KSHV Induction of Angiogenic and Lymphangiogenic Phenotypes

scientific article published on 30 March 2012

KSHV Induction of Angiogenic and Lymphangiogenic Phenotypes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3389/FMICB.2012.00102
P932PMC publication ID3315823
P698PubMed publication ID22479258
P5875ResearchGate publication ID223960889

P2093author name stringMichael Lagunoff
Terri A Dimaio
P2860cites workIdentification of cellular genes targeted by KSHV-encoded microRNAsQ21131610
Kaposi's sarcoma-associated herpesvirus induction of AP-1 and interleukin 6 during primary infection mediated by multiple mitogen-activated protein kinase pathwaysQ24534690
Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cellsQ24555724
Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcomaQ28242984
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formationQ28285842
Roles of matrix metalloproteinases in cancer progression and their pharmacological targetingQ28298681
Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomasQ28299069
Kaposi's sarcoma associated herpes virus (KSHV) induced COX-2: a key factor in latency, inflammation, angiogenesis, cell survival and invasionQ28472867
Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryoQ28586040
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endotheliumQ28587604
Identification of microRNAs of the herpesvirus familyQ29618671
Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's diseaseQ29619158
Surface downregulation of major histocompatibility complex class I, PE-CAM, and ICAM-1 following de novo infection of endothelial cells with Kaposi's sarcoma-associated herpesvirusQ30311122
Remodeling of endothelial adherens junctions by Kaposi's sarcoma-associated herpesvirusQ30439948
Expression of vascular endothelial growth factor receptor-3 and podoplanin suggests a lymphatic endothelial cell origin of Kaposi's sarcoma tumor cells.Q30653484
EC5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and p53 tumor suppressorsQ33261811
Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6 and G-protein-coupled receptor regulate angiopoietin-2 expression in lymphatic endothelial cells.Q33283844
Kaposin-B Enhances the PROX1 mRNA Stability during Lymphatic Reprogramming of Vascular Endothelial Cells by Kaposi's Sarcoma Herpes VirusQ33668719
Long-term infection and transformation of dermal microvascular endothelial cells by human herpesvirus 8.Q33817882
Human herpesvirus 8 (HHV-8)-encoded cytokines induce expression of and autocrine signaling by vascular endothelial growth factor (VEGF) in HHV-8-infected primary-effusion lymphoma cell lines and mediate VEGF-independent antiapoptotic effectsQ33849065
Cloning and identification of a microRNA cluster within the latency-associated region of Kaposi's sarcoma-associated herpesvirusQ33883910
The lytic transcriptome of Kaposi's sarcoma-associated herpesvirus reveals extensive transcription of noncoding regions, including regions antisense to important genes.Q34046103
Viral G protein-coupled receptor up-regulates Angiopoietin-like 4 promoting angiogenesis and vascular permeability in Kaposi's sarcomaQ34069841
Latent KSHV Infection of Endothelial Cells Induces Integrin Beta3 to Activate Angiogenic PhenotypesQ34102739
Kaposi's sarcoma-like tumors in a human herpesvirus 8 ORF74 transgenic mouseQ34471059
Lymphatic and vascular origin of Kaposi's sarcoma spindle cells during tumor development.Q34513991
Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma.Q34548882
G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activatorQ42833351
Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.Q44166149
Viral IL-6-induced cell proliferation and immune evasion of interferon activityQ44218062
Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR.Q44277985
Modulation of host gene expression by the constitutively active G protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus.Q46029178
The Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) K1 protein induces expression of angiogenic and invasion factorsQ47755368
Immortalization of primary endothelial cells by the K1 protein of Kaposi's sarcoma-associated herpesvirusQ53347753
Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma–associated herpesvirusQ56794246
Vascular Endothelial Growth Factor-C (VEGF-C) and its Receptors KDR and flt-4 are Expressed in AIDS-Associated Kaposi’s SarcomaQ57382283
PAX2 expression by HHV-8-infected endothelial cells induced a proangiogenic and proinvasive phenotypeQ58620070
Human herpesvirus 8 acute infection of endothelial cells induces monocyte chemoattractant protein 1-dependent capillary-like structure formation: role of the IKK/NF- B pathwayQ58620073
Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cellsQ71563744
Prox1 function is required for the development of the murine lymphatic systemQ73025820
Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3Q74489252
Activation of proMMP-2 and Src by HHV8 vGPCR in human pulmonary arterial endothelial cellsQ79450896
The manipulation of miRNA-gene regulatory networks by KSHV induces endothelial cell motilityQ84470156
Kaposi's sarcoma among persons with AIDS: a sexually transmitted infection?Q34996973
Kaposi sarcoma herpesvirus K5 removes CD31/PECAM from endothelial cellsQ35128724
Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphomaQ35131811
Kaposi's sarcoma-associated herpesvirus infection of blood endothelial cells induces lymphatic differentiationQ35137826
Latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells activates hypoxia-induced factorsQ35139228
