| scholarly article | Q13442814 |
| P356 | DOI | 10.1128/MCB.16.1.53 |
| P8608 | Fatcat ID | release_owveuru3rbecpgjd6eippot55m |
| P932 | PMC publication ID | 230978 |
| P698 | PubMed publication ID | 8524329 |
| P50 | author | Elizabeth Blackburn | Q26321 |
| P2093 | author name string | C Strahl | |
| P2860 | cites work | The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats | Q24339608 |
| Specific Association of Human Telomerase Activity with Immortal Cells and Cancer | Q27860801 | ||
| A mutant with a defect in telomere elongation leads to senescence in yeast | Q27930429 | ||
| Identification of a specific telomere terminal transferase activity in Tetrahymena extracts | Q28306745 | ||
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| Telomeres shorten during ageing of human fibroblasts | Q29547357 | ||
| Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection | Q29547852 | ||
| Viral dynamics in human immunodeficiency virus type 1 infection | Q29547908 | ||
| A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis | Q29614741 | ||
| Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity | Q29615388 | ||
| Structure and function of telomeres | Q29615759 | ||
| An alternative pathway for yeast telomere maintenance rescues est1- senescence | Q29616135 | ||
| A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes | Q29617061 | ||
| TLC1: template RNA component of Saccharomyces cerevisiae telomerase | Q29618197 | ||
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| Functional Evidence for an RNA Template in Telomerase | Q33998306 | ||
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| Telomere dynamics in an immortal human cell line | Q34059767 | ||
| Developmental and tissue-specific regulation of mouse telomerase and telomere length | Q34265760 | ||
| Structure and variability of human chromosome ends | Q34419028 | ||
| Telomeric repeat from T. thermophila cross hybridizes with human telomeres | Q34554038 | ||
| The effects of nucleoside analogs on telomerase and telomeres in Tetrahymena | Q34810908 | ||
| Activation of telomerase in a human tumor | Q35141128 | ||
| Telomerase activity in human ovarian carcinoma | Q35142569 | ||
| Non-nucleosomal packaging of a tandemly repeated DNA sequence at termini of extrachromosomal DNA coding for rRNA in Tetrahymena | Q35346090 | ||
| Specific RNA residue interactions required for enzymatic functions of Tetrahymena telomerase | Q36556655 | ||
| Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells | Q36645358 | ||
| Genetic control of chromosome length in yeast | Q37675319 | ||
| Telomeres: no end in sight | Q40763655 | ||
| Two human breast cancer cell lines showing decreasing telomeric repeat length during early in vitro passaging | Q41438686 | ||
| Structure and polymorphism of human telomere-associated DNA. | Q41718575 | ||
| Maintenance of multiplication rate stability by cell populations in the face of heterogeneity among individual cells. | Q42801284 | ||
| Runaway telomere elongation caused by telomerase RNA gene mutations | Q46144742 | ||
| Altering specific telomerase RNA template residues affects active site function | Q46211302 | ||
| In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs | Q46821624 | ||
| Telomere end-replication problem and cell aging | Q56508218 | ||
| Telomere telomere recombination provides an express pathway for telomere acquisition | Q59007196 | ||
| Dynamics of telomere length variation in tetrahymena thermophila | Q62659441 | ||
| Terminal deoxynucleotidyl transferase activity in human leukemic cells and in normal human thymocytes | Q66840859 | ||
| Growth of chromosome ends in multiplying trypanosomes | Q67297495 | ||
| Telomere proteins: specific recognition and protection of the natural termini of Oxytricha macronuclear DNA | Q70308671 | ||
| Telomere length variation in normal and malignant human tissues | Q71670309 | ||
| Correlating telomerase activity levels with human neuroblastoma outcomes | Q71803058 | ||
| Telomeric associations and loss of telomeric DNA repeats in renal tumors | Q72076160 | ||
| Telomerase activity in vivo in human malignant hematopoietic cells | Q72185116 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | telomere length | Q59658244 |
