Transitions between epithelial and mesenchymal states in development and disease

scientific article

Transitions between epithelial and mesenchymal states in development and disease is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.SEMCDB.2008.02.001
P698PubMed publication ID18343170

P50authorBuzz BaumQ30505213
P2093author name stringJeffrey Settleman
Margaret P Quinlan
P2860cites workEmbryonic stem cell lines derived from human blastocystsQ27861010
Wnt proteins are lipid-modified and can act as stem cell growth factorsQ29615009
P433issue3
P921main subjectdelaminationQ22294460
P304page(s)294-308
P577publication date2008-02-09
P1433published inSeminars in Cell & Developmental BiologyQ14330411
P1476titleTransitions between epithelial and mesenchymal states in development and disease
P478volume19

Reverse relations

cites work (P2860)
Q38992057A cadherin switch underlies malignancy in high-grade gliomas.
Q90390155A potential Rho GEF and Rac GAP for coupled Rac and Rho cycles during mesenchymal-to-epithelial-like transitions
Q37334258A quest for initiating cells of head and neck cancer and their treatment
Q47303095Activated HGF-c-Met Axis in Head and Neck Cancer
Q42801184Adherens junction treadmilling during collective migration.
Q33799224AlphaE-catenin regulates actin dynamics independently of cadherin-mediated cell-cell adhesion
Q33474847Alteration of gene expression signatures of cortical differentiation and wound response in lethal clear cell renal cell carcinomas
Q37676762Altered expression of fibroblast growth factor receptor 2 isoform IIIc: relevance to endometrioid adenocarcinoma carcinogenesis and histological differentiation
Q26852158Anoikis molecular pathways and its role in cancer progression
Q89737185BIRC7 promotes epithelial-mesenchymal transition and metastasis in papillary thyroid carcinoma through restraining autophagy
Q36204798Biologic characteristics of premalignant breast disease
Q81556375Breaking down EMT
Q36658798Bridging the Gap: From 2D Cell Culture to 3D Microengineered Extracellular Matrices
Q37368971Cancer attractors: a systems view of tumors from a gene network dynamics and developmental perspective
Q47130831Cancer cell-soluble factors reprogram mesenchymal stromal cells to slow cycling, chemoresistant cells with a more stem-like state.
Q42006656Cancer stem cell markers in head and neck squamous cell carcinoma.
Q34250491Cellular and molecular processes leading to embryo formation in sponges: evidences for high conservation of processes throughout animal evolution.
Q35643796Changes in glomerular parietal epithelial cells in mouse kidneys with advanced age
Q28085565Choices for Induction of Pluripotency: Recent Developments in Human Induced Pluripotent Stem Cell Reprogramming Strategies
Q33678275Chronic inflammation and cytokines in the tumor microenvironment
Q26741429Circulating Tumor Cells in the Adenocarcinoma of the Esophagus
Q36105474Cisplatin resistance: a cellular self-defense mechanism resulting from multiple epigenetic and genetic changes
Q35486869Clinical implication of CD166 expression in salivary gland tumor.
Q38073630Collective cell migration of epithelial and mesenchymal cells
Q35032720Comprehensive proteome quantification reveals NgBR as a new regulator for epithelial-mesenchymal transition of breast tumor cells
Q41831928Computational modeling of single-cell migration: the leading role of extracellular matrix fibers
Q39031238Critical role of miR-10b in transforming growth factor-β1-induced epithelial-mesenchymal transition in breast cancer
Q38025331Current state of the development of mesenchymal stem cells into clinically applicable Schwann cell transplants
Q28506916Deficiency in Crumbs homolog 2 (Crb2) affects gastrulation and results in embryonic lethality in mice
Q97094004Development and validation of a novel immune-related prognostic model in lung squamous cell carcinoma
Q37737205Differential MicroRNA Expression Between Gastric Cancer Tissue and Non-cancerous Gastric Mucosa According to Helicobacter pylori Status
Q42407375Diversity in the molecular and cellular strategies of epithelium-to-mesenchyme transitions: Insights from the neural crest.
