Spliced integrated retrotransposed element (SpIRE) formation in the human genome.

scientific article published on 5 March 2018

Spliced integrated retrotransposed element (SpIRE) formation in the human genome. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PBIO.2003067
P932PMC publication ID5860796
P698PubMed publication ID29505568

P2093author name stringJohn B Moldovan
John V Moran
Christine R Beck
Jeffrey M Kidd
Naveen Jasti
Peter A Larson
P2860cites workThe human L1 promoter: variable transcription initiation sites and a major impact of upstream flanking sequence on promoter activityQ40299427
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LINE-1 retrotransposition requires the nucleic acid chaperone activity of the ORF1 proteinQ46434712
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Full-length human L1 insertions retain the capacity for high frequency retrotransposition in cultured cellsQ47948394
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L1 family of repetitive DNA sequences in primates may be derived from a sequence encoding a reverse transcriptase-related proteinQ56905068
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Apolipoprotein(a) gene enhancer resides within a LINE elementQ74016300
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Human l1 retrotransposition is associated with genetic instability in vivoQ74604697
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Identification and solution structure of a highly conserved C-terminal domain within ORF1p required for retrotransposition of long interspersed nuclear element-1Q27645863
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Retrotransposition and Crystal Structure of an Alu RNP in the Ribosome-Stalling ConformationQ27702648
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Human L1 retrotransposon encodes a conserved endonuclease required for retrotranspositionQ28114795
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Point mutations close to the AUG initiator codon affect the efficiency of translation of rat preproinsulin in vivoQ28272278
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Mammalian small nucleolar RNAs are mobile genetic elementsQ28469078
The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu RetrotranspositionQ28547090
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LINE-1 elements in structural variation and diseaseQ28654758
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LINE-1 retrotransposition activity in human genomesQ28743798
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Defining the beginning and end of KpnI family segmentsQ33939728
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Poly(A) binding protein C1 is essential for efficient L1 retrotransposition and affects L1 RNP formationQ36362853
Two additional potential retrotransposons isolated from a human L1 subfamily that contains an active retrotransposable elementQ36416853
L1 retrotransposition requires rapid ORF1p oligomerization, a novel coiled coil-dependent property conserved despite extensive remodelingQ36443314
The impact of multiple splice sites in human L1 elementsQ36515503
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Many human L1 elements are capable of retrotranspositionQ36859141
A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancerQ36959154
A YY1-binding site is required for accurate human LINE-1 transcription initiationQ37346150
Transduction-specific ATLAS reveals a cohort of highly active L1 retrotransposons in human populationsQ37433509
Studies on p40, the leucine zipper motif-containing protein encoded by the first open reading frame of an active human LINE-1 transposable elementQ38325406
The Mobile Element Locator Tool (MELT): Population-scale mobile element discovery and biologyQ38601704
LINE-1 Cultured Cell Retrotransposition AssayQ38792667
Nucleic acid chaperone activity of the ORF1 protein from the mouse LINE-1 retrotransposonQ39457323
Determination of L1 retrotransposition kinetics in cultured cellsQ39586006
Discrete subcellular partitioning of human retrotransposon RNAs despite a common mechanism of genome insertionQ39741192
Efficient translation initiation directed by the 900-nucleotide-long and GC-rich 5' untranslated region of the human retrotransposon LINE-1 mRNA is strictly cap dependent rather than internal ribosome entry site mediatedQ40139032
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)e2003067
P577publication date2018-03-05
P1433published inPLOS BiologyQ1771695
P1476titleSpliced integrated retrotransposed element (SpIRE) formation in the human genome.
P478volume16

Reverse relations

cites work (P2860)
Q64076955Dynamic Methylation of an L1 Transduction Family during Reprogramming and Neurodifferentiation
Q92102903Identification and characterization of occult human-specific LINE-1 insertions using long-read sequencing technology
Q55692166L1 retrotransposition in the soma: a field jumping ahead.
Q96640370Measuring and interpreting transposable element expression
Q52673987Reading the tea leaves: Dead transposon copies reveal novel host and transposon biology.
Q91712521The UCSC repeat browser allows discovery and visualization of evolutionary conflict across repeat families
Q64112074The impact of transposable element activity on therapeutically relevant human stem cells

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