| P304 | page(s) | 53-65 | |
| P577 | publication date | 1996-01-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines | |
| P478 | volume | 16 |
| Q36328924 | 3'-Azido-2',3'-dideoxynucleoside 5'-triphosphates inhibit telomerase activity in vitro, and the corresponding nucleosides cause telomere shortening in human HL60 cells |
| Q53427484 | 9-Hydroxyellipticine inhibits telomerase activity in human pancreatic cancer cells. |
| Q29301431 | A highly selective telomerase inhibitor limiting human cancer cell proliferation |
| Q64073887 | A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity |
| Q34414940 | A small molecule inhibitor of Pot1 binding to telomeric DNA. |
| Q36210474 | AZT as a telomerase inhibitor |
| Q39233356 | AZT on telomerase activity and cell proliferation in HS 839.T melanoma cells |
| Q34089694 | Aging and HIV/AIDS: pathogenetic role of therapeutic side effects |
| Q34114656 | Alternative lengthening of telomeres in mammalian cells |
| Q34519467 | Antiretroviral drug toxicity -- a challenge for the hepatologist? |
| Q40272786 | Assembly of mutant-template telomerase RNA into catalytically active telomerase ribonucleoprotein that can act on telomeres is required for apoptosis and cell cycle arrest in human cancer cells |
| Q33965940 | Attachment of HeT-A sequences to chromosomal termini in Drosophila melanogaster may occur by different mechanisms |
| Q40846967 | Attenuation of telomerase activity does not increase sensitivity of human melanoma cells to anticancer agents |
| Q45300431 | Azidothymidine induces apoptosis and inhibits cell growth and telomerase activity of human parathyroid cancer cells in culture. |
| Q40157259 | Biochemical properties of Trypanosoma cruzi telomerase |
| Q46140748 | Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase |
| Q40435095 | Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA. |
| Q34605651 | Chromosome break-induced DNA replication leads to nonreciprocal translocations and telomere capture. |
| Q36571591 | Chromosome end elongation by recombination in the mosquito Anopheles gambiae |
| Q43549618 | Chronic in vitro exposure to 3'-azido-2', 3'-dideoxythymidine induces senescence and apoptosis and reduces tumorigenicity of metastatic mouse mammary tumor cells |
| Q77337873 | Clinical evaluation of biologically targeted drugs: obstacles and opportunities |
| Q34249547 | Conversion of normal to malignant phenotype: telomere shortening, telomerase activation, and genomic instability during immortalization of human oral keratinocytes |
| Q33945457 | DNA G-quadruplexes, telomere-specific proteins and telomere-associated enzymes as potential targets for new anticancer drugs |
| Q40651914 | Delivering antisense telomerase RNA by a hybrid adenovirus/ adeno-associated virus significantly suppresses the malignant phenotype and enhances cell apoptosis of human breast cancer cells |
| Q41552071 | Development of a monoclonal antibody specific to the endonuclease domain of the human LINE-1 ORF2 protein |
| Q27026235 | Disruptive chemicals, senescence and immortality |
| Q52652673 | Down regulation of human telomerase reverse transcriptase (hTERT) expression by BIBR1532 in human glioblastoma LN18 cells. |
| Q34614236 | Dynamics of telomeric DNA turnover in yeast |
| Q38245881 | Epstein-Barr virus-encoded EBNA1 and ZEBRA: targets for therapeutic strategies against EBV-carrying cancers |
| Q42120610 | Expression of telomerase activity and oxidative stress in human hepatocellular carcinoma with cirrhosis |
| Q38310983 | Fibroblast growth factor 2 up regulates telomerase activity in neural precursor cells |
| Q38890930 | Friend or foe? Telomerase as a pharmacological target in cancer and cardiovascular disease |
| Q36139982 | HIV Infection Is Associated with Shortened Telomere Length in Ugandans with Suspected Tuberculosis |
| Q34150710 | HIV Infection, Inflammation, Immunosenescence, and Aging |
| Q34183753 | Homologous recombination as a mechanism of carcinogenesis |
| Q30771484 | Identification of a quinoxaline derivative that is a potent telomerase inhibitor leading to cellular senescence of human cancer cells |