Q35853987Downregulation of long noncoding RNA MALAT1 induces epithelial-to-mesenchymal transition via the PI3K-AKT pathway in breast cancer.
Q37151282Downregulation of the long noncoding RNA GAS5-AS1 contributes to tumor metastasis in non-small cell lung cancer
Q50528588Driving Cancer Tumorigenesis and Metastasis Through UPR Signaling.
Q42134280Dynamic analysis of the mesenchymal-epithelial transition of blood-brain barrier forming glia in Drosophila
Q37855367Dynamics of adherens junctions in epithelial establishment, maintenance, and remodeling
Q29040399Early Regression of the Dental Lamina Underlies the Development of Diphyodont Dentitions
Q37360395Emodin ameliorates bleomycin-induced pulmonary fibrosis in rats by suppressing epithelial-mesenchymal transition and fibroblast activation
Q50188901Emodin inhibits colon cancer cell invasion and migration by suppressing epithelialmesenchymal transition via the Wnt/β-catenin pathway.
Q26830155Endocardial and epicardial epithelial to mesenchymal transitions in heart development and disease
Q37507462Enhanced FGFR signalling predisposes pancreatic cancer to the effect of a potent FGFR inhibitor in preclinical models
Q35951834Enhanced expression of fibroblast growth factor receptor 2 IIIc promotes human pancreatic cancer cell proliferation
Q39090188Epithelial splicing regulatory protein 1 is a favorable prognostic factor in pancreatic cancer that attenuates pancreatic metastases
Q38044317Epithelial to mesenchymal transition as a portal to stem cell characters embedded in gene networks.
Q57283456Epithelial-mesenchymal transition and cancer stem cells: at the crossroads of differentiation and dedifferentiation
Q37620379Epithelial-mesenchymal transition in development and cancer
Q37164129Epithelial-mesenchymal transition: a cancer researcher's conceptual friend and foe.
Q57395176Epithelial–mesenchymal transition of epicardial mesothelium is a source of cardiac CD117-positive stem cells in adult human heart
Q50592669Evaluation of aldehyde dehydrogenase 1 and transcription factors in both primary breast cancer and axillary lymph node metastases as a prognostic factor.
Q33815175Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma
Q21135539Evidence for mesenchymal-epithelial transition associated with mouse hepatic stem cell differentiation
Q41947542Evidence for partial epithelial-to-mesenchymal transition (pEMT) and recruitment of motile blastoderm edge cells during avian epiboly
Q37481495Examination of Epithelial Mesenchymal Transition in Keloid Tissues and Possibility of Keloid Therapy Target
Q37726627Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer
Q91893044Fluid shear stress coupled with narrow constrictions induce cell type-dependent morphological and molecular changes in SK-BR-3 and MDA-MB-231 cells
Q38460765Generation of cardiac progenitor cells through epicardial to mesenchymal transition.
Q38103747Genetic and non-genetic instability in tumor progression: link between the fitness landscape and the epigenetic landscape of cancer cells
Q26742115Glycosylation in Cancer: Interplay between Multidrug Resistance and Epithelial-to-Mesenchymal Transition?
Q40045355Hedgehog signaling in biliary fibrosis
Q37811158Hedgehog signaling in the liver
Q42430169High tumor-associated macrophages infiltration is associated with poor prognosis and may contribute to the phenomenon of epithelial-mesenchymal transition in gastric cancer
Q35841951Human epicardium: ultrastructural ancestry of mesothelium and mesenchymal cells
Q33872063Imaging cell shape change in living Drosophila embryos
Q53558609Immunoexpression of tenascin as a predictor of the malignancy potential of oral leukoplakia associated with a tobacco habit.
Q39421834Immunolocalization of endocan during the endothelial-mesenchymal transition process
Q28475341In Vitro Transformation of Primary Human CD34+ Cells by AML Fusion Oncogenes: Early Gene Expression Profiling Reveals Possible Drug Target in AML
Q37118924Inhibition of Akt activity induces the mesenchymal-to-epithelial reverting transition with restoring E-cadherin expression in KB and KOSCC-25B oral squamous cell carcinoma cells
Q38737715Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma.
