Slug/SNAI2 regulates cell proliferation and invasiveness of metastatic prostate cancer cell lines.

scientific article published on 27 May 2010

Slug/SNAI2 regulates cell proliferation and invasiveness of metastatic prostate cancer cell lines. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S13277-010-0037-5
P698PubMed publication ID20506051

P50authorModjtaba Emadi-BaygiQ53801546
Frank EssmannQ98664968
Wolfgang A. SchulzQ38326200
Zahra-Soheila SoheiliQ40211284
P2093author name stringRainer Engers
Wolfgang Goering
Abdolkhaleg Deezagi
P2860cites workApaf-1 and caspase-9 deficiency prevents apoptosis in a Bax-controlled pathway and promotes clonogenic survival during paclitaxel treatmentQ80673261
Human Slug is a repressor that localizes to sites of active transcriptionQ22254334
The SLUG zinc-finger protein represses E-cadherin in breast cancerQ24292674
Negative regulation of the expressions of cytokeratins 8 and 19 by SLUG repressor protein in human breast cellsQ24296997
The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transitionQ24309569
Slug regulates integrin expression and cell proliferation in human epidermal keratinocytesQ24337235
A biomarker that identifies senescent human cells in culture and in aging skin in vivoQ24562644
The epithelial-mesenchymal transition: new insights in signaling, development, and diseaseQ24683758
Cell migration: integrating signals from front to backQ27860670
Mobilization and activation of a signaling competent alpha6beta4integrin underlies its contribution to carcinoma progressionQ28279627
Characterization of the promoter for the mouse alpha 3 integrin geneQ31109283
Functional cooperation between the microtubule and actin cytoskeletonsQ33840293
Transitions between epithelial and mesenchymal states in development and diseaseQ34761972
The Snail genes as inducers of cell movement and survival: implications in development and cancer.Q36177031
The role of epithelial-mesenchymal transition in cancer pathologyQ36845018
Role of the epithelial-mesenchymal transition regulator Slug in primary human cancersQ37410395
Downregulation of several fibulin genes in prostate cancerQ40069262
Epithelial-to-mesenchymal transition confers resistance to apoptosis in three murine mammary epithelial cell linesQ40270512
SLUG in cancer development.Q40453569
The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressorsQ40680001
Comprehensive genotypic analysis of human prostate cancer cell lines and sublines derived from metastases after orthotopic implantation in nude miceQ40702877
Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expressionQ40781214
Colon cancer cells adhesion and spreading on autocrine laminin-10 is mediated by multiple integrin receptors and modulated by EGF receptor stimulationQ40838295
Identification of the human alpha6 integrin gene promoterQ41095809
Cloning and characterization of the human beta4-integrin gene promoter and enhancersQ42464762
Transcriptomal profiling of the cellular response to DNA damage mediated by Slug (Snai2).Q42950189
SLUG (SNAI2) overexpression in embryonic development.Q52017170
Knocking-down the expression of nucleostemin significantly decreases rate of proliferation of rat bone marrow stromal stem cells in an apparently p53-independent manner.Q53503784
Short interfering RNA directed against the SLUG gene increases cell death induction in human melanoma cell lines exposed to cisplatin and fotemustine.Q53539302
Microarray analysis demonstrates a role for Slug in epidermal homeostasis.Q53540190
P433issue4
P921main subjectprostate cancerQ181257
neoplastic invasivenessQ112498967
P304page(s)297-307
P577publication date2010-05-27
P1433published inTumor BiologyQ15757842
P1476titleSlug/SNAI2 regulates cell proliferation and invasiveness of metastatic prostate cancer cell lines
P478volume31

