EBNA3C regulates p53 through induction of Aurora kinase B.

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EBNA3C regulates p53 through induction of Aurora kinase B. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.3310
P932PMC publication ID4467402
P698PubMed publication ID25691063

P50authorDarine W El-NaccacheQ50094874
Zhiguo SunQ82415198
Erle S RobertsonQ88590600
P2093author name stringHem C Jha
Karren Yang
P2860cites workThe amino-terminal domains of Epstein-Barr virus nuclear proteins 3A, 3B, and 3C interact with RBPJ(kappa)Q24310605
Solution structure of the ETS domain from murine Ets-1: a winged helix-turn-helix DNA binding motifQ24563315
Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosisQ24682520
p53, the cellular gatekeeper for growth and divisionQ27860990
Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochoresQ28201606
p53 mutations in human cancersQ28302973
Significance of Aurora B overexpression in hepatocellular carcinoma. Aurora B Overexpression in HCC.Q30988387
Epstein-barr virus latency in B cells leads to epigenetic repression and CpG methylation of the tumour suppressor gene BimQ33474807
Epstein-Barr virus nuclear antigen 3C facilitates G1-S transition by stabilizing and enhancing the function of cyclin D1.Q33828576
Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting propertyQ33836931
Epstein-Barr virus EBNA3C can disrupt multiple cell cycle checkpoints and induce nuclear division divorced from cytokinesis.Q33891861
Upregulation of Cellular Bcl-2 by the KSHV Encoded RTA Promotes Virion ProductionQ34013770
Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinaseQ34068377
Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.Q45345467
p53 Deficiency leads to compensatory up-regulation of p16INK4aQ46110603
AZD1152, a novel and selective aurora B kinase inhibitor, induces growth arrest, apoptosis, and sensitization for tubulin depolymerizing agent or topoisomerase II inhibitor in human acute leukemia cells in vitro and in vivoQ80313902
Epstein-Barr virus nuclear antigen 3C stabilizes Gemin3 to block p53-mediated apoptosisQ34102722
Kaposi's Sarcoma Herpesvirus Upregulates Aurora A Expression to Promote p53 Phosphorylation and UbiquitylationQ34186981
E2F1 mediated apoptosis induced by the DNA damage response is blocked by EBV nuclear antigen 3C in lymphoblastoid cells.Q34205875
p53 protein at the hub of cellular DNA damage response pathways through sequence-specific and non-sequence-specific DNA bindingQ34263254
Epstein-Barr virus and cancerQ34297027
Epstein-Barr virus infection and human malignanciesQ34328170
The metastatic suppressor Nm23-H1 interacts with EBNA3C at sequences located between the glutamine- and proline-rich domains and can cooperate in activation of transcriptionQ34362138
Aurora kinases: new targets for cancer therapyQ34587271
An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cellsQ34626894
The EBV Latent Antigen 3C Inhibits Apoptosis through Targeted Regulation of Interferon Regulatory Factors 4 and 8.Q34711793
Epstein-Barr virus nuclear antigen 3C recruits histone deacetylase activity and associates with the corepressors mSin3A and NCoR in human B-cell linesQ34782258
Epstein-Barr virus nuclear antigen 3C targets p53 and modulates its transcriptional and apoptotic activitiesQ34872837
Epstein-Barr virus nuclear protein EBNA3C is required for cell cycle progression and growth maintenance of lymphoblastoid cellsQ35540042
The ubiquitin-proteasomal system is critical for multiple myeloma: implications in drug discoveryQ35824929
Aurora B controls kinetochore-microtubule attachments by inhibiting Ska complex-KMN network interactionQ35839779
Aurora-kinase inhibitors as anticancer agentsQ35968406
Aurora B kinase phosphorylates and instigates degradation of p53Q36066322
H2AX phosphorylation is important for LANA-mediated Kaposi's sarcoma-associated herpesvirus episome persistenceQ36760020
Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23Q36806063
Epstein-Barr virus nuclear protein EBNA3C residues critical for maintaining lymphoblastoid cell growthQ37132783
Deregulated Aurora-B induced tetraploidy promotes tumorigenesisQ37280830
Mutations in the p53 Tumor Suppressor Gene: Important Milestones at the Various Steps of TumorigenesisQ37903701
Epstein-Barr virus essential antigen EBNA3C attenuates H2AX expressionQ38854742
Epstein-Barr virus nuclear antigen 3C interacts with histone deacetylase to repress transcriptionQ39594681
Three Epstein-Barr virus latency proteins independently promote genomic instability by inducing DNA damage, inhibiting DNA repair and inactivating cell cycle checkpointsQ39806215
Epstein-Barr virus nuclear antigen 3C is a transcriptional regulatorQ39870334
Epstein-Barr virus nuclear antigen 3C augments Mdm2-mediated p53 ubiquitination and degradation by deubiquitinating Mdm2.Q39879529
MDM2-dependent inhibition of p53 is required for Epstein-Barr virus B-cell growth transformation and infected-cell survivalQ39895212
EBNA3C can modulate the activities of the transcription factor Necdin in association with metastasis suppressor protein Nm23-H1.Q39900063
EWS-Fli1 up-regulates expression of the Aurora A and Aurora B kinases.Q39906143
The selective Aurora B kinase inhibitor AZD1152 is a potential new treatment for multiple myeloma.Q40036249
AZD1152, a selective inhibitor of Aurora B kinase, inhibits human tumor xenograft growth by inducing apoptosisQ40118416
Epstein-barr virus-induced resistance to drugs that activate the mitotic spindle assembly checkpoint in Burkitt's lymphoma cellsQ40221184
Conserved cell cycle regulatory properties within the amino terminal domain of the Epstein-Barr virus nuclear antigen 3C.Q40338623
Protein acetylation regulates both PU.1 transactivation and Ig kappa 3' enhancer activityQ40364683
The transcriptional repressor hDaxx potentiates p53-dependent apoptosisQ40520539
Epstein-Barr virus nuclear antigen 3C regulates cyclin A/p27 complexes and enhances cyclin A-dependent kinase activityQ40594951
Precipitation of the Epstein-Barr virus protein EBNA 2 by an EBNA 3c-specific monoclonal antibodyQ41479044
EBNA3C-mediated regulation of aurora kinase B contributes to Epstein-Barr virus-induced B-cell proliferation through modulation of the activities of the retinoblastoma protein and apoptotic caspasesQ42273501
Expression of Epstein-Barr virus transformation-associated genes in tissues of patients with EBV lymphoproliferative diseaseQ43936463
P4510describes a project that usesImageQuantQ112270642
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)5788-5803
P577publication date2015-03-01
P1433published inOncotargetQ1573155
P1476titleEBNA3C regulates p53 through induction of Aurora kinase B.
P478volume6