Q38756929Is there any role of epithelial to mesenchymal transition in the pathogenesis of contrast nephropathy?
Q38204716Isoforms of receptors of fibroblast growth factors
Q39429617Isolation and characterization of stem-like cells from a human ovarian cancer cell line
Q36974720Kaposi's sarcoma-associated herpesvirus disrupts adherens junctions and increases endothelial permeability by inducing degradation of VE-cadherin
Q41836547Lamellipodia-based migrations of larval epithelial cells are required for normal closure of the adult epidermis of Drosophila
Q36179588LincRNA-ROR induces epithelial-to-mesenchymal transition and contributes to breast cancer tumorigenesis and metastasis
Q36228782Lithium Attenuates TGF-β(1)-Induced Fibroblasts to Myofibroblasts Transition in Bronchial Fibroblasts Derived from Asthmatic Patients
Q33405240Liver cancer-derived hepatitis C virus core proteins shift TGF-beta responses from tumor suppression to epithelial-mesenchymal transition
Q51772947Long Non-coding RNA HOXA11 Antisense Promotes Cell Proliferation and Invasion and Predicts Patient Prognosis in Serous Ovarian Cancer.
Q90317219Long non-coding RNA linc00645 promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-205-3p-ZEB1 axis in glioma
Q37565430MT2-MMP induces proteolysis and leads to EMT in carcinomas
Q21562167Matrix Rigidity Regulates Cancer Cell Growth and Cellular Phenotype
Q33804105Mechanisms of the epithelial-mesenchymal transition by TGF-beta
Q92840367Membranous staining of β-catenin and E-cadherin expression in patients with gastric cancer
Q34504623Methylation of the candidate biomarker TCF21 is very frequent across a spectrum of early-stage nonsmall cell lung cancers
Q46236135MicroRNA-23a promotes pancreatic cancer metastasis by targeting epithelial splicing regulator protein 1.
Q91756456MicroRNA-410-3p upregulation suppresses proliferation, invasion and migration, and promotes apoptosis in rhabdomyosarcoma cells
Q37941371MicroRNA-mediated breast cancer metastasis: from primary site to distant organs
Q37672322Molecular bases of cell-cell junctions stability and dynamics
Q38207092Molecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte.
Q49383041Molecular signature of nitric oxide on major cancer hallmarks of colorectal carcinoma
Q34895558Morphogenetic cell movements: diversity from modular mechanical properties
Q38834297Moscatilin inhibits epithelial-to-mesenchymal transition and sensitizes anoikis in human lung cancer H460 cells
Q30422568Mouse primitive streak forms in situ by initiation of epithelial to mesenchymal transition without migration of a cell population
Q42580444Myosin II promotes the anisotropic loss of the apical domain during Drosophila neuroblast ingression
Q92084207N3ICD with the transmembrane domain can effectively inhibit EMT by correcting the position of tight/adherens junctions
Q48167275Neural crest emigration: From start to stop
Q36675419New spin on an old transition: epithelial parallels in neuronal adhesion control
Q43263377Nitric oxide suppresses transforming growth factor-beta1-induced epithelial-to-mesenchymal transition and apoptosis in mouse hepatocytes
Q40617717Notochord morphogenesis in mice: Current understanding & open questions.
Q35177151Nuclear factor I-C regulates E-cadherin via control of KLF4 in breast cancer
Q38355587On the move: endocytic trafficking in cell migration.
Q30485285Oncogenic Ras-transformed human fibroblasts exhibit differential changes in contraction and migration in 3D collagen matrices
Q46347453Osteoblast migration in vertebrate bone
Q38785793Overexpression of Livin promotes migration and invasion of colorectal cancer cells by induction of epithelial-mesenchymal transition via NF-κB activation
Q90404451Oxygen Tension and the VHL-Hif1α Pathway Determine Onset of Neuronal Polarization and Cerebellar Germinal Zone Exit
Q39816900P-cadherin induces an epithelial-like phenotype in oral squamous cell carcinoma by GSK-3beta-mediated Snail phosphorylation.
