Epigenetic mechanisms in neurological and neurodegenerative diseases

scientific article published on 27 February 2015

Epigenetic mechanisms in neurological and neurodegenerative diseases is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.3389/FNCEL.2015.00058
P932PMC publication ID4343006
P698PubMed publication ID25774124
P5875ResearchGate publication ID272418285

P2093author name stringRosalinda Guevara-Guzmán
Octavio Mercado-Gómez
Jorge Landgrave-Gómez
P2860cites workA two-stage meta-analysis identifies several new loci for Parkinson's diseaseQ21144948
Long-term outcomes of children treated with the ketogenic diet in the pastQ43173500
Global microRNA expression profiling of Caenorhabditis elegans Parkinson's disease modelsQ43187683
Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processingQ44915813
Differential upregulation of extracellular matrix molecules associated with the appearance of granule cell dispersion and mossy fiber sprouting during epileptogenesis in a murine model of temporal lobe epilepsyQ45121746
Dysregulation of histone acetylation in the APP/PS1 mouse model of Alzheimer's disease.Q45922651
Physiology. When metabolism and epigenetics converge.Q45997632
Connecting threads: epigenetics and metabolismQ46493363
Nuclear localization of alpha-synuclein and its interaction with histonesQ46597702
Long-term antioxidant supplementation attenuates oxidative stress markers and cognitive deficits in senescent-accelerated OXYS rats.Q46771873
Disruption of neocortical histone H3 homeostasis by soluble Aβ: implications for Alzheimer's diseaseQ46946698
Reduction with age in methylcytosine in the promoter region -224 approximately -101 of the amyloid precursor protein gene in autopsy human cortexQ48162019
DNA methylation of Alzheimer disease and tauopathy-related genes in postmortem brainQ48521070
Cardioprotection by intermittent fasting in ratsQ48703491
S-adenosylmethionine reduces the progress of the Alzheimer-like features induced by B-vitamin deficiency in mice.Q50974734
REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis.Q52049234
Genetics and epigenetics of Parkinson's disease.Q53375184
Epilepsia. Ketogenic diet and treatments. Introduction/perspectivesQ82804304
Epigenetic mechanisms in Alzheimer's diseaseQ83829640
Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation updateQ22252904
EUKARYOTIC CYTOSINE METHYLTRANSFERASESQ22255656
Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicityQ24301946
H3.3/H2A.Z double variant-containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regionsQ24317641
Epigenetic differences arise during the lifetime of monozygotic twinsQ24531005
Cerebrospinal fluid S-adenosylmethionine in depression and dementia: effects of treatment with parenteral and oral S-adenosylmethionineQ24562104
Caloric restriction reduces age-related and all-cause mortality in rhesus monkeysQ24568041
DNA methylation and memory formationQ24596970
A decade of exploring the cancer epigenome - biological and translational implicationsQ24614467
Distinct DNA methylation changes highly correlated with chronological age in the human brainQ24616264
Epigenetic mechanisms in drug addictionQ24645709
Pathology and pathophysiology of the amygdala in epileptogenesis and epilepsyQ24650174
Epigenetic landscape of Parkinson's disease: emerging role in disease mechanisms and therapeutic modalitiesQ27023811
The language of covalent histone modificationsQ27860931
The role of chromatin during transcriptionQ27860995
REST and stress resistance in ageing and Alzheimer's diseaseQ28236857
Repressor element-1 silencing transcription factor (REST)-dependent epigenetic remodeling is critical to ischemia-induced neuronal deathQ28260806
Granule cell dispersion in the dentate gyrus of humans with temporal lobe epilepsyQ28270060
Genomic DNA methylation: the mark and its mediatorsQ28290773
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's diseaseQ28307422
Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genesQ28511419
Neuronal expression of zinc finger transcription factor REST/NRSF/XBR geneQ28579417
Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuliQ28591800
NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseasesQ28650457
Epigenetic regulation in psychiatric disordersQ29616296
Functions of site-specific histone acetylation and deacetylationQ29617894
Tau-mediated neurodegeneration in Alzheimer's disease and related disordersQ29618148
A review of the clinical evidence for complementary and alternative therapies in Parkinson's disease.Q30365907
Deep sequencing reveals increased DNA methylation in chronic rat epilepsyQ30557209
DNA methylation of BDNF as a biomarker of early-life adversityQ30653771
Molecular neuropathology of human mesial temporal lobe epilepsyQ33748790
Fasting followed by vegetarian diet in patients with rheumatoid arthritis: a systematic reviewQ33938371
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapyQ34030634
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbensQ34086476
Altered histone acetylation is associated with age-dependent memory impairment in mice.Q34114011
Phytochemicals: cancer chemoprevention and suppression of tumor onset and metastasisQ34134534
Ketone bodies as signaling metabolites.Q34252732
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitorQ34316485
