Regulation of autophagy in human skeletal muscle: effects of exercise, exercise training and insulin stimulation.

scientific article published on 15 January 2016

Regulation of autophagy in human skeletal muscle: effects of exercise, exercise training and insulin stimulation. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1113/JP271405
P932PMC publication ID5341711
P698PubMed publication ID26614120
P5875ResearchGate publication ID285044014

P50authorErik A RichterQ42164127
Thomas Elbenhardt JensenQ47452518
Andreas Mæchel FritzenQ49992336
Agnete B MadsenQ55437058
Jonas T. TreebakQ55437064
Maximilian KleinertQ55728436
Jørgen WojtaszewskiQ57339852
Anne-Marie LundsgaardQ60737495
Bente KiensQ61820615
Christian FrøsigQ114388013
P2860cites workGuidelines for the use and interpretation of assays for monitoring autophagyQ21996341
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagyQ24312147
Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasisQ24601575
Physical exercise stimulates autophagy in normal skeletal muscles but is detrimental for collagen VI-deficient musclesQ24629897
mTOR: from growth signal integration to cancer, diabetes and ageingQ24633662
Isoform-specific and exercise intensity-dependent activation of 5'-AMP-activated protein kinase in human skeletal muscleQ24651012
AKT/PKB signaling: navigating downstreamQ24657857
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Autophagy in the Pathogenesis of DiseaseQ27860558
Transcriptional regulation of gene expression in human skeletal muscle during recovery from exerciseQ28139373
A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscleQ28199222
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1Q28506431
AMP-activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscleQ28592195
Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exerciseQ28610612
Autophagy: renovation of cells and tissuesQ29547206
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell deathQ29547297
How to interpret LC3 immunoblottingQ29614175
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagyQ29615616
mTOR regulation of autophagyQ29616301
The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosisQ29622875
Autophagy is required for exercise training-induced skeletal muscle adaptation and improvement of physical performanceQ30410425
Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation.Q33695751
The association of AMPK with ULK1 regulates autophagyQ33745164
Exercise ameliorates the detrimental effect of chloroquine on skeletal muscles in mice via restoring autophagy fluxQ33824545
Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance.Q33896647
Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivoQ34080562
Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).Q34139142
5'-AMP-activated protein kinase activity and protein expression are regulated by endurance training in human skeletal muscleQ34276280
Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathyQ34340407
Autophagy: assays and artifactsQ34341096
Effects of exercise training on in vivo insulin action in individual tissues of the rat.Q34548232
Effects of endurance exercise training on insulin signaling in human skeletal muscle: interactions at the level of phosphatidylinositol 3-kinase, Akt, and AS160.Q34629950
Activation of AMPKα2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrityQ35147707
Fasting increases human skeletal muscle net phenylalanine release and this is associated with decreased mTOR signalingQ35206436
Role of PGC-1α during acute exercise-induced autophagy and mitophagy in skeletal muscleQ35572598
Induction and adaptation of chaperone-assisted selective autophagy CASA in response to resistance exercise in human skeletal muscleQ35852833
Prophylactic effects of swimming exercise on autophagy-induced muscle atrophy in diabetic ratsQ36313229
Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle.Q36767833
Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe diseaseQ37089630
TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells.Q37151507
AMPK activation of muscle autophagy prevents fasting-induced hypoglycemia and myopathy during agingQ37583673
PT-1 selectively activates AMPK-γ1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chainQ38908127
AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1.Q39456716
Quantitation of "autophagic flux" in mature skeletal muscleQ39676193
Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagyQ40250473
Muscle glucose metabolism following exercise in the rat: increased sensitivity to insulinQ40680853
Physical exercise increases autophagic signaling through ULK1 in human skeletal muscleQ41440701
AMPK binds to Sestrins and mediates the effect of exercise to increase insulin-sensitivity through autophagyQ42472781
Autophagic adaptation is associated with exercise-induced fibre-type shifting in skeletal muscle.Q42475257
Markers of autophagy are adapted to hyperglycaemia in skeletal muscle in type 2 diabetesQ42477947
Higher activation of autophagy in skeletal muscle of mice during endurance exercise in the fasted stateQ44183860
Insulin action in cultured human skeletal muscle cells during differentiation: assessment of cell surface GLUT4 and GLUT1 content.Q44491912
Acute exercise and physiological insulin induce distinct phosphorylation signatures on TBC1D1 and TBC1D4 proteins in human skeletal muscleQ44609387
Autophagy and protein turnover signaling in slow-twitch muscle during exercise.Q45238955
In search of an "autophagomometer".Q46027342
Reduced malonyl-CoA content in recovery from exercise correlates with improved insulin-stimulated glucose uptake in human skeletal muscleQ46135106
Acute environmental hypoxia induces LC3 lipidation in a genotype-dependent manner.Q46448475
Dihydromyricetin improves skeletal muscle insulin sensitivity by inducing autophagy via the AMPK-PGC-1α-Sirt3 signaling pathway.Q48198036
Activation of autophagy in human skeletal muscle is dependent on exercise intensity and AMPK activation.Q50979292
Autophagy is required to maintain muscle mass.Q51411361
Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats.Q54448884
Modulation of autophagy and ubiquitin-proteasome pathways during ultra-endurance running.Q54528865
AMP-activated Protein Kinase and the Regulation of Autophagic ProteolysisQ56777095
Autophagy is defective in collagen VI muscular dystrophies and its reactivation rescues myofiber degenerationQ57639972
Effect of endurance exercise training on Ca2+ calmodulin-dependent protein kinase II expression and signalling in skeletal muscle of humansQ58172064
Exercise improves phosphatidylinositol-3,4,5-trisphosphate responsiveness of atypical protein kinase C and interacts with insulin signalling to peptide elongation in human skeletal muscleQ58172078
Possible CaMKK-dependent regulation of AMPK phosphorylation and glucose uptake at the onset of mild tetanic skeletal muscle contractionQ58172102
Effect of exercise on insulin action in human skeletal muscleQ58172564
Dynamic knee extension as model for study of isolated exercising muscle in humansQ60686303
Selective glycogen depletion pattern in human muscle fibres after exercise of varying intensity and at varying pedalling ratesQ68536014
Prolonged increase in insulin-stimulated glucose transport in muscle after exerciseQ69494981
Insulin-Stimulated Muscle Glucose Clearance in Patients With NIDDM: Effects of One-Legged Physical TrainingQ72015336
Insulin signaling in human skeletal muscle: time course and effect of exerciseQ73842120
Insulin signaling and insulin sensitivity after exercise in human skeletal muscleQ73929114
Sarcolemmal glucose transport and GLUT-4 translocation during exercise are diminished by endurance trainingQ74153574
Predominant alpha2/beta2/gamma3 AMPK activation during exercise in human skeletal muscleQ79233726
Autophagic response to a single bout of moderate exercise in murine skeletal muscleQ83150547
Autophagic response to exercise training in skeletal muscle with ageQ86313856
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectautophagyQ288322
P304page(s)745-761
P577publication date2016-01-15
P1433published inJournal of PhysiologyQ7743612
P1476titleRegulation of autophagy in human skeletal muscle: effects of exercise, exercise training and insulin stimulation.
P478volume594

Reverse relations

cites work (P2860)
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