vaccination against shigellosis with attenuated Shigella flexneri 2a strain SC602Q33876803
Strategy for cross-protection among Shigella flexneri serotypesQ34000330
Safety and immunogenicity of improved Shigella O-specific polysaccharide-protein conjugate vaccines in adults in IsraelQ34006223
Gut-Homing Conventional Plasmablasts and CD27(-) Plasmablasts Elicited after a Short Time of Exposure to an Oral Live-Attenuated Shigella Vaccine Candidate in HumansQ34068059
Phase I evaluation of delta virG Shigella sonnei live, attenuated, oral vaccine strain WRSS1 in healthy adultsQ34120926
Shigella isolates from the global enteric multicenter study inform vaccine developmentQ34202171
Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control studyQ34345075
Status of vaccine research and development for ShigellaQ34518265
Head-to-head comparison of humoral immune responses to Vi capsular polysaccharide and Salmonella Typhi Ty21a typhoid vaccines--a randomized trialQ34673466
Safety and immunogenicity of investigational Shigella conjugate vaccines in Israeli volunteersQ35523144
South Asia as a Reservoir for the Global Spread of Ciprofloxacin-Resistant Shigella sonnei: A Cross-Sectional StudyQ36092436
Studies on vaccination against bacillary dysentery. 6. Protection of children by oral immunization with streptomycin-dependent Shigella strainsQ36720620
Evaluation of the Safety, Tolerability, and Immunogenicity of an Oral, Inactivated Whole-Cell Shigella flexneri 2a Vaccine in Healthy Adult SubjectsQ36764372
Clinical trials of Shigella vaccines: two steps forward and one step back on a long, hard roadQ36844719
Shigella antigen-specific B memory cells are associated with decreased disease severity in subjects challenged with wild-type Shigella flexneri 2a.Q36920244
Parenteral Vaccination Can Be an Effective Means of Inducing Protective Mucosal ResponsesQ36973944
Circulating Gut-Homing (α4β7+) Plasmablast Responses against Shigella Surface Protein Antigens among Hospitalized Patients with DiarrheaQ37067264
Clinical Trial of an Oral Live Shigella sonnei Vaccine Candidate, WRSS1, in Thai AdultsQ37067290
Progress and pitfalls in Shigella vaccine researchQ37105553
Safety and Immunogenicity of a Candidate Bioconjugate Vaccine against Shigella flexneri 2a Administered to Healthy Adults: a Single-Blind, Randomized Phase I Study.Q37477196
Inactivated and subunit vaccines to prevent shigellosisQ37640115
Polysaccharide-protein conjugates: a new generation of vaccinesQ37914157
Recent progress towards development of a Shigella vaccineQ38068954
The estimated mortality impact of vaccinations forecast to be administered during 2011-2020 in 73 countries supported by the GAVI Alliance.Q38100050
An assessment of enterotoxigenic Escherichia coli and Shigella vaccine candidates for infants and childrenQ38284501
Characterization of a multicomponent live, attenuated Shigella flexneri vaccineQ38776163
Global, regional, and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: an updated systematic analysisQ39119101
Deletion in the Shigella enterotoxin genes further attenuates Shigella flexneri 2a bearing guanine auxotrophy in a phase 1 trial of CVD 1204 and CVD 1208.Q39146446
Epidemiologic patterns of acute diarrhea and endemic Shigella infections in children in a poor periurban setting in Santiago, ChileQ39252440
Prospective study of the association between serum antibodies to lipopolysaccharide O antigen and the attack rate of shigellosisQ40211202
Perspective: hypothesis: serum IgG antibody is sufficient to confer protection against infectious diseases by inactivating the inoculumQ40538332
Safety and immunogenicity of Shigella sonnei-CRM9 and Shigella flexneri type 2a-rEPAsucc conjugate vaccines in one- to four-year-old childrenQ40552513
Evaluation of the safety, immunogenicity, and efficacy in healthy adults of four doses of live oral hybrid Escherichia coli-Shigella flexneri 2a vaccine strain EcSf2a-2Q40687041
Purification and characterization of a Shigella conjugate vaccine, produced by glycoengineering Escherichia coliQ41008205
Studies on vaccination against bacillary dysentery. 3. Effective oral immunization against Shigella flexneri 2a in a field trialQ42982958
Recommendations regarding the development of combined enterotoxigenic Eschericha coli and Shigella vaccines for infantsQ48669093
Studies in volunteers to evaluate candidate Shigella vaccines: further experience with a bivalent Salmonella typhi-Shigella sonnei vaccine and protection conferred by previous Shigella sonnei disease.Q50464343
Safety, dose, immunogenicity, and transmissibility of an oral live attenuated Shigella flexneri 2a vaccine candidate (SC602) among healthy adults and school children in Matlab, Bangladesh.Q51745561
Live oral Shigella vaccine: vaccination schedule and the effect of booster dose.Q54362925
Double-blind vaccine-controlled randomised efficacy trial of an investigational Shigella sonnei conjugate vaccine in young adults.Q54572055
Age-related efficacy of Shigella O-specific polysaccharide conjugates in 1-4-year-old Israeli children.Q64948328
Reduction of oropharyngeal carriage of Haemophilus influenzae type b (Hib) in children immunized with an Hib conjugate vaccineQ68043029
Serum antibodies to lipopolysaccharide and natural immunity to shigellosis in an Israeli military populationQ68134308
Safety and immunogenicity of Shigella sonnei and Shigella flexneri 2a O-specific polysaccharide conjugates in childrenQ77399559
Safety and immunogenicity of CVD 1208S, a live, oral DeltaguaBA Deltasen Deltaset Shigella flexneri 2a vaccine grown on animal-free mediaQ81445405
P433issue12
P304page(s)904-907
P577publication date2016-10-05
P1433published inClinical and Vaccine ImmunologyQ5133811
P1476titleShigella Vaccine Development: Finding the Path of Least Resistance
P478volume23

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cites work (P2860)
Q49210830A Phase 2a Randomized Study to Evaluate the Safety and Immunogenicity of the 1790GAHB Generalized Modules for Membrane Antigen Vaccine against Shigella sonnei Administered Intramuscularly to Adults from a Shigellosis-Endemic Country
Q64996406A murine model of diarrhea, growth impairment and metabolic disturbances with Shigella flexneri infection and the role of zinc deficiency.
Q92801042Characterization and immunogenicity of a Shigella flexneri 2a O-antigen bioconjugate vaccine candidate
Q99616537Establishment of a Controlled Human Infection Model with a Lyophilized Strain of Shigella sonnei 53G
Q90441881Increasing the affinity of an O-antigen polysaccharide binding site in Shigella flexneri bacteriophage Sf6 tailspike protein

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