Q34778528PARP-1 regulates metastatic melanoma through modulation of vimentin-induced malignant transformation.
Q54411257Phenotypic Plasticity of the Ovarian Surface Epithelium: TGF-β1 Induction of Epithelial to Mesenchymal Transition (EMT) in Vitro
Q38570239Phorbol ester phorbol-12-myristate-13-acetate induces epithelial to mesenchymal transition in human prostate cancer ARCaPE cells
Q35145928Polarity transitions during neurogenesis and germinal zone exit in the developing central nervous system
Q37996455Premetastatic niche: ready for new therapeutic interventions?
Q48506818Primer and interview: epithelial to mesenchymal transition. [Interview by Julie Kiefer].
Q36591911Prognostic impact of EMT (epithelial-mesenchymal-transition)-related protein expression in endometrial cancer
Q37194065Progress in stem cell-derived technologies for hepatocellular carcinoma
Q54193729Protein expression and promoter methylation of the candidate biomarker TCF21 in gastric cancer.
Q86490397Protein expression and promoter methylation of the candidate biomarker TCF21 in head and neck squamous cell carcinoma
Q33757116ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-kB-dependent activation of Snail
Q39856973Ral overactivation in malignant peripheral nerve sheath tumors
Q37462315Reactive oxygen species and tumor metastasis
Q37342290Remodeling epithelial cell organization: transitions between front-rear and apical-basal polarity
Q26771696Reversible Human TGF-β Signal Shifting between Tumor Suppression and Fibro-Carcinogenesis: Implications of Smad Phospho-Isoforms for Hepatic Epithelial-Mesenchymal Transitions
Q34643236Role of SIRT1 in regulation of epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasis
Q36677690Role of microRNAs in breast cancer
Q54120638S100A6 promotes the proliferation and migration of cervical cancer cells via the PI3K/Akt signaling pathway.
Q34149920SIRT1 induces EMT by cooperating with EMT transcription factors and enhances prostate cancer cell migration and metastasis.
Q26853644Salinomycin: a novel anti-cancer agent with known anti-coccidial activities
Q50527091Schwann-like cells differentiated from human dental pulp stem cells combined with a pulsed electromagnetic field can improve peripheral nerve regeneration.
Q37495453Self-organizing tissue-engineered constructs in collagen hydrogels
Q50480011Sequential introduction of reprogramming factors reveals a time-sensitive requirement for individual factors and a sequential EMT-MET mechanism for optimal reprogramming.
Q42200111Serine threonine receptor-associated protein (STRAP) plays a role in the maintenance of mesenchymal morphology
Q53321706Slug/SNAI2 regulates cell proliferation and invasiveness of metastatic prostate cancer cell lines.
Q38484478Smad3 regulates Rho signaling via NET1 in the transforming growth factor-beta-induced epithelial-mesenchymal transition of human retinal pigment epithelial cells
Q35961794Snail-induced epithelial-to-mesenchymal transition of MCF-7 breast cancer cells: systems analysis of molecular changes and their effect on radiation and drug sensitivity
Q47160414Snail1 is positively correlated with atrial fibrosis in patients with atrial fibrillation and rheumatic heart disease
Q36430004Strategies to target molecules that control the acquisition of a mesenchymal-like phenotype by carcinoma cells
Q38604585Suppression of CIP4/Par6 attenuates TGF-β1-induced epithelial-mesenchymal transition in NRK-52E cells
Q38288773Suppression of the grainyhead transcription factor 2 gene (GRHL2) inhibits the proliferation, migration, invasion and mediates cell cycle arrest of ovarian cancer cells.
Q35985845TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells
Q37062041TGF-β1 regulates cell fate during epithelial-mesenchymal transition by upregulating survivin
Q38720774TRIM37 promotes epithelial‑mesenchymal transition in colorectal cancer
Q37728859TWISTing an embryonic transcription factor into an oncoprotein
Q36263617Targeted Inhibition of Snail Activity in Breast Cancer Cells by Using a Co(III) -Ebox Conjugate.
