KSHV-Mediated Regulation of Par3 and SNAIL Contributes to B-Cell Proliferation

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KSHV-Mediated Regulation of Par3 and SNAIL Contributes to B-Cell Proliferation is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1005801
P932PMC publication ID4963126
P698PubMed publication ID27463802

P50authorZhiguo SunQ82415198
Erle S RobertsonQ88590600
Darine W El-NaccacheQ50094874
P2093author name stringHem C Jha
Rajnish K Singh
Santosh K Upadhyay
Sushil K Sahu
P2860cites workStabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasionQ24321517
The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)Q24534460
Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progressionQ24633875
Epithelial cell polarity: a major gatekeeper against cancer?Q24635870
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2Q24646996
Central role of Snail1 in the regulation of EMT and resistance in cancer: a target for therapeutic interventionQ26864839
The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphomaQ27852536
Epithelial-mesenchymal transitions in development and diseaseQ27860630
The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cellsQ28143877
Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by SnailQ28187811
Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcomaQ28242984
Primary effusion lymphomaQ28303700
A novel snail-related transcription factor Smuc regulates basic helix-loop-helix transcription factor activities via specific E-box motifsQ28507154
Matrix metalloproteinases: regulators of the tumor microenvironmentQ29619858
Kaposi's sarcoma-associated herpesvirus genome programming during the early stages of primary infection of peripheral blood mononuclear cells.Q30369871
Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasisQ30416351
The PAR proteins: fundamental players in animal cell polarizationQ30434403
EC5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and p53 tumor suppressorsQ33261811
Matrix metalloproteinase 9 expression is induced by Epstein-Barr virus latent membrane protein 1 C-terminal activation regions 1 and 2.Q33815241
A human herpesvirus microRNA inhibits p21 expression and attenuates p21-mediated cell cycle arrestQ33826818
Epstein-Barr virus nuclear antigen 3C facilitates G1-S transition by stabilizing and enhancing the function of cyclin D1.Q33828576
The epidemiologic, pathologic, and clinical features of AIDS-associated pulmonary Kaposi's sarcomaQ33892577
Expression of transcription factors snail, slug, and twist in human bladder carcinomaQ34142066
Epimorphin promotes human hepatocellular carcinoma invasion and metastasis through activation of focal adhesion kinase/extracellular signal-regulated kinase/matrix metalloproteinase-9 axisQ82299271
The manipulation of miRNA-gene regulatory networks by KSHV induces endothelial cell motilityQ84470156
A protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere shortening.Q34179693
Kaposi's Sarcoma Herpesvirus Upregulates Aurora A Expression to Promote p53 Phosphorylation and UbiquitylationQ34186981
Overexpression of Snail is associated with lymph node metastasis and poor prognosis in patients with gastric cancerQ34476703
Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma.Q34548882
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complexQ34550834
CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progressionQ34627193
Molecular and cellular mechanisms of KSHV oncogenesis of Kaposi's sarcoma associated with HIV/AIDSQ34663095
Update on Kaposi's sarcoma and other HHV8 associated diseases. Part 2: pathogenesis, Castleman's disease, and pleural effusion lymphomaQ34764819
Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of SnailQ34972866
Small molecule growth inhibitors of human oncogenic gammaherpesvirus infected B-cellsQ35007967
Mechanisms of Kaposi's Sarcoma-Associated Herpesvirus Latency and ReactivationQ35010647
The Single RBP-Jκ Site within the LANA Promoter Is Crucial for Establishing Kaposi's Sarcoma-Associated Herpesvirus Latency during Primary InfectionQ35077558
Molecular Biology of Kaposi's Sarcoma-associated Herpesvirus and Related OncogenesisQ35124404
Chromatinization of the KSHV Genome During the KSHV Life CycleQ35237492
Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosisQ35746891
PATJ, a tight junction-associated PDZ protein, is a novel degradation target of high-risk human papillomavirus E6 and the alternatively spliced isoform 18 E6Q35785387
O-GlcNAc signalling: implications for cancer cell biologyQ35793071
Kaposi's sarcoma-associated herpesvirus infection promotes invasion of primary human umbilical vein endothelial cells by inducing matrix metalloproteinasesQ35914351
Coordinated protein sorting, targeting and distribution in polarized cellsQ36015653
Bub1 in Complex with LANA Recruits PCNA To Regulate Kaposi's Sarcoma-Associated Herpesvirus Latent Replication and DNA Translesion SynthesisQ36086302
The Kaposi's sarcoma-associated herpesvirus LANA protein stabilizes and activates c-MycQ36099076
DNA viruses in human cancer: an integrated overview on fundamental mechanisms of viral carcinogenesis.Q36524782