Reverse relations

cites work (P2860)
Q367981003D Porous Chitosan-Alginate Scaffolds as an In Vitro Model for Evaluating Nanoparticle-Mediated Tumor Targeting and Gene Delivery to Prostate Cancer
Q39033598A ROS/STAT3/HIF-1α signaling cascade mediates EGF-induced TWIST1 expression and prostate cancer cell invasion
Q26799171A new role for the PI3K/Akt signaling pathway in the epithelial-mesenchymal transition
Q38178555AR function in promoting metastatic prostate cancer
Q36756685An in vitro-in vivo model of epithelial mesenchymal transition in triple negative breast cancer
Q38750022Androgens induce a distinct response of epithelial-mesenchymal transition factors in human prostate cancer cells
Q39152560BRCA1 and p53 regulate critical prostate cancer pathways.
Q33732391Differential effects of RUNX2 on the androgen receptor in prostate cancer: synergistic stimulation of a gene set exemplified by SNAI2 and subsequent invasiveness.
Q38561949E-cadherin plasticity in prostate cancer stem cell invasion
Q89454417EMT, stemness and tumor plasticity in aggressive variant neuroendocrine prostate cancers
Q30724105Epithelial mesenchymal-like transition occurs in a subset of cells in castration resistant prostate cancer bone metastases
Q86564130GATA6 is overexpressed in breast cancer and promotes breast cancer cell epithelial-mesenchymal transition by upregulating slug expression
Q93005191Histological hallmarks and role of Slug/PIP axis in pulmonary hypertension secondary to pulmonary fibrosis
Q48103088ITGB1-dependent upregulation of Caveolin-1 switches TGFβ signalling from tumour-suppressive to oncogenic in prostate cancer
Q32944410Induction of Slug by Chronic Exposure to Single-Walled Carbon Nanotubes Promotes Tumor Formation and Metastasis
Q49193255Jazf1 promotes prostate cancer progression by activating JNK/Slug
Q38771232Long non-coding RNA ATB promotes growth and epithelial-mesenchymal transition and predicts poor prognosis in human prostate carcinoma
Q39027362MTDH/AEG-1 contributes to central features of the neoplastic phenotype in bladder cancer.
Q35082366Mechanisms and functional consequences of PDEF protein expression loss during prostate cancer progression.
Q37697134Microenvironmental networks promote tumor heterogeneity and enrich for metastatic cancer stem-like cells in Luminal-A breast tumor cells.
Q38785807Novel roles for class II Phosphoinositide 3-Kinase C2β in signalling pathways involved in prostate cancer cell invasion.
Q40185493Plumbagin Inhibits Prostate Carcinogenesis in Intact and Castrated PTEN Knockout Mice via Targeting PKCε, Stat3, and Epithelial-to-Mesenchymal Transition Markers
Q37402928Progression of luminal breast tumors is promoted by ménage à trois between the inflammatory cytokine TNFα and the hormonal and growth-supporting arms of the tumor microenvironment
Q34506485SFRP2 and slug contribute to cellular resistance to apoptosis in hypertrophic scars
Q36303130SLUG is a direct transcriptional repressor of PTEN tumor suppressor
Q33639728SLUG transcription factor: a pro-survival and prognostic factor in gastrointestinal stromal tumour
Q26865846SLUG: Critical regulator of epithelial cell identity in breast development and cancer
Q39608991SNAI1 is involved in the proliferation and migration of glioblastoma cells
Q64987264SNAI2 3'untranslated region promotes the invasion of ovarian cancer cells by inducing MARCKS expression.
Q85690339Serum C-reactive protein acted as a prognostic biomarker for overall survival in metastatic prostate cancer patients
Q39012289Slug is temporally regulated by cyclin E in cell cycle and controls genome stability.
Q101237339Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis
Q39626323TMPRSS4 induces invasion and proliferation of prostate cancer cells through induction of Slug and cyclin D1.
Q34185839Targeted inactivation of Snail family EMT regulatory factors by a Co(III)-Ebox conjugate
Q47701436Targeting Gas6/TAM in cancer cells and tumor microenvironment
Q36309425The HSP90 inhibitor 17-PAG effectively inhibits the proliferation and migration of androgen-independent prostate cancer cells
Q55108871The PCAT3/PCAT9-miR-203-SNAI2 axis functions as a key mediator for prostate tumor growth and progression.
Q34505037The role of epithelial plasticity in prostate cancer dissemination and treatment resistance
Q64244654USP5 promotes epithelial-mesenchymal transition by stabilizing SLUG in hepatocellular carcinoma
Q94526757microRNA Expression Profiling in Young Prostate Cancer Patients

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