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cites work (P2860)
Q46011991A post-translational modification switch controls coactivator function of histone methyltransferases G9a and GLP.
Q57025486An EBNA3C-deleted Epstein-Barr virus (EBV) mutant causes B-cell lymphomas with delayed onset in a cord blood-humanized mouse model
Q61450799EBNA3C facilitates RASSF1A downregulation through ubiquitin-mediated degradation and promoter hypermethylation to drive B-cell proliferation
Q47117102EBV and Apoptosis: The Viral Master Regulator of Cell Fate?
Q59352774Epstein-Barr Virus MicroRNA miR-BART5-3p Inhibits p53 Expression
Q28074586Epstein-Barr Virus: Diseases Linked to Infection and Transformation
Q95728086Frequency of Epstein–Barr Virus DNA in Formalin-Fixed Paraffin-Embedded Tissue of Patients with Ductal Breast Carcinoma
Q37295271Inhibiting cell migration and cell invasion by silencing the transcription factor ETS-1 in human bladder cancer
Q36087231KSHV-Mediated Regulation of Par3 and SNAIL Contributes to B-Cell Proliferation
Q39281253Multiple viral infections in primary effusion lymphoma: a model of viral cooperation in lymphomagenesis.
Q90282529RNA Sequencing Analyses of Gene Expression during Epstein-Barr Virus Infection of Primary B Lymphocytes
Q26752541Role of EBNA-3 Family Proteins in EBV Associated B-cell Lymphomagenesis
Q26767186The Role of Gammaherpesviruses in Cancer Pathogenesis
Q90798983The activity of Aurora kinase B is required for dengue virus release
Q54978478Transcriptional and epigenetic modulation of autophagy promotes EBV oncoprotein EBNA3C induced B-cell survival.

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