Telomere shortening in breast cancer cells (MCF7) under treatment with low doses of the benzylisoquinoline alkaloid chelidonine

scientific article published in PLoS ONE

Telomere shortening in breast cancer cells (MCF7) under treatment with low doses of the benzylisoquinoline alkaloid chelidonine is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1371/JOURNAL.PONE.0204901
P932PMC publication ID6169906
P698PubMed publication ID30281650

P50authorSakineh Kazemi NoureiniQ56544559
P2093author name stringMichael Wink
Leili Fatemi
P2860cites workBreast cancer survival is associated with telomere length in peripheral blood cellsQ51702224
Chelidonine isolated from ethanolic extract of Chelidonium majus promotes apoptosis in HeLa cells through p38-p53 and PI3K/AKT signalling pathways.Q53145282
Telomere length dynamics in telomerase-positive immortal human cell populationsQ53435983
Real-time quantitative telomeric repeat amplification protocol assay for the detection of telomerase activityQ73586375
Tissue-specific alternate splicing of human telomerase reverse transcriptase (hTERT) influences telomere lengths during human developmentQ73670399
Telomere length measurement by a novel monochrome multiplex quantitative PCR methodQ37108473
Telomere and telomerase as targets for cancer therapyQ37468610
Telomerase: Structure, functions, and activity regulationQ37854760
Telomerase as a "stemness" enzymeQ38211826
Selectivity of major isoquinoline alkaloids from Chelidonium majus towards telomeric G-quadruplex: A study using a transition-FRET (t-FRET) assayQ38288204
The Interference of Selected Cytotoxic Alkaloids with the Cytoskeleton: An Insight into Their Modes of ActionQ38758021
Structure and function of telomeresQ38763424
Telomerase and telomere biology in hematological diseases: A new therapeutic targetQ39135191
Transcriptional down regulation of hTERT and senescence induction in HepG2 cells by chelidonineQ39816965
Differential effect of sanguinarine, chelerythrine and chelidonine on DNA damage and cell viability in primary mouse spleen cells and mouse leukemic cellsQ40047153
Pharmacodynamics of the G-quadruplex-stabilizing telomerase inhibitor 3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in vitro: activity in human tumor cells correlates with telomere length and can be enhanced, or anQ40375807
Pharmacological telomerase inhibition can sensitize drug-resistant and drug-sensitive cells to chemotherapeutic treatmentQ40412924
Telomere structure and functionQ40428297
An alternate splicing variant of the human telomerase catalytic subunit inhibits telomerase activityQ40825989
Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcriptsQ41006486
Structure and function of telomeraseQ41066960
Pharmacological activities of Chelidonium majus L. (Papaveraceae).Q41164899
Larvicidal activity and insecticidal mechanism of Chelidonium majus on Lymantria disparQ50138569
hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during ImmortalizationQ24310670
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assaysQ25939005
Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapiesQ26744271
Telomere length regulationQ28290143
Dynamics of protein binding to telomeres in living cells: implications for telomere structure and functionQ30762674
Selective inhibition of in vitro cell growth by the anti-tumour drug UkrainQ31158943
The effects of chelidonine on tubulin polymerisation, cell cycle progression and selected signal transmission pathwaysQ32043480
Quantitative theory of telomere length regulation and cellular senescenceQ33777886
Alternative splicing regulation of telomerase: a new paradigm?Q34310398
Telomerase regulation: not just flipping the switchQ34493169
Longer Telomere Length in Peripheral White Blood Cells Is Associated with Risk of Lung Cancer and the rs2736100 (CLPTM1L-TERT) Polymorphism in a Prospective Cohort Study among Women in ChinaQ34650906
Telomere maintenance and cancer -- look, no telomerase.Q34988280
Chelidonium majus is not hepatotoxic in Wistar rats, in a 4 weeks feeding experimentQ35003665
High-mobility group A2 protein modulates hTERT transcription to promote tumorigenesis.Q35096589
Telomerase expression and telomere length in breast cancer and their associations with adjuvant treatment and disease outcomeQ35558080
Telomeres: cancer to human agingQ36528826
Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell linesQ36556649
Association of leukocyte telomere length with breast cancer risk: nested case-control findings from the Shanghai Women's Health StudyQ36854065
Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.Q36885740
Role of telomeres and telomerase in genomic instability, senescence and cancerQ36927502
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)e0204901
P577publication date2018-10-03
P1433published inPLOS OneQ564954
P1476titleTelomere shortening in breast cancer cells (MCF7) under treatment with low doses of the benzylisoquinoline alkaloid chelidonine
P478volume13

Reverse relations

Q89976569Effective Inhibition of Candidiasis Using an Eco-Friendly Leaf Extract of Calotropis-gigantean-Mediated Silver Nanoparticlescites workP2860

Search more.