review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1007/S10911-008-9097-1 |
P8608 | Fatcat ID | release_bpbrbp4ea5gfljtun7nzu7bwzu |
P698 | PubMed publication ID | 19002570 |
P2093 | author name string | Robert A Jones | |
Roger A Moorehead | |||
P2860 | cites work | Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2 | Q24672372 |
The protective role of pregnancy in breast cancer | Q24810274 | ||
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The transcriptional repressor Snail promotes mammary tumor recurrence | Q28272823 | ||
Oncogenic transformation by the signaling adaptor proteins insulin receptor substrate (IRS)-1 and IRS-2 | Q28294068 | ||
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r) | Q29619910 | ||
Expression of the insulin-like growth factor I receptor and urokinase plasminogen activator in breast cancer is associated with poor survival: potential for intervention with 17-allylamino geldanamycin | Q31036521 | ||
Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer | Q33890758 | ||
A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology | Q34116752 | ||
Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice | Q34342812 | ||
P190-B Rho GTPase-activating protein overexpression disrupts ductal morphogenesis and induces hyperplastic lesions in the developing mammary gland | Q34493249 | ||
Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene | Q34560337 | ||
Transitions between epithelial and mesenchymal states in development and disease | Q34761972 | ||
Type I insulin-like growth factor receptor over-expression induces proliferation and anti-apoptotic signaling in a three-dimensional culture model of breast epithelial cells | Q35012773 | ||
Isoform-specific ras activation and oncogene dependence during MYC- and Wnt-induced mammary tumorigenesis | Q35131418 | ||
Insulin-like growth factors and breast cancer | Q35170250 | ||
The insulin-like growth factor system in advanced breast cancer | Q35612304 | ||
Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II) | Q36081417 | ||
Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition | Q36320600 | ||
Paracrine overexpression of insulin-like growth factor-1 enhances mammary tumorigenesis in vivo | Q36855753 | ||
Epithelial--mesenchymal and mesenchymal--epithelial transitions in carcinoma progression. | Q36902961 | ||
Involution of the lactating mammary gland is inhibited by the IGF system in a transgenic mouse model | Q37354895 | ||
ErbB2 is required for ductal morphogenesis of the mammary gland | Q37704948 | ||
Targeted expression of des(1-3) human insulin-like growth factor I in transgenic mice influences mammary gland development and IGF-binding protein expression | Q38287546 | ||
Reversibility and recurrence of IGF-IR-induced mammary tumors | Q39859193 | ||
Characterization of a novel primary mammary tumor cell line reveals that cyclin D1 is regulated by the type I insulin-like growth factor receptor. | Q39978258 | ||
Elevated insulin-like growth factor-I receptor (IGF-IR) levels in primary breast tumors associated with BRCA1 mutations | Q40086113 | ||
Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor | Q40427703 | ||
Type I insulin-like growth factor receptor function in breast cancer. | Q41727242 | ||
Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an epithelial-to-mesenchymal transition mediated by NF-kappaB and snail | Q42738098 | ||
The IGF-I receptor in mitogenesis and transformation of mouse embryo cells: role of receptor number | Q42804213 | ||
IGF-II induces rapid beta-catenin relocation to the nucleus during epithelium to mesenchyme transition | Q42826102 | ||
Targeted disruption of the IGF-I receptor gene decreases cellular proliferation in mammary terminal end buds | Q43770402 | ||
Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis | Q44259982 | ||
Breast cancer incidence among atomic bomb survivors, Hiroshima and Nagasaki, 1950-69 | Q44274260 | ||
Expression of ovine insulin-like growth factor-1 (IGF-1) stimulates alveolar bud development in mammary glands of transgenic mice | Q45113758 | ||
Ductal growth is impeded in mammary glands of C-neu transgenic mice. | Q46014880 | ||
Elevated insulin-like growth factor I receptor autophosphorylation and kinase activity in human breast cancer. | Q46268677 | ||
Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis. | Q53334281 | ||
