| review article | Q7318358 |
| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1024134431 |
| P356 | DOI | 10.1038/SJ.ONC.1205058 |
| P698 | PubMed publication ID | 11850785 |
| P5875 | ResearchGate publication ID | 11510241 |
| P50 | author | Roger Reddel | Q55948927 |
| P2093 | author name string | Axel A Neumann | |
| Thomas R Yeager | |||
| Jeremy D Henson | |||
| P2860 | cites work | Mammalian telomeres end in a large duplex loop | Q22009893 |
| Normal human chromosomes have long G-rich telomeric overhangs at one end | Q22065787 | ||
| Nuclear structure in normal and Bloom syndrome cells | Q22253976 | ||
| Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres | Q22254585 | ||
| Regulation and localization of the Bloom syndrome protein in response to DNA damage | Q24291133 | ||
| Telomeric protein Pin2/TRF1 induces mitotic entry and apoptosis in cells with short telomeres and is down-regulated in human breast tumors | Q24291157 | ||
| p53 Modulates the exonuclease activity of Werner syndrome protein | Q24291371 | ||
| Interaction of p53 with the human Rad51 protein | Q24309466 | ||
| Telomere elongation in immortal human cells without detectable telomerase activity | Q24598626 | ||
| Chromosome 7 suppresses indefinite division of nontumorigenic immortalized human fibroblast cell lines KMST-6 and SUSM-1 | Q24629799 | ||
| Human telomeres contain at least three types of G-rich repeat distributed non-randomly | Q24635832 | ||
| A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae. | Q27932204 | ||
| Recombination-mediated lengthening of terminal telomeric repeats requires the Sgs1 DNA helicase | Q27933140 | ||
| Accelerated telomere shortening in ataxia telangiectasia | Q57017468 | ||
| Telomerase Activity in Benign and Malignant Thyroid Tumors | Q59592127 | ||
| SGS1 is required for telomere elongation in the absence of telomerase | Q61782242 | ||
| Evidence for the recessive nature of cellular immortality | Q71810575 | ||
| DNA structure-dependent requirements for yeast RAD genes in gene conversion | Q72356626 | ||
| Telomerase-independent lengthening of yeast telomeres occurs by an abrupt Rad50p-dependent, Rif-inhibited recombinational process | Q73221736 | ||
| Telomerase activity in thyroid malignancy | Q73383331 | ||
| Chondrosarcoma is not characterized by detectable telomerase activity | Q73592730 | ||
| Accumulation of short telomeres in human fibroblasts prior to replicative senescence | Q73598455 | ||
| Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines | Q73851376 | ||
| Telomerase activity in human thyroid carcinomas originating from the follicular cells | Q73941318 | ||
| Telomerase activity and telomere length in thyroid neoplasia: biological and clinical implications | Q74002682 | ||
| Telomerase activity in the differential diagnosis of papillary carcinoma of the thyroid | Q74028985 | ||
| Alternative lengthening of telomeres is associated with chromosomal instability in osteosarcomas | Q74141706 | ||
| A repressor function for telomerase activity in telomerase-negative immortal cells | Q74214904 | ||
| Telomeric lengths and telomerase activity in liposarcomas | Q74608451 | ||
| Telomeric interactions result in the formation of intramolecular circles behaving as topologically constrained | Q77373679 | ||
| UBL1, a human ubiquitin-like protein associating with human RAD51/RAD52 proteins | Q28115876 | ||
| NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres | Q28141883 | ||
| The transcriptional role of PML and the nuclear body | Q28144176 | ||
| Pot1, the putative telomere end-binding protein in fission yeast and humans | Q28188476 | ||
| Functional interaction of p53 and BLM DNA helicase in apoptosis | Q28201136 | ||
| Evidence for BLM and Topoisomerase IIIalpha interaction in genomic stability | Q28201848 | ||
| Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51 | Q28207894 | ||
| Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism | Q28245231 | ||
| Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation | Q28367104 | ||
| Homologous recombinational repair of DNA ensures mammalian chromosome stability | Q28646561 | ||
| A survey of telomerase activity in human cancer | Q29614858 | ||
| An alternative pathway for yeast telomere maintenance rescues est1- senescence | Q29616135 | ||
| Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells | Q29617437 | ||
| Extrachromosomal rDNA circles--a cause of aging in yeast | Q29618308 | ||
| Transitions in distinct histone H3 methylation patterns at the heterochromatin domain boundaries | Q29622865 | ||
| Characterization of genetic interactions with RFA1: the role of RPA in DNA replication and telomere maintenance. | Q30846929 | ||
| Telomere maintenance mechanisms and cellular immortalization. | Q33540084 | ||
| Reconsideration of senescence, immortalization and telomere maintenance of Epstein-Barr virus-transformed human B-lymphoblastoid cell lines | Q33591008 | ||
| Genetic analysis of indefinite division in human cells: identification of four complementation groups | Q33640611 | ||
| Extragenomic double-stranded DNA circles in yeast with linear mitochondrial genomes: potential involvement in telomere maintenance. | Q33834202 | ||
| RecQ family helicases: roles in cancer and aging | Q33840427 | ||
| The role of senescence and immortalization in carcinogenesis | Q33846221 | ||
| Recombination-dependent DNA replication in phage T4. | Q33885411 | ||
| Ubiquitin-like proteins: new wines in new bottles | Q33901542 | ||
| Review: properties and assembly mechanisms of ND10, PML bodies, or PODs | Q33915723 | ||
| Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae | Q33958350 | ||
| Telomere maintenance in telomerase-deficient mouse embryonic stem cells: characterization of an amplified telomeric DNA | Q33963894 | ||
| Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells | Q33968413 | ||
