Contribution of Sp1 to Telomerase Expression and Activity in Skin Keratinocytes Cultured With a Feeder Layer (scientific article published in February 2015)

Sp1 and Sp3 recruit histone deacetylase to repress transcription of human telomerase reverse transcriptase (hTERT) promoter in normal human somatic cells

Q28216580

Myc activates telomerase

Q28505489

Telomeres shorten during ageing of human fibroblasts

Q29547357

Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells

Q29614425

Structure and function of telomeres

Q29615759

Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair

Q33818854

Stable association of hsp90 and p23, but Not hsp70, with active human telomerase

Q33939931

The telomere hypothesis of cellular aging

Q33973605

Growth of cultured human epidermal cells into multiple epithelia suitable for grafting

Q33979849

Can we produce a human corneal equivalent by tissue engineering?

Q33990087

Telomerase is controlled by protein kinase Calpha in human breast cancer cells

Q34068018

Telomerase and human tumorigenesis

Q34136624

Lipid composition and synthesis of HaCaT cells, an immortalized human keratinocyte line, in comparison with normal human adult keratinocytes

Q34339815

Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes

Q34387542

The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

Q34687302

Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

Q34724924

Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells.

Q35190791

Location and clonal analysis of stem cells and their differentiated progeny in the human ocular surface.

Q36256645

Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibility

Q36568052

Transduction of E2F-1 TAT fusion proteins represses expression of hTERT in primary ductal breast carcinoma cell lines

Q36593473

Association of hsp90 to the hTERT promoter is necessary for hTERT expression in human oral cancer cells

Q37090677

An unbiased in vivo screen reveals multiple transcription factors that control HPV E6-regulated hTERT in keratinocytes.

Q37208016

Stem cells of the skin and cornea: their clinical applications in regenerative medicine

Q37819938

Cultured allogenic keratinocytes for extensive burns: a retrospective study over 15 years

Q38114237

Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).

Q38316509

Suppression of α5 gene expression is closely related to the tumorigenic properties of uveal melanoma cell lines

Q38335089

E2F-1 represses transcription of the human telomerase reverse transcriptase gene

Q39095418

Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus up-regulates transcription of human telomerase reverse transcriptase promoter through interaction with transcription factor Sp1.

Q39992257

Irradiated human dermal fibroblasts are as efficient as mouse fibroblasts as a feeder layer to improve human epidermal cell culture lifespan

Q40043311

Transforming growth factor-beta inhibits telomerase through SMAD3 and E2F transcription factors

Q40078363

C-terminal p73 isoforms repress transcriptional activity of the human telomerase reverse transcriptase (hTERT) promoter

Q40360538

Sp1/Sp3-dependent regulation of human telomerase reverse transcriptase promoter activity by the bioactive sphingolipid ceramide

Q40410557

Cultured epithelial cells of cornea, conjunctiva and skin: absence of marked intrinsic divergence of their differentiated states

Q40658138

Sp1 as G1 cell cycle phase specific transcription factor in epithelial cells

Q40744465

Direct activation of TERT transcription by c-MYC.

Q40973563

Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT.

Q42046068

Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment

Q42440856

Reconstructed human cornea produced in vitro by tissue engineering

Q42474255

Deregulated expression of c-Myc depletes epidermal stem cells

Q42505079

Improvement of human keratinocyte isolation and culture using thermolysin

Q42511029

Human epithelial stem cells persist within tissue-engineered skin produced by the self-assembly approach

Q42516464

Small inhibitory RNA duplexes for Sp1 mRNA block basal and estrogen-induced gene expression and cell cycle progression in MCF-7 breast cancer cells

Q42522132

Function of AP-1 in transcription of the telomerase reverse transcriptase gene (TERT) in human and mouse cells

Q42537507

Rescue of the transcription factors Sp1 and NFI in human skin keratinocytes through a feeder-layer-dependent suppression of the proteasome activity

Q42798220

Influence of sp1/sp3 expression on corneal epithelial cells proliferation and differentiation properties in reconstructed tissues

Q42803790

The feeder layer-mediated extended lifetime of cultured human skin keratinocytes is associated with altered levels of the transcription factors Sp1 and Sp3.

Q42808773

Glutathione regulates telomerase activity in 3T3 fibroblasts

Q42828294

Differential binding of the transcription factors Sp1, AP-1, and NFI to the promoter of the human alpha5 integrin gene dictates its transcriptional activity

Q46384789

Development of an in vitro psoriatic skin model by tissue engineering

Q47353562

Constitutive overexpression of human telomerase reverse transcriptase but not c-myc blocks terminal differentiation in human HaCaT skin keratinocytes

Q47786289

Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation

Q47987665

Widely meshed autograft associated with cultured autologous epithelium for the treatment of major burns in children: report of 12 cases

Q54054967

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