| scholarly article | Q13442814 |
| P356 | DOI | 10.1006/EXCR.1997.3670 |
| P953 | full work available at URL | https://api.elsevier.com/content/article/PII:S0014482797936703?httpAccept=text/plain |
| https://api.elsevier.com/content/article/PII:S0014482797936703?httpAccept=text/xml | ||
| P698 | PubMed publication ID | 9281374 |
| P2093 | author name string | C. C. Harris | |
| J. W. Shay | |||
| W. P. Bennett | |||
| J. D. Coursen | |||
| L. Gollahon | |||
| P2860 | cites work | Cancer Research | Q326097 |
| BioTechniques | Q4914664 | ||
| The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 | Q24317677 | ||
| Telomere elongation in immortal human cells without detectable telomerase activity | Q24598626 | ||
| Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction | Q25938986 | ||
| Specific Association of Human Telomerase Activity with Immortal Cells and Cancer | Q27860801 | ||
| Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription | Q28187745 | ||
| p53 mutations in human cancers | Q28302973 | ||
| The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53 | Q29547773 | ||
| Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity | Q29615388 | ||
| p53: puzzle and paradigm | Q29618407 | ||
| A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F | Q29620241 | ||
| The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein | Q33938629 | ||
| Enhanced degradation of p53 protein in HPV-6 and BPV-1 E6-immortalized human mammary epithelial cells. | Q34050026 | ||
| Abnormal centrosome amplification in the absence of p53. | Q34374717 | ||
| Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7. | Q35230883 | ||
| A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18 | Q35937193 | ||
| Metastatic conversion of cells by expression of human papillomavirus type 16 E6 and E7 genes | Q36417356 | ||
| Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts | Q36554262 | ||
| Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines | Q36556649 | ||
| Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells | Q36645358 | ||
| Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. | Q36660357 | ||
| The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cells | Q36688177 | ||
| Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts | Q36770102 | ||
| Loss of p53 protein in human papillomavirus type 16 E6-immortalized human mammary epithelial cells | Q36828231 | ||
| Chromosome 1 aberrations in cancer | Q39729490 | ||
| Modifications of a telomeric repeat amplification protocol (TRAP) result in increased reliability, linearity and sensitivity | Q40395982 | ||
| Telomerase activity in human cancer. | Q41161808 | ||
| Telomerase activation by the E6 gene product of human papillomavirus type 16. | Q41218028 | ||
| Quantitation of the frequency of immortalization of normal human diploid fibroblasts by SV40 large T-antigen | Q41272620 | ||
| HPV-16 E6 and E7 genes, like SV40 early region genes, are insufficient for immortalization of human mesothelial and bronchial epithelial cells | Q41450325 | ||
| Elevated wild-type p53 protein levels in human epithelial cell lines immortalized by the human papillomavirus type 16 E7 gene | Q41497722 | ||
| Cytogenetic analysis of eight human papillomavirus immortalized human keratinocyte cell lines | Q41758172 | ||
| Association of human papillomavirus types 16 and 18 E6 proteins with p53. | Q43701619 | ||
| Telomere positional effects and the regulation of cellular senescence | Q68007322 | ||
| Association between poor prognosis in early-stage invasive cervical carcinomas and non-detection of HPV DNA | Q68087656 | ||
| Human papillomavirus in clinically and histologically normal tissue of patients with genital cancer | Q70148783 | ||
| Cytogenetic findings in cervical carcinoma. A statistical approach | Q70162117 | ||
| Transcriptional control and cell type specificity of HPV gene expression | Q72765415 | ||
| Massively parallel sequencing analysis of 68 gastric-type cervical adenocarcinomas reveals mutations in cell cycle-related genes and potentially targetable mutations | Q104471902 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | transcription | Q177900 |
| chromosome abnormality | Q744962 | ||
| dysplasia | Q1128996 | ||
| repressor proteins | Q66764508 | ||
| human papilloma virus | Q69999790 | ||
| P304 | page(s) | 245-253 | |
| P577 | publication date | 1997-08-01 | |
| 1997-08-25 | |||
| P1433 | published in | Experimental Cell Research | Q1524289 |
| P1476 | title | Genomic Instability and Telomerase Activity in Human Bronchial Epithelial Cells during Immortalization by Human Papillomavirus-16 E6 and E7 Genes | |
| P478 | volume | 235 |
| Q86630527 | Age-associated decreases in human DNA repair capacity: Implications for the skin |
| Q36771826 | BRCA1/2 mutations perturb telomere biology: characterization of structural and functional abnormalities in vitro and in vivo |
| Q40973006 | C-myc overexpression and p53 loss cooperate to promote genomic instability |
| Q54639515 | Detecting cell-free circulating hTERT mRNA in the plasma may identify a subset of nonsmall cell lung cancer patients. |
| Q40079202 | Differentiation potential of a basal epithelial cell line established from human bronchial explant |
| Q63583250 | E6/E7 oncogenes increase and tumor suppressors decrease the proportion of self-renewing neural progenitor cells |
| Q40006841 | Establishment of immortalized human hepatocytes by introduction of HPV16 E6/E7 and hTERT as cell sources for liver cell-based therapy |
| Q59017675 | Generation of Immortalised But Unstable Cells after hTERT Introduction in Telomere-Compromised and p53-Deficient vHMECs |
| Q40865861 | Genetic characterization of immortalized human prostate epithelial cell cultures. Evidence for structural rearrangements of chromosome 8 and i(8q) chromosome formation in primary tumor-derived cells |
| Q35020487 | Genomic Instability Induced By Human Papillomavirus Oncogenes |
| Q35013671 | HPV infections and lung cancer |
| Q33653268 | Immortalization of chicken preadipocytes by retroviral transduction of chicken TERT and TR. |
| Q38522460 | Immortalization of normal adult human middle ear epithelial cells using a retrovirus containing the E6/E7 genes of human papillomavirus type 16. |
| Q35642280 | Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins |
| Q38526539 | Notch activation is associated with tetraploidy and enhanced chromosomal instability in meningiomas |
| Q38218749 | Strategies for immortalization of primary hepatocytes |
| Q35628573 | Telomeres, stem cells, senescence, and cancer |
| Q77357062 | The cells are mortal or immortal, divide and disappear with reincarnation or after metabolic or apoptotic death |
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