High glucose-induced hypertrophy of mesangial cells is reversed by connexin43 overexpression via PTEN/Akt/mTOR signaling.

scientific article published in June 2011

High glucose-induced hypertrophy of mesangial cells is reversed by connexin43 overexpression via PTEN/Akt/mTOR signaling. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NDT/GFR265
P698PubMed publication ID21633095

P2093author name stringYang Lv
Lin Liu
Bo Fu
Zhe Feng
Xiao Hu
Li Zhuo
Guang-Yan Cai
Xiang-Mei Chen
Jian-Jun Gao
Shao-Yuan Cui
P2860cites workCardiac regulation by phosphoinositide 3-kinases and PTENQ24317248
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Mesangial cell hypertrophy by high glucose is mediated by downregulation of the tumor suppressor PTENQ28566493
Endoplasmic reticulum stress and unfolded protein response in renal pathophysiology: Janus facesQ30039723
Gap junctions regulate extracellular signal-regulated kinase signaling to affect gene transcriptionQ33564239
Molecular mechanisms of diabetic renal hypertrophyQ33702711
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Diabetic nephropathy: diagnosis, prevention, and treatmentQ34379284
Phosphoinositide 3-kinase controls early and late events in mammalian cell divisionQ34410971
Ten years of protein kinase B signalling: a hard Akt to followQ34432885
Gap junctions and the connexin protein familyQ35749952
Extracellular ATP is a pro-angiogenic factor for pulmonary artery vasa vasorum endothelial cellsQ36784736
Pathophysiological roles of gap junction in glomerular mesangial cellsQ36876316
The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implicationsQ37160617
Connexin43 phosphorylation: structural changes and biological effectsQ37421795
Nucleic acids electrotransfer-based gene therapy (electrogenetherapy): past, current, and futureQ37534480
Ecdysteroids elicit a rapid Ca2+ flux leading to Akt activation and increased protein synthesis in skeletal muscle cellsQ39719269
Coordination of mesangial cell contraction by gap junction--mediated intercellular Ca(2+) waveQ44077367
Gas6 induces Akt/mTOR-mediated mesangial hypertrophy in diabetic nephropathyQ46598128
Role of the Akt/FoxO3a pathway in TGF-beta1-mediated mesangial cell dysfunction: a novel mechanism related to diabetic kidney disease.Q47586979
PDGF regulates gap junction communication and connexin43 phosphorylation by PI 3-kinase in mesangial cells.Q52539076
Downregulation of connexin 43 expression by high glucose induces senescence in glomerular mesangial cells.Q53624401
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectmesangial cellQ3331086
overexpressionQ61643320
P304page(s)90-100
P577publication date2011-06-01
P1433published inNephrology Dialysis TransplantationQ15710302
P1476titleHigh glucose-induced hypertrophy of mesangial cells is reversed by connexin43 overexpression via PTEN/Akt/mTOR signaling.
P478volume27