Dysregulation of histone acetylation in the APP/PS1 mouse model of Alzheimer's disease.

scientific article published in January 2009

Dysregulation of histone acetylation in the APP/PS1 mouse model of Alzheimer's disease. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3233/JAD-2009-1134
P698PubMed publication ID19625751

P50authorMauro FàQ43127464
Ottavio ArancioQ57733929
P2093author name stringHong Zhang
David S Latchman
Yitshak I Francis
Agnieszka Staniszewski
Haider Ashraf
P433issue1
P921main subjecthistone acetylationQ14908264
P304page(s)131-139
P577publication date2009-01-01
P1433published inJournal of Alzheimer's DiseaseQ6294755
P1476titleDysregulation of histone acetylation in the APP/PS1 mouse model of Alzheimer's disease.
P478volume18

Reverse relations

cites work (P2860)
Q35590452'Relax and Repair' to restrain aging.
Q47578572Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer's disease.
Q50993017Alzheimer's Disease and Histone Code Alterations.
Q92603838Alzheimer's disease: pathogenesis, diagnostics, and therapeutics
Q37228171An Integrated Human/Murine Transcriptome and Pathway Approach To Identify Prenatal Treatments For Down Syndrome
Q26858963Behavioral assays with mouse models of Alzheimer's disease: practical considerations and guidelines
Q38676090Chromatin Changes Associated with Neuronal Maintenance and Their Pharmacological Application
Q34342179Chromatin remodeling, DNA damage repair and aging.
Q37361621Chromatin structure and transposable elements in organismal aging
Q47567142Co-location of HDAC2 and insulin signaling components in the adult mouse hippocampus
Q26774368Computational Modelling Approaches on Epigenetic Factors in Neurodegenerative and Autoimmune Diseases and Their Mechanistic Analysis
Q41635420Detection of histone acetylation levels in the dorsal hippocampus reveals early tagging on specific residues of H2B and H4 histones in response to learning.
Q101237411Disruption of Tip60 HAT mediated neural histone acetylation homeostasis is an early common event in neurodegenerative diseases
Q47866794Drebrin in Alzheimer's Disease.
Q48018264Early Preclinical Changes in Hippocampal CREB-Binding Protein Expression in a Mouse Model of Familial Alzheimer's Disease.
Q42396584Environmental enrichment: aging and memory.
Q38199061Environmental factors in the development and progression of late-onset Alzheimer's disease
Q26770475Epigenetic Alterations in Alzheimer's Disease
Q28075559Epigenetic Changes in Neurodegenerative Diseases
Q64263723Epigenetic Modifications in Alzheimer's Neuropathology and Therapeutics
Q35753421Epigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging
Q34294750Epigenetic histone acetylation and deacetylation mechanisms in experimental models of neurodegenerative disorders
Q33858861Epigenetic mechanisms during ageing and neurogenesis as novel therapeutic avenues in human brain disorders.
Q83829640Epigenetic mechanisms in Alzheimer's disease
Q97570185Epigenetic mechanisms in Alzheimer's disease
Q38379396Epigenetic mechanisms in neurological and neurodegenerative diseases
Q34323841Epigenetic memory: the Lamarckian brain
Q47564897Epigenetic regulation of astrocyte function in neuroinflammation and neurodegeneration
Q37870034Epigenetic regulation of gene expression in physiological and pathological brain processes
Q38207893Epigenetic regulation of memory by acetylation and methylation of chromatin: implications in neurological disorders, aging, and addiction
Q35185570Epigenetic regulations of immediate early genes expression involved in memory formation by the amyloid precursor protein of Alzheimer disease
Q26772028Epigenetics of Aging and Alzheimer's Disease: Implications for Pharmacogenomics and Drug Response
Q39317395Epigenome Editing in the Brain
Q85263415Epigenomic networking in drug development: from pathogenic mechanisms to pharmacogenomics
Q36998001Genes and epigenetic processes as prospective pain targets
Q48322973Genetic sensitivity to the environment, across lifetime
Q48186683HDAC inhibition facilitates the switch between memory systems in young but not aged mice
Q41608936HDAC inhibitor-dependent transcriptome and memory reinstatement in cognitive decline models.
Q41628820HDAC3 negatively regulates spatial memory in a mouse model of Alzheimer's disease
Q38542044Histone Acetylation Modifiers in the Pathogenesis of Alzheimer's Disease
Q55008077Histone Deacetylase Inhibitor Alleviates the Neurodegenerative Phenotypes and Histone Dysregulation in Presenilins-Deficient Mice.
Q92927460Histone Deacetylase Inhibitors as Multitarget Ligands: New Players in Alzheimer's Disease Drug Discovery?
Q35134204Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice
Q34322979Histone acetylation: molecular mnemonics on the chromatin.
Q30440318Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition.
Q36140656Histone modifications change with age, dietary restriction and rapamycin treatment in mouse brain
Q38227853Histone-acetylation: a link between Alzheimer's disease and post-traumatic stress disorder?
Q35748624Increased EID1 nuclear translocation impairs synaptic plasticity and memory function associated with pathogenesis of Alzheimer's disease