| Q28291729 | Immortality of cell lines: challenges and advantages of establishment |
| Q39170367 | Immunosenescence and hurdles in the clinical management of older HIV-patients |
| Q28391094 | In vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIs |
| Q39572388 | In vitro expansion of mammalian telomere repeats by DNA polymerase alpha-primase |
| Q40970036 | Induction of telomerase activity in v-myc-transformed avian cells |
| Q37020676 | Inhibition of hTERT Gene Expression by Silibinin-Loaded PLGA-PEG-Fe3O4 in T47D Breast Cancer Cell Line |
| Q43153047 | Inhibition of human telomerase by a retrovirus expressing telomeric antisense RNA. |
| Q36742412 | Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death |
| Q73112617 | Inhibition of telomerase activity and cell proliferation by a reverse transcriptase inhibitor in gynaecological cancer cell lines |
| Q40711089 | Inhibition of telomerase activity by a distamycin derivative: effects on cell proliferation and induction of apoptosis in human cancer cells |
| Q73634097 | Inhibition of telomerase activity by cisplatin in human testicular cancer cells |
| Q45353122 | Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging |
| Q43831688 | Inhibition of telomerase activity in endometrial cancer cells by selenium-cisplatin conjugate despite suppression of its DNA-damaging activity by sodium ascorbate |
| Q42157485 | Inhibition of telomerase by linear-chain fatty acids: a structural analysis. |
| Q52536487 | Inhibition of telomerase limits the growth of human cancer cells. |
| Q34344690 | Leukocyte telomere length in HIV-infected and HIV-exposed uninfected children: shorter telomeres with uncontrolled HIV viremia |
| Q41121125 | Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening |
| Q81348475 | Low- to high-throughput analysis of telomerase modulators with Telospot |
| Q38291849 | Mechanism of human telomerase inhibition by BIBR1532, a synthetic, non-nucleosidic drug candidate. |
| Q41441652 | Mechanisms of cellular senescence |
| Q36361723 | Mechanisms of genotoxicity of nucleoside reverse transcriptase inhibitors |
| Q100750139 | Mechanisms of telomerase inhibition by oxidized and therapeutic dNTPs |
| Q48220061 | Molecular cloning of the canine telomerase reverse transcriptase gene and its expression in neoplastic and non-neoplastic cells |
| Q35122647 | Molecular interactions of ‘high risk’ human papillomaviruses E6 and E7 oncoproteins: implications for tumour progression |
| Q41583655 | Multiple pathways for the regulation of telomerase activity |
| Q24682080 | Mutations in the SBDS gene in acquired aplastic anemia |
| Q28505489 | Myc activates telomerase |
| Q31038583 | Natural and pharmacological regulation of telomerase |
| Q38875386 | New prospects for targeting telomerase beyond the telomere. |
| Q47878463 | Non-radioactive semiquantitative testing for the expression levels of telomerase activity in head and neck squamous cell carcinomas may be indicative for biological tumour behaviour |
| Q43844202 | Non-steroidal anti-inflammatory drugs inhibit telomerase activity in head and neck squamous carcinoma cell lines |
| Q37398211 | Pancreatic cancer stem cells: fact or fiction? |
| Q35849897 | Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence |
| Q34871781 | Pharmacodynamics of telomerase inhibition and telomere shortening by noncytotoxic suramin |
| Q35012107 | Pharmacological and biological aspects of basic research on nucleoside-based reverse transcriptase inhibitors |
| Q34970322 | Phenyl 1,2,3-triazole-thymidine ligands stabilize G-quadruplex DNA, inhibit DNA synthesis and potentially reduce tumor cell proliferation over 3'-azido deoxythymidine |
| Q27974791 | Plasmodium falciparum telomerase: de novo telomere addition to telomeric and nontelomeric sequences and role in chromosome healing |
| Q31138239 | Potent Inhibition of Human Telomerase by Nitrostyrene Derivatives |
| Q41679419 | Preclinical and clinical strategies for development of telomerase and telomere inhibitors |
| Q43967320 | Proliferation and telomere length in acutely mobilized blood mononuclear cells in HIV infected patients |
| Q34099669 | RAD50 function is essential for telomere maintenance in Arabidopsis. |
