Dietary n-3 PUFA increases the apoptotic response to 1,2-dimethylhydrazine, reduces mitosis and suppresses the induction of carcinogenesis in the rat colon.

scientific article published in April 1999

Dietary n-3 PUFA increases the apoptotic response to 1,2-dimethylhydrazine, reduces mitosis and suppresses the induction of carcinogenesis in the rat colon. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/CARCIN/20.4.645
P698PubMed publication ID10223194
P5875ResearchGate publication ID13075651

P50authorIan T JohnsonQ41540195
P2093author name stringLund EK
Latham P
P2860cites workRelationship between dose, time, and tumor yield in mouse dimethylhydrazine-induced colon tumorigenesisQ28328506
Prostaglandins from tumours of human large bowelQ36069396
Role of aberrant crypt foci in understanding the pathogenesis of colon cancerQ40438443
Evidence that changes in Se-glutathione peroxidase levels affect the sensitivity of human tumour cell lines to n-3 fatty acidsQ41080188
Inhibition of dimethylhydrazine-induced aberrant crypt foci and induction of apoptosis in rat colon following oral administration of the glucosinolate sinigrin.Q52529483
Predictive value of proliferation, differentiation and apoptosis as intermediate markers for colon tumorigenesis.Q53444563
Polyunsaturated fatty acids of the n - 3 series influence intestinal crypt cell production in rats.Q53471954
A possible explanation for the differential cancer incidence in the intestine, based on distribution of the cytotoxic effects of carcinogens in the murine large bowelQ53485594
Can tumour cell drug resistance be reversed by essential fatty acids and their metabolites?Q54146198
Development of aberrant crypt foci involves a fission mechanism as revealed by isolation of aberrant crypts.Q55351769
Dietary fat and fiber differentially alter intracellular second messengers during tumor devolopment in rat colonQ58450286
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
carcinogenesisQ1637543
P304page(s)645-650
P577publication date1999-04-01
P1433published inCarcinogenesisQ326022
P1476titleDietary n-3 PUFA increases the apoptotic response to 1,2-dimethylhydrazine, reduces mitosis and suppresses the induction of carcinogenesis in the rat colon.
P478volume20

