scholarly article | Q13442814 |
P2093 | author name string | Fabio Coppedè | |
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The ubiquitin pathway in Parkinson's disease | Q48015939 | ||
Segregation of a missense mutation in the microtubule-associated protein tau gene with familial frontotemporal dementia and parkinsonism | Q48395727 | ||
Levels of alpha-synuclein mRNA in sporadic Parkinson disease patients | Q48489167 | ||
DNA methylation of Alzheimer disease and tauopathy-related genes in postmortem brain | Q48521070 | ||
SPG11 spastic paraplegia. A new cause of juvenile parkinsonism | Q48739111 | ||
Different methylation of the TNF-alpha promoter in cortex and substantia nigra: Implications for selective neuronal vulnerability | Q48875058 | ||
A two-stage meta-analysis identifies several new loci for Parkinson's disease | Q21144948 | ||
Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update | Q22252904 | ||
Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression | Q24293587 | ||
Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity | Q24301946 | ||
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism | Q24309753 | ||
Aging-associated alteration of subtelomeric methylation in Parkinson's disease. | Q53390945 | ||
Genetic variability in the SNCA gene influences α-synuclein levels in the blood and brain | Q56637599 | ||
Collaborative Analysis of α-Synuclein Gene Promoter Variability and Parkinson Disease | Q57977634 | ||
Novel mutations in SPG11 cause hereditary spastic paraplegia associated with early-onset levodopa-responsive Parkinsonism | Q59153436 | ||
MicroRNA and proteome expression profiling in early-symptomatic α-synuclein(A30P)-transgenic mice | Q82775800 | ||
HDAC6 regulates aggresome-autophagy degradation pathway of α-synuclein in response to MPP+-induced stress | Q83206996 | ||
Increased incidence of Parkinson disease among relatives of patients with Gaucher disease | Q83228051 | ||
Accumulation of histone deacetylase 6, an aggresome-related protein, is specific to Lewy bodies and glial cytoplasmic inclusions | Q83339692 | ||
MicroRNAs in Parkinson's disease | Q83371481 | ||
Identification of blood microRNAs associated to Parkinsonĭs disease | Q83372764 | ||
Study of methylation levels of parkin gene promoter in Parkinson's disease patients | Q84333501 | ||
Global DNA hypomethylation and DNA hypermethylation of the alpha synuclein promoter in females with anorexia nervosa | Q95790350 | ||
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation | Q24312713 | ||
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy | Q24317471 | ||
Hereditary early-onset Parkinson's disease caused by mutations in PINK1 | Q24337084 | ||
Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36. | Q24535854 | ||
Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease | Q24596763 | ||
Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies | Q24606055 | ||
Post-transcriptional regulation of alpha-synuclein expression by mir-7 and mir-153 | Q24633965 | ||
Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease. | Q24634577 | ||
Genome-wide association study reveals genetic risk underlying Parkinson's disease | Q24646654 | ||
Mutations in the GIGYF2 (TNRC15) gene at the PARK11 locus in familial Parkinson disease | Q24656075 | ||
Kufor-Rakeb syndrome, pallido-pyramidal degeneration with supranuclear upgaze paresis and dementia, maps to 1p36 | Q24680678 | ||
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease | Q27860459 | ||
alpha-Synuclein locus triplication causes Parkinson's disease | Q27860533 | ||
GIGYF2 is present in endosomal compartments in the mammalian brains and enhances IGF-1-induced ERK1/2 activation | Q28116164 | ||
Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase | Q28116395 | ||
The complex language of chromatin regulation during transcription | Q28131748 | ||
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology | Q28131833 | ||
Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease | Q28257086 | ||
Aggresome formation and neurodegenerative diseases: therapeutic implications | Q28265926 | ||
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease | Q28292932 | ||
FBXO7 mutations cause autosomal recessive, early-onset parkinsonian-pyramidal syndrome | Q28302099 | ||
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease | Q28307422 | ||
alpha-Synuclein produces a long-lasting increase in neurotransmitter release | Q28510893 | ||
A MicroRNA feedback circuit in midbrain dopamine neurons | Q28513149 | ||
α-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity | Q28572683 | ||
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system | Q28594502 | ||
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database | Q29417106 | ||
Repression of alpha-synuclein expression and toxicity by microRNA-7. | Q29542272 | ||
The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia | Q29547174 | ||
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease | Q29547175 | ||
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease | Q29614762 | ||
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease | Q29614900 | ||
The PINK1/Parkin pathway regulates mitochondrial morphology | Q29615641 | ||
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila | Q29617091 | ||
Genomewide association study for susceptibility genes contributing to familial Parkinson disease | Q30437480 | ||
POLG1-related and other "mitochondrial Parkinsonisms": an overview. | Q37827400 | ||
Polyglutamine diseases: the special case of ataxin-3 and Machado-Joseph disease | Q37899333 | ||
Genetic mutations and functions of PINK1. | Q37904442 | ||
Identification of gene expression changes in transgenic C. elegans overexpressing human alpha-synuclein | Q38518569 | ||
MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function | Q39545068 | ||
Protection of dopaminergic cells from MPP+-mediated toxicity by histone deacetylase inhibition | Q39676713 | ||
Allelic imbalance of expression and epigenetic regulation within the alpha-synuclein wild-type and p.Ala53Thr alleles in Parkinson disease. | Q39722408 | ||
Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair | Q39823278 | ||
Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors. | Q39955983 | ||
CpG hypermethylation of the UCHL1 gene promoter is associated with pathogenesis and poor prognosis in renal cell carcinoma | Q39979336 | ||
Lrrk2 G2385R is an ancestral risk factor for Parkinson's disease in Asia | Q40251831 | ||
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach. | Q40503405 | ||
Tau and alpha-synuclein in susceptibility to, and dementia in, Parkinson's disease | Q42628290 | ||
Clinical spectrum of Kufor-Rakeb syndrome in the Chilean kindred with ATP13A2 mutations | Q42947297 | ||
DJ-1 mutations are a rare cause of recessively inherited early onset parkinsonism mediated by loss of protein function | Q43073853 | ||
Global microRNA expression profiling of Caenorhabditis elegans Parkinson's disease models | Q43187683 | ||
Methylation status and neurodegenerative markers in Parkinson disease | Q43292322 | ||
Association between anorexia nervosa and the hsKCa3 gene: a family-based and case control study. | Q43861801 | ||
Gaucher disease with parkinsonian manifestations: does glucocerebrosidase deficiency contribute to a vulnerability to parkinsonism? | Q44479792 | ||
The parkinsonian phenotype of spinocerebellar ataxia type 3 in a Taiwanese family | Q44984888 | ||
DNA hypermethylation of the alpha synuclein promoter in patients with alcoholism | Q45239060 | ||
Valproic acid is neuroprotective in the rotenone rat model of Parkinson's disease: involvement of alpha-synuclein. | Q45922508 | ||
Nuclear localization of alpha-synuclein and its interaction with histones | Q46597702 | ||
??? | Q64786027 | ||
Association analysis of MAPT H1 haplotype and subhaplotypes in Parkinson's disease | Q30493604 | ||
Replication of MAPT and SNCA, but not PARK16-18, as susceptibility genes for Parkinson's disease. | Q30499875 | ||
Elevated alpha-synuclein mRNA levels in individual UV-laser-microdissected dopaminergic substantia nigra neurons in idiopathic Parkinson's disease | Q33323265 | ||
CpG demethylation enhances alpha-synuclein expression and affects the pathogenesis of Parkinson's disease | Q33760744 | ||
Environmental neurotoxic pesticide increases histone acetylation to promote apoptosis in dopaminergic neuronal cells: relevance to epigenetic mechanisms of neurodegeneration | Q33762517 | ||
Drosophila histone deacetylase 6 protects dopaminergic neurons against {alpha}-synuclein toxicity by promoting inclusion formation | Q33948478 | ||
One-carbon metabolism and Alzheimer's disease: focus on epigenetics | Q34094250 | ||
FGF20 rs12720208 SNP and microRNA-433 variation: no association with Parkinson's disease in Spanish patients. | Q34115520 | ||
The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility | Q34157005 | ||
Regulation of intracellular manganese homeostasis by Kufor-Rakeb syndrome-associated ATP13A2 protein | Q34197130 | ||
Parkin genetics: one model for Parkinson's disease | Q34300017 | ||
DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy | Q34399382 | ||
Abnormal methylation of the common PARK2 and PACRG promoter is associated with downregulation of gene expression in acute lymphoblastic leukemia and chronic myeloid leukemia | Q34467458 | ||
Methylation regulates alpha-synuclein expression and is decreased in Parkinson's disease patients' brains. | Q34660005 | ||
Alpha-synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseases | Q34685028 | ||
Molecular insights into Parkinson's disease | Q34988753 | ||
Protective effects of valproic acid on the nigrostriatal dopamine system in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease | Q35385117 | ||
Epigenetic mechanisms in developmental programming of adult disease. | Q35581063 | ||
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, protects dopaminergic neurons from neurotoxin-induced damage | Q35708210 | ||
Advances in epigenetics and epigenomics for neurodegenerative diseases | Q35709124 | ||
Exploring the link between glucocerebrosidase mutations and parkinsonism | Q35955350 | ||
Paraquat induces epigenetic changes by promoting histone acetylation in cell culture models of dopaminergic degeneration | Q36123405 | ||
The role of glucocerebrosidase mutations in Parkinson disease and Lewy body disorders | Q36486264 | ||
Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein | Q36718966 | ||
Genome-wide linkage analysis of a Parkinsonian-pyramidal syndrome pedigree by 500 K SNP arrays | Q36719174 | ||
Biomarkers of folate and vitamin B(12) status in cerebrospinal fluid | Q36950520 | ||
Spinocerebellar ataxia 2 (SCA2). | Q37140787 | ||
Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases | Q37332243 | ||
Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release | Q37397403 | ||
Histone deacetylases as targets for the treatment of human neurodegenerative diseases | Q37602632 | ||
Epigenetic regulation in the pathophysiology of Alzheimer's disease | Q37680418 | ||
Early-onset L-dopa-responsive parkinsonism with pyramidal signs due to ATP13A2, PLA2G6, FBXO7 and spatacsin mutations | Q37776461 | ||
Epigenetics in neurodegeneration: a new layer of complexity. | Q37782161 | ||
Genetic Analysis of Pathways to Parkinson Disease | Q37801078 | ||
P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
P6216 | copyright status | copyrighted | Q50423863 |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Parkinson's disease | Q11085 |
P304 | page(s) | 489830 | |
P577 | publication date | 2012-05-01 | |
P1433 | published in | The Scientific World Journal | Q7762585 |
P1476 | title | Genetics and epigenetics of Parkinson's disease. | |
P478 | volume | 2012 |
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Q54112963 | Acetylome in Human Fibroblasts From Parkinson's Disease Patients. |
Q39355888 | Acute exposure to a Mn/Zn ethylene-bis-dithiocarbamate fungicide leads to mitochondrial dysfunction and increased reactive oxygen species production in Caenorhabditis elegans |
Q54159456 | Alpha-synuclein A53T mutation is not frequent on a sample of Brazilian Parkinson's disease patients. |
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Q48713195 | Circulating microRNAs in Neurodegenerative Diseases. |
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