P-cadherin induces an epithelial-like phenotype in oral squamous cell carcinoma by GSK-3beta-mediated Snail phosphorylation.

scientific article

P-cadherin induces an epithelial-like phenotype in oral squamous cell carcinoma by GSK-3beta-mediated Snail phosphorylation. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/CARCIN/BGP175
P698PubMed publication ID19654099

P50authorAnja BosserhoffQ43183440
P2093author name stringAlbert Dowejko
Karin Bauer
T E Reichert
Richard Josef Bauer
P2860cites workp38 mitogen-activated protein kinase regulates canonical Wnt-beta-catenin signaling by inactivation of GSK3betaQ39926291
Truncated P-cadherin is produced in oral squamous cell carcinoma.Q39959796
Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3.Q40641191
Calcium-dependent cell-cell adhesion molecules (cadherins): subclass specificities and possible involvement of actin bundlesQ41530185
A switch from E-cadherin to N-cadherin expression indicates epithelial to mesenchymal transition and is of strong and independent importance for the progress of prostate cancerQ42522113
Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancerQ42855720
GSK-3beta sets Snail's paceQ43429452
Plasminogen activator inhibitor-1 inhibits prostate tumor growth through endothelial apoptosis.Q53540023
Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transitionQ24305416
HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transitionQ24318681
Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly.Q24608988
GSK-3: tricks of the trade for a multi-tasking kinaseQ24624069
Snail and SIP1 increase cancer invasion by upregulating MMP family in hepatocellular carcinoma cellsQ24645625
P-cadherin expression and survival rate in oral squamous cell carcinoma: an immunohistochemical studyQ24812605
The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cellsQ28143877
The snail superfamily of zinc-finger transcription factorsQ28216843
PTEN and GSK3beta: key regulators of progression to androgen-independent prostate cancerQ28292541
ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation.Q33878896
Epithelial to mesenchymal transition during gastrulation: an embryological viewQ34014907
Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition.Q34400238
Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progressionQ34655105
Transitions between epithelial and mesenchymal states in development and diseaseQ34761972
Cadherins as Modulators of Cellular PhenotypeQ35564806
Prognostic relevance of P-cadherin expression in melanocytic skin tumours analysed by high-throughput tissue microarraysQ35770092
Matrilysin (matrix metalloproteinase-7) mediates E-cadherin ectodomain shedding in injured lung epitheliumQ35791414
The role of altered cell-cell communication in melanoma progressionQ35875599
Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cellsQ36255048
Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial-mesenchymal transitionQ36321284
The role of epithelial-mesenchymal transition in oral squamous cell carcinoma and oral submucous fibrosisQ36835159
Role of glycogen synthase kinase-3 in cell fate and epithelial-mesenchymal transitionsQ36857776
Posttranslational truncation of E-cadherin and significance for tumour progressionQ36857851
Snail up-regulates proinflammatory mediators and inhibits differentiation in oral keratinocytesQ37074083
Inhibition of Akt activity induces the mesenchymal-to-epithelial reverting transition with restoring E-cadherin expression in KB and KOSCC-25B oral squamous cell carcinoma cellsQ37118924
Increased expression of beta-catenin, phosphorylated glycogen synthase kinase 3beta, cyclin D1, and c-myc in laterally spreading colorectal tumorsQ37149354
The ectodomain shedding of E-cadherin by ADAM15 supports ErbB receptor activationQ38291507
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectphenotypeQ104053
phosphorylationQ242736
oral squamous cell carcinomaQ18553522
P304page(s)1781-1788
P577publication date2009-07-14
P1433published inCarcinogenesisQ326022
P1476titleP-cadherin induces an epithelial-like phenotype in oral squamous cell carcinoma by GSK-3beta-mediated Snail phosphorylation
P478volume30

Reverse relations

cites work (P2860)
Q92617250AAVC-I promotes apoptosis of human oral squamous cell carcinoma through the mitochondrial pathway
Q93040530Context-dependent EMT programs in cancer metastasis
Q34334509De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells
Q35624074Deregulation of Snai2 is associated with metastasis and poor prognosis in tongue squamous cell carcinoma
Q34371623Downregulation of P-cadherin expression in hepatocellular carcinoma induces tumorigenicity.
Q35783218ERK/GSK3β/Snail signaling mediates radiation-induced alveolar epithelial-to-mesenchymal transition.
Q21129333Emerging roles of glycogen synthase kinase 3 in the treatment of brain tumors
Q36652148Epithelial to mesenchymal transition in head and neck squamous cell carcinoma
Q48215330Exclusion from spheroid formation identifies loss of essential cell-cell adhesion molecules in colon cancer cells.
Q38847534Expression array analysis of the hepatocyte growth factor invasive program
Q27013811GSK-3 as potential target for therapeutic intervention in cancer
Q37764097Glycogen synthase kinase 3 beta: can it be a target for oral cancer
Q33927161HOXA9 promotes homotypic and heterotypic cell interactions that facilitate ovarian cancer dissemination via its induction of P-cadherin
Q27003394P-Cadherin Linking Breast Cancer Stem Cells and Invasion: A Promising Marker to Identify an "Intermediate/Metastable" EMT State
Q26781906P-cadherin and the journey to cancer metastasis
Q53675972P-cadherin expression in Merkel cell carcinomas is associated with prolonged recurrence-free survival.
Q39238903P-cadherin functional role is dependent on E-cadherin cellular context: a proof of concept using the breast cancer model
Q37707040P-cadherin promotes ovarian cancer dissemination through tumor cell aggregation and tumor-peritoneum interactions
Q34460713Progression of oral squamous cell carcinoma accompanied with reduced E-cadherin expression but not cadherin switch.
Q36282521Role of glycogen synthase kinase-3β and PPAR-γ on epithelial-to-mesenchymal transition in DSS-induced colorectal fibrosis
Q39565594Slit-2 facilitates interaction of P-cadherin with Robo-3 and inhibits cell migration in an oral squamous cell carcinoma cell line
Q24297953The human HECA interacts with cyclins and CDKs to antagonize Wnt-mediated proliferation and chemoresistance of head and neck cancer cells
Q38364407The role of P-cadherin in skin biology and skin pathology: lessons from the hair follicle
Q55061427[Expression and clinical significance of nuclear factor κB/B cell lymphoma-2 signal pathway and glycogen synthase kinase 3β in oral squamous cell carcinoma].

Search more.