Kaposi's sarcoma-associated herpesvirus disrupts adherens junctions and increases endothelial permeability by inducing degradation of VE-cadherin

scientific article published on 24 September 2008

Kaposi's sarcoma-associated herpesvirus disrupts adherens junctions and increases endothelial permeability by inducing degradation of VE-cadherin is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.01042-08
P8608Fatcat IDrelease_inpynzdkcjbqxnhuzqowni77yy
P932PMC publication ID2583667
P698PubMed publication ID18815301
P5875ResearchGate publication ID23278693

P50authorShou-Jiang GaoQ41839530
P2093author name stringWhitney Greene
Fengchun Ye
Li-Wu Qian
P2860cites workVascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartmentsQ24299236
Integrin alphaVbeta3 Binds to the RGD motif of glycoprotein B of Kaposi's sarcoma-associated herpesvirus and functions as an RGD-dependent entry receptorQ24301712
Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, beta-catenin, and the phosphatase DEP-1/CD148Q24303092
Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptorQ24322090
Kaposi's sarcoma-associated herpesvirus induction of AP-1 and interleukin 6 during primary infection mediated by multiple mitogen-activated protein kinase pathwaysQ24534690
Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5Q24658142
Murine Model for Dengue Virus-Induced Lethal Disease with Increased Vascular PermeabilityQ27477548
Dengue-virus-infected dendritic cells trigger vascular leakage through metalloproteinase overproductionQ27477724
VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherinQ28116308
Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesisQ28140788
VE-cadherin: adhesion at arm's lengthQ28255695
KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcomaQ28284765
Detection of herpesvirus-like DNA sequences in Kaposi's sarcoma in patients with and without HIV infectionQ28299060
Integrins regulate VE-cadherin and catenins: dependence of this regulation on Src, but not on Ras.Q30477010
Vascular endothelial-cadherin tyrosine phosphorylation in angiogenic and quiescent adult tissuesQ33556970
Molecular biology of KSHV in relation to AIDS-associated oncogenesisQ33560572
Early and sustained expression of latent and host modulating genes in coordinated transcriptional program of KSHV productive primary infection of human primary endothelial cellsQ33623056
Spindle cell conversion by Kaposi's sarcoma-associated herpesvirus: formation of colonies and plaques with mixed lytic and latent gene expression in infected primary dermal microvascular endothelial cell culturesQ33841987
Paclitaxel is safe and effective in the treatment of advanced AIDS-related Kaposi's sarcomaQ33880209
Activation of matrix-metalloproteinase-2 and membrane-type-1-matrix-metalloproteinase in endothelial cells and induction of vascular permeability in vivo by human immunodeficiency virus-1 Tat protein and basic fibroblast growth factorQ33948194
VEGF receptor 2 and the adherens junction as a mechanical transducer in vascular endothelial cellsQ34035717
p120-Catenin regulates clathrin-dependent endocytosis of VE-cadherinQ34099519
Respiratory syncytial virus stimulation of vascular endothelial cell growth Factor/Vascular permeability factorQ40844640
Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcomaQ40972068
Local increase of beta 1-integrin expression in cocultures of immortalized hepatocytes and sinusoidal endothelial cellsQ41440591
The prognostic significance of facial lymphoedema in HIV-seropositive subjects with Kaposi sarcomaQ42096173
Polarized distribution of integrin and fibronectin in retinal pigment epitheliumQ42517016
ERK1/2 and MEK1/2 induced by Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) early during infection of target cells are essential for expression of viral genes and for establishment of infectionQ42931199
Focal adhesion kinase is critical for entry of Kaposi's sarcoma-associated herpesvirus into target cellsQ43181946
Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling.Q44074366
Breakdown of paraendothelial barrier function during Marburg virus infection is associated with early tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1.Q44121333
HIV-1 Tat-mediated apoptosis in human brain microvascular endothelial cellsQ44320785
Virus-induced Abl and Fyn kinase signals permit coxsackievirus entry through epithelial tight junctionsQ45420840
Elevated virus loads of Kaposi's sarcoma-associated human herpesvirus 8 predict Kaposi's sarcoma disease progression, but elevated levels of human immunodeficiency virus type 1 do not.Q45731974
Relationship of human herpesvirus 8 peripheral blood virus load and Kaposi's sarcoma clinical stageQ45739908
Induction of chemokine production by latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells.Q45976216
Tyrosine phosphorylation of VE-cadherin prevents binding of p120- and beta-catenin and maintains the cellular mesenchymal stateQ46096039
Cytotrophoblasts infected with a pathogenic human cytomegalovirus strain dysregulate cell-matrix and cell-cell adhesion molecules: a quantitative analysisQ46220802
Transformation of primary human endothelial cells by Kaposi's sarcoma-associated herpesvirusQ47675996
Src kinase phosphorylates vascular endothelial-cadherin in response to vascular endothelial growth factor: identification of tyrosine 685 as the unique target site.Q51804915
Regulation of E-cadherin/Catenin association by tyrosine phosphorylation.Q52537297
VE-cadherin simultaneously stimulates and inhibits cell proliferation by altering cytoskeletal structure and tension.Q52551401