Reverse relations

cites work (P2860)
Q34983024A chemoprotective fish oil- and pectin-containing diet temporally alters gene expression profiles in exfoliated rat colonocytes throughout oncogenesis.
Q51668930A comparison of the effects of soya isoflavonoids and fish oil on cell proliferation, apoptosis and the expression of oestrogen receptors alpha and beta in the mammary gland and colon of the rat.
Q33791932Alterations in lipid mediated signaling and Wnt/ β -catenin signaling in DMH induced colon cancer on supplementation of fish oil.
Q81731338An enhanced apoptosis and a reduced angiogenesis are associated with the inhibition of lung colonisation in animals fed an n-3 polyunsaturated fatty acid-rich diet injected with a highly metastatic murine melanoma line
Q34687944Anticarcinogenic effects of diet-related apoptosis in the colorectal mucosa.
Q53098952Apoptosis-Mediated Chemoprevention by Different Ratios of Fish Oil in Experimental Colon Carcinogenesis.
Q42511906Beef tallow, but not perilla or corn oil, promotion of rat prostate and intestinal carcinogenesis by 3,2'-dimethyl-4-aminobiphenyl
Q90346571Chemoprevention of Colorectal Cancer
Q42926809Chemopreventive effect of different ratios of fish oil and corn oil in experimental colon carcinogenesis
Q34107914Diet and prevention of colorectal cancer
Q43927554Dietary n-3 PUFA alter colonocyte mitochondrial membrane composition and function
Q61908082Dietary omega-3-polyunsaturated fatty acids prevent the development of metastases of colon carcinoma in rat liver
Q33789686Dietary polyunsaturated fatty acids and cancers of the breast and colorectum: emerging evidence for their role as risk modifiers
Q35005048Dietary polyunsaturated fatty acids and colorectal neoplasia.
Q43600427Docosahexaenoic acid induces apoptosis in Jurkat cells by a protein phosphatase-mediated process
Q40903079Effect of eicosapentaenoic acid on the proliferation and incidence of apoptosis in the colorectal cell line HT29.
Q35359099Effect of olive oil on early and late events of colon carcinogenesis in rats: modulation of arachidonic acid metabolism and local prostaglandin E(2) synthesis
Q28367055Effects of cellular redox balance on induction of apoptosis by eicosapentaenoic acid in HT29 colorectal adenocarcinoma cells and rat colon in vivo
Q44620524Effects of high fat fish oil and high fat corn oil diets on initiation of AOM-induced colonic aberrant crypt foci in male F344 rats
Q79537453Eicosapentaenoic acid (EPA) reduces crypt cell proliferation and increases apoptosis in normal colonic mucosa in subjects with a history of colorectal adenomas
Q34658888Fatty acid oxidation and signaling in apoptosis
Q37452775Fish oil suppresses cell growth and metastatic potential by regulating PTEN and NF-κB signaling in colorectal cancer
Q42633983Identification of the Eph receptor pathway as a novel target for eicosapentaenoic acid (EPA) modification of gene expression in human colon adenocarcinoma cells (HT-29).
Q40888157Incorporation of polyunsaturated fatty acids into CT-26, a transplantable murine colonic adenocarcinoma.
Q34011596Increased induction of apoptosis by Propionibacterium freudenreichii TL133 in colonic mucosal crypts of human microbiota-associated rats treated with 1,2-dimethylhydrazine
Q73261438Increased intake of n-3 polyunsaturated fatty acids elevates the level of apoptosis in the normal sigmoid colon of patients polypectomized for adenomas/tumors
Q33880883Intake of polyunsaturated fatty acids and distal large bowel cancer risk in whites and African Americans
Q35033649Integrated microRNA and mRNA expression profiling in a rat colon carcinogenesis model: effect of a chemo-protective diet
Q57100225Intestinal homeostasis is restored in mice following a period of intestinal growth induced by orally administered Emu Oil
Q37653000Long-chain omega-3 polyunsaturated fatty acid intake and risk of colorectal cancer.
Q53676958Mechanisms and anticarcinogenic effects of diet-related apoptosis in the intestinal mucosa.
Q37124176Modulation of gene expression in eicosapentaenoic acid and docosahexaenoic acid treated human colon adenoma cells
Q24650990Most effective colon cancer chemopreventive agents in rats: a systematic review of aberrant crypt foci and tumor data, ranked by potency
Q33933860Nutritional support of the cancer patient: issues and dilemmas
Q34459046Omega-3 fatty acid is a potential preventive agent for recurrent colon cancer
Q36781253Peroxisome proliferator activated receptor α ligands as anticancer drugs targeting mitochondrial metabolism
Q41661897Potential Application of Eicosapentaenoic Acid Monoacylglyceride in the Management of Colorectal Cancer
Q38718929Prevention and treatment of cancers by immune modulating nutrients.
Q43832512Prevention of docosahexaenoic acid-induced cytotoxicity by phosphatidic acid in Jurkat leukemic cells: the role of protein phosphatase-1.
Q41456639Proapoptotic effects of dietary (n-3) fatty acids are enhanced in colonocytes of manganese-dependent superoxide dismutase knockout mice.
Q46880252Protective effects of diets supplemented with omega-3 polyunsaturated fatty acids and calcium against colorectal tumor formation
Q36325748Protein kinase C betaII and TGFbetaRII in omega-3 fatty acid-mediated inhibition of colon carcinogenesis
Q37222037Regulation of colorectal cancer cell apoptosis by the n-3 polyunsaturated fatty acids Docosahexaenoic and Eicosapentaenoic.
Q34141413Review: the role of omega 3 fatty acids in intestinal inflammation
Q35785440Role of omega-3 fatty acid supplementation in inflammation and malignancy
Q28345953Severe imbalance of cell proliferation and apoptosis in the left colon and in the rectosigmoid tract in subjects with a history of large adenomas
Q42495557Sustained proliferation and resistance to apoptosis after a cytotoxic insult are early alterations in rat colon carcinogenesis
Q37295891The inhibitory effect of dibutyryl cyclic AMP on docosahexaenoic acid-induced apoptosis in HL-60 cells through activation of the phosphatidylinositol-3 kinase pathway
Q36166684The omega-3 polyunsaturated fatty acid eicosapentaenoic acid inhibits mouse MC-26 colorectal cancer cell liver metastasis via inhibition of PGE2-dependent cell motility
Q79133097[Role of dietary lipids in the mechanisms of inflammation, proliferation, differentiation and cell death in the gastrointestinal tract]
Q36648366n-3 polyunsaturated fatty acids decrease mucosal/epidermal reactions and enhance antitumour effect of ionising radiation with inhibition of tumour angiogenesis

Search more.