Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy.

scientific article published on 19 April 2018

Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1006956
P932PMC publication ID5908070
P698PubMed publication ID29672640

P50authorHans-Peter KiemQ88408730
Jacob D EstesQ90263659
Claire DeleageQ90797291
Shiu-Lok HuQ56933191
Keith R. JeromeQ57904630
Meei-Li HuangQ61713476
P2093author name stringJasbir Kaur
Michael C Holmes
Jianbin Wang
Andreas Reik
Patricia Polacino
Christopher W Peterson
Sowmya Reddy
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Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIVQ28235281
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Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantationQ28300338
Immune activation, CD4+ T cell counts, and viremia exhibit oscillatory patterns over time in patients with highly resistant HIV infectionQ28478654
Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIVQ28551642
Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantationQ29615068
Antiretroviral-free HIV-1 remission and viral rebound after allogeneic stem cell transplantation: report of 2 casesQ34539993
B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllersQ35058635
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Strategies for the identification of T cell-recognized tumor antigens in hematological malignancies for improved graft-versus-tumor responses after allogeneic blood and marrow transplantationQ35588845
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Lack of viral control and development of combination antiretroviral therapy escape mutations in macaques after bone marrow transplantationQ36067042
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Persistent Simian Immunodeficiency Virus Infection Drives Differentiation, Aberrant Accumulation, and Latent Infection of Germinal Center Follicular T Helper CellsQ36481555
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Long-term reduction in peripheral blood HIV type 1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantationQ36796554
Persistent HIV-1 replication maintains the tissue reservoir during therapyQ36897321
Long-term multilineage engraftment of autologous genome-edited hematopoietic stem cells in nonhuman primatesQ36920437
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Defining HIV and SIV Reservoirs in Lymphoid Tissues.Q37090999
Robust suppression of env-SHIV viremia in Macaca nemestrina by 3-drug ART is independent of timing of initiation during chronic infectionQ37169285
HIV DNA Is Frequently Present within Pathologic Tissues Evaluated at Autopsy from Combined Antiretroviral Therapy-Treated Patients with Undetectable Viral Loads.Q37300347
HIV Maintains an Evolving and Dispersed Population in Multiple Tissues during Suppressive Combined Antiretroviral Therapy in Individuals with Cancer.Q37300442
Where does HIV hide? A focus on the central nervous systemQ37590425
Effect of HIV Antibody VRC01 on Viral Rebound after Treatment InterruptionQ37624842
The majority of CD4+ T-cell depletion during acute simian-human immunodeficiency virus SHIV89.6P infection occurs in uninfected cellsQ37643739
Loss of immune homeostasis dictates SHIV rebound after stem-cell transplantationQ37661792
Reduced-intensity hematopoietic stem cell transplants for malignancies: harnessing the graft-versus-tumor effectQ38057359
Is the CCR5 Δ 32 mutation associated with immune system-related diseases?Q38068379
Donor lymphocyte infusions in AML and MDS: Enhancing the graft-versus-leukemia effectQ39059436
Engineering HIV-Resistant, Anti-HIV Chimeric Antigen Receptor T CellsQ40351372
Broadly Neutralizing Antibodies for HIV-1 Prevention or ImmunotherapyQ40411834
Novel benzamides as selective and potent gastric prokinetic agents. 1. Synthesis and structure-activity relationships of N-[(2-morpholinyl)alkyl]benzamidesQ42148874
The role of a mutant CCR5 allele in HIV-1 transmission and disease progression.Q43521980
Sensitivity of hematological malignancies to graft-versus-host effects: an EBMT megafile analysisQ44477645
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Allogeneic haematopoietic stem cell transplantation: individualized stem cell and immune therapy of cancerQ48881552
The Delta 32 mutation of the chemokine-receptor 5 gene neither is correlated with chronic hepatitis C nor does it predict response to therapy with interferon-alpha and ribavirin.Q50582759
P275copyright licenseCreative Commons CC0 LicenseQ6938433
P6216copyright statuscopyrighted, dedicated to the public domain by copyright holderQ88088423
P433issue4
P921main subjectgene therapyQ213901
P304page(s)e1006956
P577publication date2018-04-19
P1433published inPLOS PathogensQ283209
P1476titleDifferential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy
P478volume14

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Q90707628Curing HIV: Seeking to Target and Clear Persistent Infection
Q99637221Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo
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Q60951107Gene Editing of HIV-1 Co-receptors to Prevent and/or Cure Virus Infection
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