Productive infection of HUVEC by HHV-8 is associated with changes compatible with angiogenic transformations.Q54636945
Detection and quantification of Kaposi's sarcoma-associated herpesvirus to predict AIDS-associated Kaposi's sarcomaQ73734599
Interendothelial junctions and their role in the control of angiogenesis, vascular permeability and leukocyte transmigrationQ74314946
Pathogenic and nonpathogenic hantaviruses differentially regulate endothelial cell responsesQ34161805
Seroconversion to antibodies against Kaposi's sarcoma-associated herpesvirus-related latent nuclear antigens before the development of Kaposi's sarcomaQ34383343
Kaposi's sarcoma-associated herpesvirus fusion-entry receptor: cystine transporter xCT.Q34507156
Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma.Q34548882
Immune reconstitution inflammatory syndrome associated with Kaposi's sarcomaQ34559661
Modulation of Kaposi's sarcoma-associated herpesvirus infection and replication by MEK/ERK, JNK, and p38 multiple mitogen-activated protein kinase pathways during primary infectionQ34648384
Transitions between epithelial and mesenchymal states in development and diseaseQ34761972
Molecular genetics of Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) epidemiology and pathogenesisQ35026060
Kaposi's sarcoma-associated herpesvirus infection of blood endothelial cells induces lymphatic differentiationQ35137826
Human cytomegalovirus (HCMV) infection of endothelial cells promotes naive monocyte extravasation and transfer of productive virus to enhance hematogenous dissemination of HCMVQ35140023
Kaposi's sarcoma-associated herpesvirus promotes angiogenesis by inducing angiopoietin-2 expression via AP-1 and Ets1Q35785255
Kaposi's sarcoma-associated herpesvirus infection promotes invasion of primary human umbilical vein endothelial cells by inducing matrix metalloproteinasesQ35914351
Linking Rap to cell adhesionQ36076035
Endothelial cadherins and tumor angiogenesis.Q36300450
Signaling mechanisms regulating endothelial permeabilityQ36350076
Endothelial cell infection and hemostasisQ36550148
Hantaviruses direct endothelial cell permeability by sensitizing cells to the vascular permeability factor VEGF, while angiopoietin 1 and sphingosine 1-phosphate inhibit hantavirus-directed permeabilityQ36673210
Epithelial-mesenchymal transition and tumour invasionQ36934031
Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesisQ36981844
Dual regulation of endothelial junctional permeabilityQ37000246
VE-cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formationQ37046356
Organization of multiprotein complexes at cell-cell junctionsQ37118549
Cell surface heparan sulfate is a receptor for human herpesvirus 8 and interacts with envelope glycoprotein K8.1.Q38295126
Kaposi's sarcoma-associated herpesvirus induces the phosphatidylinositol 3-kinase-PKC-zeta-MEK-ERK signaling pathway in target cells early during infection: implications for infectivityQ38359214
The catalytic activity of the Src family kinases is required to disrupt cadherin-dependent cell-cell contactsQ38477296
Human blood-brain barrier disruption by retroviral-infected lymphocytes: role of myosin light chain kinase in endothelial tight-junction disorganizationQ38861783
RhoA-GTPase facilitates entry of Kaposi's sarcoma-associated herpesvirus into adherent target cells in a Src-dependent mannerQ39321282
Efficient infection by a recombinant Kaposi's sarcoma-associated herpesvirus cloned in a bacterial artificial chromosome: application for genetic analysisQ39683622
Human herpesvirus 8 envelope glycoprotein B mediates cell adhesion via its RGD sequenceQ39733480
Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) infection of human fibroblast cells occurs through endocytosisQ39776421
Productive lytic replication of a recombinant Kaposi's sarcoma-associated herpesvirus in efficient primary infection of primary human endothelial cellsQ39996542
Human herpesvirus 8 infects and replicates in primary cultures of activated B lymphocytes through DC-SIGN.Q40002946
Kaposi's sarcoma-associated herpesvirus induces sustained levels of vascular endothelial growth factors A and C early during in vitro infection of human microvascular dermal endothelial cells: biological implicationsQ40040603
Big endothelin-1 and interleukin-6 modulation in human microvascular endothelial cells after human herpesvirus 8 infectionQ40272431
DC-SIGN is a receptor for human herpesvirus 8 on dendritic cells and macrophagesQ40327365
Bluetongue virus and double-stranded RNA increase human vascular permeability: role of p38 MAPK.Q40476287
In vitro assessment of human endothelial cell permeability: effects of inflammatory cytokines and dengue virus infectionQ40525374
Identification of the Ebola virus glycoprotein as the main viral determinant of vascular cell cytotoxicity and injuryQ40616926
Mechanisms of VE-cadherin processing and degradation in microvascular endothelial cells.Q40665549
Integrin alpha3beta1 (CD 49c/29) is a cellular receptor for Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) entry into the target cellsQ40749885
Human herpesvirus 8 envelope-associated glycoprotein B interacts with heparan sulfate-like moietiesQ40802330
P433issue23
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
P304page(s)11902-11912
P577publication date2008-09-24
P1433published inJournal of VirologyQ1251128
P1476titleKaposi's sarcoma-associated herpesvirus disrupts adherens junctions and increases endothelial permeability by inducing degradation of VE-cadherin
P478volume82

Reverse relations

cites work (P2860)
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