The many faces of REST oversee epigenetic programming of neuronal genesQ34449364
The outcome of children with intractable seizures: a 3- to 6-year follow-up of 67 children who remained on the ketogenic diet less than one year.Q34497520
Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic dietQ34542879
Brain function and chromatin plasticityQ34620395
Epigenetic mechanisms in cognitionQ34630009
Methylation regulates alpha-synuclein expression and is decreased in Parkinson's disease patients' brains.Q34660005
Alpha-synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseasesQ34685028
Brain S-adenosylmethionine levels are severely decreased in Alzheimer's diseaseQ34734276
Molecular insights into Parkinson's diseaseQ34988753
Dietary sulforaphane, a histone deacetylase inhibitor for cancer preventionQ35007040
The methionine-homocysteine cycle and its effects on cognitive diseasesQ35075332
Perspectives on the metabolic management of epilepsy through dietary reduction of glucose and elevation of ketone bodiesQ35177463
Ischemic insults promote epigenetic reprogramming of mu opioid receptor expression in hippocampal neuronsQ35676840
Intermittent fasting modulation of the diabetic syndrome in streptozotocin-injected ratsQ35691789
Histone variants, nucleosome assembly and epigenetic inheritanceQ35818464
Epigenetic mechanisms in memory formation.Q36011654
Neurotrophin signalling in health and diseaseQ36367776
Improvement in coronary heart disease risk factors during an intermittent fasting/calorie restriction regimen: Relationship to adipokine modulationsQ36444966
Epigenetics and epilepsy.Q36493159
A hundred years of Alzheimer's disease researchQ36610336
Epigenetics-Based Therapeutics for Neurodegenerative DisordersQ36697733
Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD.Q36793926
Genome-wide DNA methylation differences between late-onset Alzheimer's disease and cognitively normal controls in human frontal cortex.Q36838757
Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neuronsQ36965800
On the enzymatic properties of Dnmt1: specificity, processivity, mechanism of linear diffusion and allosteric regulation of the enzymeQ36983640
Mediterranean diet and mild cognitive impairmentQ37121952
Epigenetic mechanisms mediating the long-term effects of maternal care on development.Q37145451
The cell biology of DNA methylation in mammals.Q37245027
Alternate day fasting for weight loss in normal weight and overweight subjects: a randomized controlled trialQ37323187
Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseasesQ37332243
Decoding the epigenetic language of neuronal plasticityQ37358580
Expression of dense-core vesicles and of their exocytosis are governed by the repressive transcription factor NRSF/REST.Q37374910
Transcriptional and epigenetic functions of histone variant H2A.Z.Q37398592
The emerging field of neuroepigeneticsQ37425986
Epigenetic regulation in the pathophysiology of Alzheimer's diseaseQ37680418
Advances and perspectives from genetic research: development of biological markers in Alzheimer's diseaseQ37772498
Nutraceutical properties of Mediterranean diet and cognitive decline: possible underlying mechanisms.Q37790861
Epigenetic alterations associated with cellular senescence: a barrier against tumorigenesis or a red carpet for cancer?Q37938601
Applying epigenetics to Alzheimer's disease via the latent early-life associated regulation (LEARn) model.Q37980886
Epigenetic regulation of memory formation and maintenance.Q38074367
Epigenetic mechanisms in Alzheimer's disease: implications for pathogenesis and therapyQ38108084
Epigenetic targeting of histone deacetylase: therapeutic potential in Parkinson's disease?Q38109784
Interpreting the language of histone and DNA modificationsQ38196193
Rationale for using intermittent calorie restriction as a dietary treatment for drug resistant epilepsyQ38198419
The potential of epigenetic therapies in neurodegenerative diseasesQ38234971
Alzheimer's disease and epigenetic diet.Q38257632
The epigenetic basis of memory formation and storageQ38269734
The role of nutrient-based epigenetic changes in buffering against stress, aging, and Alzheimer's diseaseQ38278645
The emerging role of 5-hydroxymethylcytosine in neurodegenerative diseasesQ38299777
Naming from definition, semantic relevance and feature type: the effects of aging and Alzheimer's disease.Q38499254
Identification of the REST regulon reveals extensive transposable element-mediated binding site duplicationQ38517920
Protection of dopaminergic cells from MPP+-mediated toxicity by histone deacetylase inhibitionQ39676713
Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylationQ39802734
Valproic acid inhibits Abeta production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse modelsQ39924456
gamma-Secretase is differentially modulated by alterations of homocysteine cycle in neuroblastoma and glioblastoma cells.Q40081843
Influence of threonine metabolism on S-adenosylmethionine and histone methylationQ40648296
REST/NRSF-mediated intrinsic homeostasis protects neuronal networks from hyperexcitability.Q41825327
P921main subjectneurodegenerationQ1755122
P304page(s)58
P577publication date2015-02-27
P1433published inFrontiers in Cellular NeuroscienceQ2131509
P1476titleEpigenetic mechanisms in neurological and neurodegenerative diseases
P478volume9