Q30498541Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease
Q36939128Is the amyloid hypothesis of Alzheimer's disease therapeutically relevant?
Q45305295Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity.
Q38085375Lysine acetyltransferases CBP and p300 as therapeutic targets in cognitive and neurodegenerative disorders.
Q28080843Molecular mechanisms of synaptic remodeling in alcoholism
Q51629038Multiplex detection of histone-modifying enzymes by total internal reflection fluorescence-based single-molecule detection.
Q35558250Neonatal isoflurane exposure induces neurocognitive impairment and abnormal hippocampal histone acetylation in mice
Q37238365Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway.
Q47319962Neuroprotective effects of artemisinin against isoflurane-induced cognitive impairments and neuronal cell death involve JNK/ERK1/2 signalling and improved hippocampal histone acetylation in neonatal rats
Q39196413Oral administration of histone deacetylase inhibitor MS-275 ameliorates neuroinflammation and cerebral amyloidosis and improves behavior in a mouse model.
Q93080138Pan-HDAC Inhibitors Promote Tau Aggregation by Increasing the Level of Acetylated Tau
Q29994749Paternal spatial training enhances offspring's cognitive performance and synaptic plasticity in wild-type but not improve memory deficit in Alzheimer's mice
Q58555658Pharmacoepigenomic Interventions as Novel Potential Treatments for Alzheimer's and Parkinson's Diseases
Q34970563Phenyl acyl acids attenuate the unfolded protein response in tunicamycin-treated neuroblastoma cells
Q43648215Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease
Q45954200Phosphodiesterase 5 inhibition improves synaptic function, memory, and amyloid-beta load in an Alzheimer's disease mouse model.
Q41661244Post-training, intrahippocampal HDAC inhibition differentially impacts neural circuits underlying spatial memory in adult and aged mice
Q38718079Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits
Q35485587Potential non-oncological applications of histone deacetylase inhibitors
Q38041123Potential of chromatin modifying compounds for the treatment of Alzheimer's disease
Q37872394Probing the role of HDACs and mechanisms of chromatin-mediated neuroplasticity
Q30535298Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease
Q48150943Region- and age-specific patterns of histone acetylation related to spatial and cued learning in the water maze
Q36574016Regulation of Histone Acetylation by Autophagy in Parkinson Disease
Q34905146SAHA enhances synaptic function and plasticity in vitro but has limited brain availability in vivo and does not impact cognition
Q28834522Site-specific quantification of lysine acetylation in the N-terminal tail of histone H4 using a double-labelling, targeted UHPLC MS/MS approach
Q28564318Spatial memory consolidation is associated with induction of several lysine-acetyltransferase (histone acetyltransferase) expression levels and H2B/H4 acetylation-dependent transcriptional events in the rat hippocampus.
Q36097888Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, attenuates postoperative cognitive dysfunction in aging mice
Q93083881Synaptic and memory dysfunction induced by tau oligomers is rescued by up-regulation of the nitric oxide cascade
Q35064948Synaptic therapy in Alzheimer's disease: a CREB-centric approach
Q44787901Targeted proteomics for quantification of histone acetylation in Alzheimer's disease.
Q35224092Targeting HDACs: a promising therapy for Alzheimer's disease.
Q26771812Targeting New Candidate Genes by Small Molecules Approaching Neurodegenerative Diseases
Q38094663Targeting specific HATs for neurodegenerative disease treatment: translating basic biology to therapeutic possibilities
Q38036916Targeting synaptic dysfunction in Alzheimer's disease therapy.
Q57072881The Contribution and Therapeutic Potential of Epigenetic Modifications in Alzheimer's Disease
Q90704728The Hyperactivity-Impulsivity-Irritiability-Disinhibition-Aggression-Agitation Domain in Alzheimer's Disease: Current Management and Future Directions
Q36223734The Role of DNA Methylation and Histone Modifications in Neurodegenerative Diseases: A Systematic Review
Q38793903The Vitamin A Derivative All-Trans Retinoic Acid Repairs Amyloid-β-Induced Double-Strand Breaks in Neural Cells and in the Murine Neocortex
Q34426210The epigenetic dimension of Alzheimer's disease: causal, consequence, or curiosity?
Q38527233The epigenetics of aging and neurodegeneration.
Q38234971The potential of epigenetic therapies in neurodegenerative diseases
Q37978548The role of clusterin in Alzheimer's disease: pathways, pathogenesis, and therapy
Q42149605Transcriptional signatures mediated by acetylation overlap with early-stage Alzheimer's disease
Q34137377Tuning acetylation levels with HAT activators: Therapeutic strategy in neurodegenerative diseases
Q51779584Using induced pluripotent stem cells to explore genetic and epigenetic variation associated with Alzheimer's disease.
Q48710262Valproate improves memory deficits in an Alzheimer's disease mouse model: investigation of possible mechanisms of action

Search more.