Q47701436Targeting Gas6/TAM in cancer cells and tumor microenvironment
Q54112424Telocinobufagin inhibits the epithelial-mesenchymal transition of breast cancer cells through the phosphoinositide 3-kinase/protein kinase B/extracellular signal-regulated kinase/Snail signaling pathway.
Q34756114Tenascin C induces epithelial-mesenchymal transition-like change accompanied by SRC activation and focal adhesion kinase phosphorylation in human breast cancer cells
Q34024731The EMT (epithelial-mesenchymal-transition)-related protein expression indicates the metastatic status and prognosis in patients with ovarian cancer
Q52841593The adaptor protein Cindr regulates JNK activity to maintain epithelial sheet integrity.
Q53219888The attenuation of epithelial to mesenchymal transition and induction of anoikis by gigantol in human lung cancer H460 cells.
Q38633203The epithelial-mesenchymal transition in cancer: a potential critical topic for translational proteomic research.
Q37401193The epithelial-to-mesenchymal transition and cancer stem cells: a coalition against cancer therapies
Q37855124The extracellular matrix dimension of skeletal muscle development
Q37323439The impact of transgenic IGF-IR overexpression on mammary development and tumorigenesis
Q27320853The mechanics of metastasis: insights from a computational model
Q38255668The network of epithelial-mesenchymal transition: potential new targets for tumor resistance
Q30487545The neural crest epithelial-mesenchymal transition in 4D: a 'tail' of multiple non-obligatory cellular mechanisms
Q36849660The potential for liquid biopsies in the precision medical treatment of breast cancer
Q42342102The propensity for epithelial-mesenchymal transitions is dictated by chromatin states in the cancer cell of origin
Q38021684The rejuvenated scenario of epithelial-mesenchymal transition (EMT) and cancer metastasis
Q52861555The role of hERG1 ion channels in epithelial-mesenchymal transition and the capacity of riluzole to reduce cisplatin resistance in colorectal cancer cells.
Q37734309The role of the bone marrow derived mesenchymal stem cells in colonic epithelial regeneration.
Q55332460The transcription factor ZEB1 promotes an aggressive phenotype in prostate cancer cell lines.
Q39414383Thymosin β 4 in colorectal cancer is localized predominantly at the invasion front in tumor cells undergoing epithelial mesenchymal transition
Q37505385Trafficking and cell migration
Q42361826Transcriptional inhibition in Schwann cell development and nerve regeneration
Q38763516Transcriptome profiling reveals novel gene expression signatures and regulating transcription factors of TGFβ-induced epithelial-to-mesenchymal transition
Q28237197Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
Q28566030Tuberin regulates E-cadherin localization: implications in epithelial-mesenchymal transition
Q47140201Tumorigenesis as a process of gradual loss of original cell identity and gain of properties of neural precursor/progenitor cells.
Q33613560Tumour-initiating capacity is independent of epithelial-mesenchymal transition status in breast cancer cell lines
Q55109401Ultrastructural description of development and cell composition of primmorphs in the endemic Baikal sponge Lubomirskia baicalensis
Q30496088Unique precursors for the mesenchymal cells involved in injury response and fibrosis
Q34324979Unmasking epithelial-mesenchymal transition in a breast cancer primary culture: a study report
Q90584259Vesicle trafficking pathways that direct cell migration in 3D matrices and in vivo
Q48107131WHO 1973 grade 3 and infiltrative growth pattern proved, aberrant E-cadherin expression tends to be of predictive value for progression in a series of stage T1 high-grade bladder cancer after organ-sparing approach.
Q41603090Wnt/PCP signaling controls intracellular position of MTOCs during gastrulation convergence and extension movements
Q51136044Zeb2: Inhibiting the inhibitors in Schwann cells.
Q21091183miR-200 enhances mouse breast cancer cell colonization to form distant metastases
Q38896392miR-200 promotes the mesenchymal to epithelial transition by suppressing multiple members of the Zeb2 and Snail1 transcriptional repressor complexes.
Q45907906miR-675 mediates downregulation of Twist1 and Rb in AFP-secreting hepatocellular carcinoma.
Q37860250β-catenin as a potential key target for tumor suppression