Direct activation of emmprin and associated pathogenesis by an oncogenic herpesvirusQ35453802
Latent KSHV infection increases the vascular permeability of human endothelial cellsQ35553639
Expression of Tie1, Tie2, and angiopoietins 1, 2, and 4 in Kaposi's sarcoma and cutaneous angiosarcomaQ35745558
Vascular endothelial growth factor and basic fibroblast growth factor present in Kaposi's sarcoma (KS) are induced by inflammatory cytokines and synergize to promote vascular permeability and KS lesion developmentQ35765203
Kaposi's sarcoma-associated herpesvirus promotes angiogenesis by inducing angiopoietin-2 expression via AP-1 and Ets1Q35785255
Human Herpesvirus-8-Transformed Endothelial Cells Have Functionally Activated Vascular Endothelial Growth Factor/Vascular Endothelial Growth Factor ReceptorQ35788580
Kaposi's sarcoma-associated herpesvirus infection promotes invasion of primary human umbilical vein endothelial cells by inducing matrix metalloproteinasesQ35914351
The KSHV viral IL-6 homolog is sufficient to induce blood to lymphatic endothelial cell differentiation.Q36433542
KSHV activation of VEGF secretion and invasion for endothelial cells is mediated through viral upregulation of emmprin‐induced signal transductionQ36457808
Activation of Akt through gp130 receptor signaling is required for Kaposi's sarcoma-associated herpesvirus-induced lymphatic reprogramming of endothelial cellsQ36845797
Kaposi's sarcoma-associated herpesvirus disrupts adherens junctions and increases endothelial permeability by inducing degradation of VE-cadherinQ36974720
VEGF in biological control.Q36989723
Kaposi's sarcoma-associated herpesvirus-G protein-coupled receptor-expressing endothelial cells exhibit reduced migration and stimulated chemotaxis by chemokine inverse agonistsQ37196331
Positive and negative modulation of angiogenesis by VEGFR1 ligandsQ37401612
Kaposi's sarcoma-associated herpesvirus glycoproteins B and K8.1 regulate virion egress and synthesis of vascular endothelial growth factor and viral interleukin-6 in BCBL-1 cellsQ38348410
Cancer in Kampala, Uganda, in 1989-91: changes in incidence in the era of AIDS.Q38889973
Immunostaining for CD31 and CD34 in Kaposi sarcomaQ39658331
Remodeling of VE-cadherin junctions by the human herpes virus 8 G-protein coupled receptor.Q39659259
Array-based transcript profiling and limiting-dilution reverse transcription-PCR analysis identify additional latent genes in Kaposi's sarcoma-associated herpesvirusQ39729318
KSHV-encoded miRNAs target MAF to induce endothelial cell reprogrammingQ39751014
Kaposi's sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cellsQ39877852
Monocytes in Kaposi's sarcoma lesions are productively infected by human herpesvirus 8Q39881608
Kaposi's sarcoma-associated herpesvirus upregulates angiogenin during infection of human dermal microvascular endothelial cells, which induces 45S rRNA synthesis, antiapoptosis, cell proliferation, migration, and angiogenesisQ39892759
Kaposi's sarcoma-associated herpesvirus viral IFN regulatory factor 3 stabilizes hypoxia-inducible factor-1 alpha to induce vascular endothelial growth factor expressionQ40002571
Kaposi's sarcoma-associated herpesvirus induces sustained levels of vascular endothelial growth factors A and C early during in vitro infection of human microvascular dermal endothelial cells: biological implicationsQ40040603
A potential alpha-helix motif in the amino terminus of LANA encoded by Kaposi's sarcoma-associated herpesvirus is critical for nuclear accumulation of HIF-1alpha in normoxiaQ40106826
Kaposi's sarcoma-associated herpesvirus induces sustained NF-kappaB activation during de novo infection of primary human dermal microvascular endothelial cells that is essential for viral gene expressionQ40173444
Conservation of virally encoded microRNAs in Kaposi sarcoma--associated herpesvirus in primary effusion lymphoma cell lines and in patients with Kaposi sarcoma or multicentric Castleman diseaseQ40177470
Cyclooxygenase 2 induced by Kaposi's sarcoma-associated herpesvirus early during in vitro infection of target cells plays a role in the maintenance of latent viral gene expressionQ40267788
B-Raf-dependent expression of vascular endothelial growth factor-A in Kaposi sarcoma-associated herpesvirus-infected human B cells.Q40459751
Host gene induction and transcriptional reprogramming in Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8)-infected endothelial, fibroblast, and B cells: insights into modulation events early during infectionQ40598301
Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor constitutively activates NF-kappa B and induces proinflammatory cytokine and chemokine production via a C-terminal signaling determinantQ40797202
The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor promotes endothelial cell survival through the activation of Akt/protein kinase B.Q40814685
KSHV-encoded CC chemokine vMIP-III is a CCR4 agonist, stimulates angiogenesis, and selectively chemoattracts TH2 cellsQ40901369
Angiogenic and HIV-inhibitory functions of KSHV-encoded chemokinesQ41088030
Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferationQ41133441
Kaposi's sarcoma-associated herpesvirus confers a survival advantage to endothelial cellsQ42141115
The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alphaQ42796220
Angiogenesis and hematopoiesis induced by Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6.Q42814766
P304page(s)102
P577publication date2012-03-30
P1433published inFrontiers in MicrobiologyQ27723481
P1476titleKSHV Induction of Angiogenic and Lymphangiogenic Phenotypes
P478volume3