Endothelial cell infection and hemostasisQ36550148
Endothelial cell- and lymphocyte-based in vitro systems for understanding KSHV biology.Q36647098
H2AX phosphorylation is important for LANA-mediated Kaposi's sarcoma-associated herpesvirus episome persistenceQ36760020
Kaposi's sarcoma-associated herpesvirus disrupts adherens junctions and increases endothelial permeability by inducing degradation of VE-cadherinQ36974720
Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and functionQ37021785
The M type K15 protein of Kaposi's sarcoma-associated herpesvirus regulates microRNA expression via its SH2-binding motif to induce cell migration and invasionQ37033356
Genetic disruption of KSHV major latent nuclear antigen LANA enhances viral lytic transcriptional programQ37060535
Biomarkers for epithelial-mesenchymal transitionsQ37209254
Disruption of E-cadherin by matrix metalloproteinase directly mediates epithelial-mesenchymal transition downstream of transforming growth factor-beta1 in renal tubular epithelial cells.Q37278443
The epithelial polarity program: machineries involved and their hijacking by cancer.Q37333603
Phosphoinositide 3-kinases in cell migrationQ37340915
Remodeling epithelial cell organization: transitions between front-rear and apical-basal polarityQ37342290
NF-kappaB signaling modulation by EBV and KSHV.Q37745983
Dynamics of adherens junctions in epithelial establishment, maintenance, and remodelingQ37855367
The role of endothelial–mesenchymal transition in development and pathological processQ38021441
Kaposi's sarcoma-associated herpesvirus-encoded LANA contributes to viral latent replication by activating phosphorylation of survivinQ38859450
EBNA3C regulates p53 through induction of Aurora kinase B.Q38908573
Expression of Snail and Slug in renal cell carcinoma: E-cadherin repressor Snail is associated with cancer invasion and prognosisQ39496646
Expression of snail in upper urinary tract urothelial carcinoma: prognostic significance and implications for tumor invasionQ39643976
Bub1 and CENP-F can contribute to Kaposi's sarcoma-associated herpesvirus genome persistence by targeting LANA to kinetochoresQ39675686
Snail is critical for tumor growth and metastasis of ovarian carcinomaQ39792925
Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus (KSHV) upregulates survivin expression in KSHV-Associated B-lymphoma cells and contributes to their proliferationQ39852047
Repression of PTEN phosphatase by Snail1 transcriptional factor during gamma radiation-induced apoptosisQ40028787
NF-kappaB is essential for the progression of KSHV- and EBV-infected lymphomas in vivoQ40335673
Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen induces chromosomal instability through inhibition of p53 functionQ40335991
Snail regulates p21(WAF/CIP1) expression in cooperation with E2A and TwistQ40489885
Kaposi's sarcoma-associated herpesvirus-encoded LANA can induce chromosomal instability through targeted degradation of the mitotic checkpoint kinase Bub1Q40607781
ECM and Cell Surface Proteolysis: Regulating Cellular EcologyQ41656253
EBNA3C-mediated regulation of aurora kinase B contributes to Epstein-Barr virus-induced B-cell proliferation through modulation of the activities of the retinoblastoma protein and apoptotic caspasesQ42273501
Kaposi's sarcoma: an opportunistic infection by human herpesvirus-8 in ulcerative colitisQ42788636
Transport of galectin-3 between the nucleus and cytoplasm. II. Identification of the signal for nuclear exportQ42805175
Role of p53 and NF-kappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cellsQ44534508
Biological roles and prognostic values of the epithelial–mesenchymal transition‐mediating transcription factors Twist, ZEB1 and Slug in diffuse large B‐cell lymphomaQ45241456
Primary effusion lymphoma: a distinct clinicopathologic entity associated with the Kaposi's sarcoma-associated herpes virus.Q45769785
Induction of chemokine production by latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells.Q45976216
PAR-6 is a conserved PDZ domain-containing protein that colocalizes with PAR-3 in Caenorhabditis elegans embryos.Q47068779
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)e1005801
P577publication date2016-07-27
P1433published inPLOS PathogensQ283209
P1476titleKSHV-Mediated Regulation of Par3 and SNAIL Contributes to B-Cell Proliferation
P478volume12

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cites work (P2860)
Q40056844Cellular responses to human cytomegalovirus infection: Induction of a mesenchymal-to-epithelial transition (MET) phenotype
Q93170230Diversified Application of Barcoded PLATO (PLATO-BC) Platform for Identification of Protein Interactions
Q52565524Epigenetic Regulation of Tumor Suppressors by Helicobacter pylori Enhances EBV-Induced Proliferation of Gastric Epithelial Cells
Q93074235KSHV-encoded LANA protects the cellular replication machinery from hypoxia induced degradation
Q90319823Molecular Biology of KSHV in Relation to HIV/AIDS-Associated Oncogenesis
Q59349302Upsetting the Balance: When Viruses Manipulate Cell Polarity Control

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