Protective effects of pregnancy and lactation against N-methyl-N-nitrosourea-induced mammary carcinomas in female Lewis rats. | Q53424173 | ||
Increased Milk Yield in Transgenic Mice Expressing Insulin-like Growth Factor 1 | Q58294101 | ||
Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes | Q70641455 | ||
Insulin-like growth factor-I and insulin-like growth factor binding protein-3 inhibit involution of the mammary gland following lactation: studies in transgenic mice | Q71559313 | ||
Cooperative interaction between mutant p53 and des(1-3)IGF-I accelerates mammary tumorigenesis | Q73510884 | ||
Inability of overexpressed des(1-3)human insulin-like growth factor I (IGF-I) to inhibit forced mammary gland involution is associated with decreased expression of IGF signaling molecules | Q73620060 | ||
Inhibition of mammary epithelial apoptosis and sustained phosphorylation of Akt/PKB in MMTV-IGF-II transgenic mice | Q73786615 | ||
Metastasizing mammary carcinomas in H19 enhancers-Igf2 transgenic mice | Q74508495 | ||
Transgenic hypersecretion of des(1-3) human insulin-like growth factor I in mouse milk has limited effects on the gastrointestinal tract in suckling pups | Q77897047 | ||
Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation | Q80213822 | ||
Overexpression of des(1-3) insulin-like growth factor 1 in the mammary glands of transgenic mice delays the loss of milk production with prolonged lactation | Q81002699 | ||
Lack of sustained regression of c-MYC-induced mammary adenocarcinomas following brief or prolonged MYC inactivation | Q81165932 | ||
Expression of insulin-like growth factor-I receptor, estrogen receptor alpha, Bcl-2 and Bax proteins in human breast cancer | Q81828284 | ||
P433 | issue | 4 | |
P921 | main subject | overexpression | Q61643320 |
P304 | page(s) | 407-413 | |
P577 | publication date | 2008-11-11 | |
P1433 | published in | Journal of Mammary Gland Biology and Neoplasia | Q15724460 |
P1476 | title | The impact of transgenic IGF-IR overexpression on mammary development and tumorigenesis | |
P478 | volume | 13 |
Q34515619 | Association between insulin-like growth factor-1 receptor (IGF1R) negativity and poor prognosis in a cohort of women with primary breast cancer |
Q45093278 | Clinical pathological characteristics and prognostic analysis of 1,013 breast cancer patients with diabetes |
Q50766711 | Clinical pathological characteristics and prognostic analysis of diabetic women with luminal subtype breast cancer. |
Q26860821 | Crosstalk of the Insulin-Like Growth Factor Receptor with the Wnt Signaling Pathway in Breast Cancer |
Q34133760 | ErbB2 enhances mammary tumorigenesis, oncogene-independent recurrence and metastasis in a model of IGF-IR-mediated mammary tumorigenesis |
Q47143930 | Expression of insulin-like growth factor-1 receptor in circulating tumor cells of patients with breast cancer is associated with patient outcomes. |
Q36251216 | Fetal alcohol exposure increases mammary tumor susceptibility and alters tumor phenotype in rats |
Q34333651 | Golgi calcium pump secretory pathway calcium ATPase 1 (SPCA1) is a key regulator of insulin-like growth factor receptor (IGF1R) processing in the basal-like breast cancer cell line MDA-MB-231 |
Q33916778 | IGF-I during primiparous pregnancy and maternal risk of breast cancer |
Q34564798 | Inactivation of RARβ inhibits Wnt1-induced mammary tumorigenesis by suppressing epithelial-mesenchymal transitions. |
Q90570117 | Insulin-like growth factor-1 receptor (IGF-1R) expression on circulating tumor cells (CTCs) and metastatic breast cancer outcome: results from the TransMYME trial |
Q46014808 | Insulin-like growth factor-1 receptor gene expression is associated with survival in breast cancer: a comprehensive analysis of gene copy number, mRNA and protein expression. |
Q38868797 | Low-fidelity alternative DNA repair carcinogenesis theory may interpret many cancer features and anticancer strategies |
Q38221690 | Low-fidelity compensatory backup alternative DNA repair pathways may unify current carcinogenesis theories |
Q36047389 | Osteopontin regulates proliferation, apoptosis, and migration of murine claudin-low mammary tumor cells |
Q33707003 | Prolactin enhances insulin-like growth factor I receptor phosphorylation by decreasing its association with the tyrosine phosphatase SHP-2 in MCF-7 breast cancer cells |
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