Reverse relations

cites work (P2860)
Q36336086An APE1 inhibitor reveals critical roles of the redox function of APE1 in KSHV replication and pathogenic phenotypes
Q47552839Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis
Q57040576Endothelins in inflammatory neurological diseases
Q36911706Ets-1 is required for the activation of VEGFR3 during latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells.
Q38611188Expression and Subcellular Localization of the Kaposi's Sarcoma-Associated Herpesvirus K15P Protein during Latency and Lytic Reactivation in Primary Effusion Lymphoma Cells
Q39585656For the Future Studies of Kaposi’s Sarcoma-Associated Herpesvirus
Q38610039Herpesviruses shape tumour microenvironment through exosomal transfer of viral microRNAs
Q49363063KSHV LANA upregulates the expression of epidermal growth factor like domain 7 to promote angiogenesis.
Q93074235KSHV-encoded LANA protects the cellular replication machinery from hypoxia induced degradation
Q26750211Lymph vessels: the forgotten second circulation in health and disease
Q92238951Modulation of Angiogenic Processes by the Human Gammaherpesviruses, Epstein-Barr Virus and Kaposi's Sarcoma-Associated Herpesvirus
Q92586530STING is dispensable during KSHV infection of primary endothelial cells
Q64247511Towards Better Understanding of KSHV Life Cycle: from Transcription and Posttranscriptional Regulations to Pathogenesis

Search more.