| Q42151209 | Regulation studies of telomerase gene in cancer cells by lentinan. |
| Q36748898 | Relevance of experimental models for investigation of genotoxicity induced by antiretroviral therapy during human pregnancy |
| Q36573452 | Reprogramming of telomerase by expression of mutant telomerase RNA template in human cells leads to altered telomeres that correlate with reduced cell viability |
| Q33653970 | Role of telomerase in cellular proliferation and cancer |
| Q38994464 | Selective protection of zidovudine-induced DNA-damage by the antioxidants WR-1065 and tempol. |
| Q46977865 | Small molecule, oligonucleotide-based telomerase template inhibition in combination with cytolytic therapy in an in vitro androgen-independent prostate cancer model |
| Q92495595 | Stilbene Compounds Inhibit Tumor Growth by the Induction of Cellular Senescence and the Inhibition of Telomerase Activity |
| Q29615653 | Switching and signaling at the telomere |
| Q40572704 | Synergy between 3'-azido-3'-deoxythymidine and paclitaxel in human pharynx FaDu cells |
| Q33383955 | Targeting human telomerase for cancer therapeutics. |
| Q37750789 | Targeting telomerase in hematologic malignancy |
| Q34330916 | Targeting telomeres and telomerase |
| Q40628938 | Telomerase Inhibition Using Azidothymidine in the HT-29 Colon Cancer Cell Line |
| Q38466711 | Telomerase RNA expression during progression of gastric cancer |
| Q74081673 | Telomerase activity in B-cell non-Hodgkin lymphoma |
| Q37228273 | Telomerase activity in gestational trophoblastic disease |
| Q40915656 | Telomerase activity in hybrids between telomerase-negative and telomerase-positive immortal human cells is repressed in the different complementation groups but not in the same complementation group of immortality |
| Q40828591 | Telomerase activity of cultured human pancreatic carcinoma cell lines correlates with their potential for migration and invasion |
| Q36171337 | Telomerase and its potential for therapeutic intervention |
| Q34241488 | Telomerase and oral cancer |
| Q37859251 | Telomerase and the endocrine system |
| Q28079188 | Telomerase as a Cancer Target. Development of New Molecules |
| Q34734539 | Telomerase as a diagnostic and therapeutic target for cancer |
| Q35597618 | Telomerase as a novel and potentially selective target for cancer chemotherapy |
| Q34535709 | Telomerase as a therapeutic target for malignant gliomas. |
| Q34398134 | Telomerase in endocrine and endocrine-dependent tumors |
| Q36446731 | Telomerase in kinetoplastid parasitic protozoa |
| Q34198649 | Telomerase inhibition as cancer therapy. |
| Q28292633 | Telomerase inhibition targets clonogenic multiple myeloma cells through telomere length-dependent and independent mechanisms |
| Q34141402 | Telomerase inhibitors |
| Q37101140 | Telomerase regulation of myofibroblast differentiation. |
| Q34148457 | Telomerase, immortality and cancer |
| Q33833328 | Telomerase. A target for anticancer therapy |
| Q34979724 | Telomerase: a target for cancer therapeutics |
| Q41239266 | Telomerase: anti-cancer target or just a fascinating enzyme? |
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| Q41035726 | Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase |
| Q40922360 | Telomere instability in a human cancer cell line |
| Q40777662 | Telomere length and telomerase activity in malignant lymphomas at diagnosis and relapse |
| Q54766150 | Telomere length variation and maintenance in hepatocarcinogenesis. |
| Q35800682 | Telomere maintenance in childhood primitive neuroectodermal brain tumors |
| Q40705259 | Telomere maintenance in telomerase-positive human ovarian SKOV-3 cells cannot be retarded by complete inhibition of telomerase |
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| Q57040833 | Telomere shortening in breast cancer cells (MCF7) under treatment with low doses of the benzylisoquinoline alkaloid chelidonine |
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| Q39392359 | The combined use of known antiviral reverse transcriptase inhibitors AZT and DDI induce anticancer effects at low concentrations. |
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