The transcriptional repressor hDaxx potentiates p53-dependent apoptosis

scientific article published on 31 August 2004

The transcriptional repressor hDaxx potentiates p53-dependent apoptosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M310801200
P698PubMed publication ID15339933

P2093author name stringFiamma Mantovani
Giannino Del Sal
Licio Collavin
Monica Gostissa
Claudio Brancolini
Silvano Piazza
Claudio Schneider
Elisa Guida
Manuela Morelli
P2860cites workSequestration and inhibition of Daxx-mediated transcriptional repression by PMLQ22253162
Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosisQ22253228
EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genesQ22253257
PML regulates p53 acetylation and premature senescence induced by oncogenic RasQ22254666
FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activationQ24290412
Regulation of p53 activity in nuclear bodies by a specific PML isoformQ24290520
TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activationQ24291517
Modification of Daxx by small ubiquitin-related modifier-1.Q40714117
The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrestQ40834838
Fas ligand-induced c-Jun kinase activation in lymphoid cells requires extensive receptor aggregation but is independent of DAXX, and Fas-mediated cell death does not involve DAXX, RIP, or RAIDD.Q40867405
Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs).Q40920307
The Pax3-FKHR oncoprotein is unresponsive to the Pax3-associated repressor hDaxxQ40944377
Different impact of p53 and p21 on the radiation response of mouse tissuesQ42798283
Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21Q59054204
p63 and p73 are required for p53-dependent apoptosis in response to DNA damageQ59065672
Apoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasmQ24291544
ASPP proteins specifically stimulate the apoptotic function of p53Q24291844
The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cellsQ24292183
Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activityQ24292712
Essential role of the 58-kDa microspherule protein in the modulation of Daxx-dependent transcriptional repression as revealed by nucleolar sequestrationQ24294193
Daxx Silencing Sensitizes Cells to Multiple Apoptotic PathwaysQ24296344
Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein DaxxQ24315012
ZIP kinase triggers apoptosis from nuclear PML oncogenic domainsQ24315479
Daxx, a Novel Fas-Binding Protein That Activates JNK and ApoptosisQ24316216
Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse developmentQ24600961
PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1Q24670576
Surfing the p53 networkQ28032484
Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1.Q28117154
The function of PML in p53-dependent apoptosisQ28140732
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2Q28210189
The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insultsQ28210433
PML is a direct p53 target that modulates p53 effector functionsQ28586691
Live or let die: the cell's response to p53Q29547663
Pondering the promyelocytic leukemia protein (PML) puzzle: possible functions for PML nuclear bodiesQ33337386
Kinetics of p53 binding to promoter sites in vivoQ33558659
Cellular proteins localized at and interacting within ND10/PML nuclear bodies/PODs suggest functions of a nuclear depotQ34101415
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.Q34108288
The Daxx enigmaQ34166615
Neuronal life and death: an essential role for the p53 familyQ34201997
Inhibition of stress-inducible kinase pathways by tumorigenic mutant p53.Q34462553
p73: Friend or foe in tumorigenesisQ34770297
Dissecting Fas signaling with an altered-specificity death-domain mutant: requirement of FADD binding for apoptosis but not Jun N-terminal kinase activationQ34986210
Regulation of p53 functions: let's meet at the nuclear bodies.Q35145846
Molecular mechanisms involved in CD43-mediated apoptosis of TF-1 cells. Roles of transcription Daxx expression, and adhesion moleculesQ38293363
Identification of Daxx interacting with p73, one of the p53 family, and its regulation of p53 activity by competitive interaction with PMLQ39922653
P433issue46
P407language of work or nameEnglishQ1860
P304page(s)48013-48023
P577publication date2004-08-31
P1433published inJournal of Biological ChemistryQ867727
P1476titleThe transcriptional repressor hDaxx potentiates p53-dependent apoptosis
P478volume279

Reverse relations

cites work (P2860)
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