Reverse relations

cites work (P2860)
Q39540210A systems biology-led insight into the role of the proteome in neurodegenerative diseases
Q47829315Advances in the Development of PET Ligands Targeting Histone Deacetylases for the Assessment of Neurodegenerative Diseases.
Q64764558Alpha-synuclein at the nexus of genes and environment: the impact of environmental enrichment and stress on brain health and disease
Q92603838Alzheimer's disease: pathogenesis, diagnostics, and therapeutics
Q43063864Anticonvulsant Effect of Time-Restricted Feeding in a Pilocarpine-Induced Seizure Model: Metabolic and Epigenetic Implications
Q92926139Characterizing Histone Post-translational Modification Alterations in Yeast Neurodegenerative Proteinopathy Models
Q37611722Contribution of Neuroepigenetics to Huntington's Disease.
Q90632433DNA Methylation in Neurodegenerative and Cerebrovascular Disorders
Q38762350Dad's Snoring May Have Left Molecular Scars in Your DNA: the Emerging Role of Epigenetics in Sleep Disorders
Q38711908Editing the genome of hiPSC with CRISPR/Cas9: disease models
Q42259466Effect of methotrexate/vitamin B12 on DNA methylation as a potential factor in leukemia treatment-related neurotoxicity
Q64071921Epigenetic Analysis in Human Neurons: Considerations for Disease Modeling in PD
Q38993596Epigenetic Biomarkers for Parkinson's Disease: From Diagnostics to Therapeutics.
Q38686112Exercise and Nutritional Benefits in PD: Rodent Models and Clinical Settings
Q28069705Incorporating Natural Products, Pharmaceutical Drugs, Self-Care and Digital/Mobile Health Technologies into Molecular-Behavioral Combination Therapies for Chronic Diseases
Q37683341Lysine Acetylation and Deacetylation in Brain Development and Neuropathies
Q26747013MeCP2 and the enigmatic organization of brain chromatin. Implications for depression and cocaine addiction
Q52369540Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin.
Q60946456NRSF and Its Epigenetic Effectors: New Treatments for Neurological Disease
Q39076065Network Analysis Identifies Disease-Specific Pathways for Parkinson's Disease
Q47290734Neurodegenerative Disease Proteinopathies Are Connected to Distinct Histone Post-translational Modification Landscapes.
Q48024631Nutritional habits, risk, and progression of Parkinson disease
Q37065788Pathogenic Mutations in the Valosin-containing Protein/p97(VCP) N-domain Inhibit the SUMOylation of VCP and Lead to Impaired Stress Response
Q58555658Pharmacoepigenomic Interventions as Novel Potential Treatments for Alzheimer's and Parkinson's Diseases
Q98726168Poly (I:C) Exposure in Early Life Alters Methylation of DNA and Acetylation of Histone at Synaptic Plasticity Gene Promoter in Developing Rat Brain Leading to Memory Impairment
Q92354306Precision Medicine in Neurodegenerative Diseases: Some Promising Tips Coming from the microRNAs' World
Q90640897Protective effects of histone deacetylase inhibition by Scriptaid on brain injury in neonatal rat models of cerebral ischemia and hypoxia
Q94601317QSAR-driven rational design of novel DNA methyltransferase 1 inhibitors
Q38820807Recent Findings in Alzheimer Disease and Nutrition Focusing on Epigenetics
Q42926328Reshaping the Chromatin and Epigenetic Landscapes with Quantitative Mass Spectrometry
Q37699534Stress and the Emerging Roles of Chromatin Remodeling in Signal Integration and Stable Transmission of Reversible Phenotypes.
Q39313679The emerging field of epigenetics in neurodegeneration and neuroprotection
Q37369669Whole-Genome DNA Methylation Analysis of Peripheral Blood Mononuclear Cells in Multiple Sclerosis Patients with Different Disease Courses
Q39311565β-Hydroxybutyrate: A Signaling Metabolite.

Search more.