| DNA strand break-sensing molecule poly(ADP-Ribose) polymerase cooperates with p53 in telomere function, chromosome stability, and tumor suppression | Q33968476 | ||
| Intrachromatid excision of telomeric DNA as a mechanism for telomere size control in Saccharomyces cerevisiae | Q34012288 | ||
| Alternative lengthening of telomeres in human cells | Q34106258 | ||
| Telomeric chromatin: replicating and wrapping up chromosome ends. | Q34183869 | ||
| t-loops at trypanosome telomeres. | Q34271330 | ||
| Linear mitochondrial genomes: 30 years down the line | Q34470399 | ||
| Cyclin D1 overexpression and p53 inactivation immortalize primary oral keratinocytes by a telomerase-independent mechanism | Q36167748 | ||
| In situ analysis of changes in telomere size during replicative aging and cell transformation | Q36237144 | ||
| Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice | Q36255827 | ||
| Telomerase activity in benign and malignant human thyroid tissues | Q36292966 | ||
| Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts | Q36554262 | ||
| Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines | Q36556649 | ||
| Spontaneous in vitro immortalization of breast epithelial cells from a patient with Li-Fraumeni syndrome | Q36567058 | ||
| Chromosome end elongation by recombination in the mosquito Anopheles gambiae | Q36571591 | ||
| Unusual chromatin in human telomeres | Q36664811 | ||
| Telomeres of polytene chromosomes in a ciliated protozoan terminate in duplex DNA loops | Q36745869 | ||
| Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types. | Q36885740 | ||
| Extra-chromosomal telomere repeat DNA in telomerase-negative immortalized cell lines | Q38335980 | ||
| Extended lifespan and immortalization of human fibroblasts induced by X-ray irradiation | Q38505755 | ||
| Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae | Q39449233 | ||
| Characterization of a fission yeast SUMO-1 homologue, pmt3p, required for multiple nuclear events, including the control of telomere length and chromosome segregation | Q39449792 | ||
| The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase | Q39714537 | ||
| Impaired germinal center reaction in mice with short telomeres. | Q40387000 | ||
| Effects of reconstitution of telomerase activity on telomere maintenance by the alternative lengthening of telomeres (ALT) pathway | Q40780747 | ||
| Telomere maintenance by telomerase and by recombination can coexist in human cells | Q40780754 | ||
| Telomerase can inhibit the recombination-based pathway of telomere maintenance in human cells | Q40800667 | ||
| Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability | Q40810954 | ||
| Coordinated response of mammalian Rad51 and Rad52 to DNA damage | Q40820236 | ||
| Telomere maintenance by recombination in human cells. | Q40839283 | ||
| TRF1 is a critical trans-acting factor required for de novo telomere formation in human cells | Q40844299 | ||
| Telomerase activation in human fibroblasts during escape from crisis | Q40948903 | ||
| Repression of an alternative mechanism for lengthening of telomeres in somatic cell hybrids | Q40949588 | ||
| Telomeric repeats on small polydisperse circular DNA (spcDNA) and genomic instability | Q40971278 | ||
| Telomerase activity during spontaneous immortalization of Li-Fraumeni syndrome skin fibroblasts | Q41014086 | ||
| Release of telomeric DNA from chromosomes in immortal human cells lacking telomerase activity | Q41022922 | ||
| Reconstitution of wild-type or mutant telomerase activity in telomerase-negative immortal human cells | Q41036325 | ||
| Normal telomere maintenance in immortal ataxia telangiectasia cell lines | Q41081333 | ||
| Decrease in amplified telomeric sequences and induction of senescence markers by introduction of human chromosome 7 or its segments in SUSM-1. | Q41090781 | ||
| The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit | Q41108271 | ||
| Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein | Q41121233 | ||
| Small polydispersed circular DNA (spcDNA) in human cells: association with genomic instability | Q41126653 | ||
| Reduced telomere length in ataxia-telangiectasia fibroblasts | Q41169096 | ||
| Telomere elongation observed in immortalized human fibroblasts by treatment with 60Co gamma rays or 4-nitroquinoline 1-oxide | Q41255624 | ||
| Aflatoxin B1-induced immortalization of cultured skin fibroblasts from a patient with Li-Fraumeni syndrome. | Q41390877 | ||
| Genetic complementation of the immortal phenotype in group D cell lines by introduction of chromosome 7. | Q41394955 | ||
| Telomere dynamics and telomerase activity in in vitro immortalised human cells. | Q41583660 | ||
| Telomerase activity in benign and malignant thyroid diseases | Q41679453 | ||
| Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex | Q41774217 | ||
| Structure, organization, and dynamics of promyelocytic leukemia protein nuclear bodies. | Q41840026 | ||
| Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase | Q46140748 | ||
| Addition of telomere-associated HeT DNA sequences "heals" broken chromosome ends in Drosophila | Q46354229 | ||
| A novel mechanism for telomere size control in Saccharomyces cerevisiae | Q47331172 | ||
| Defects in mismatch repair promote telomerase-independent proliferation | Q48361396 | ||
| Telomere length dynamics in telomerase-positive immortal human cell populations. | Q53435983 | ||
| Significant correlation of telomerase activity in thyroid papillary carcinomas with cell differentiation, proliferation and extrathyroidal extension. | Q55376947 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 598-610 | |
| P577 | publication date | 2002-01-01 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | Alternative lengthening of telomeres in mammalian cells | |
| P478 | volume | 21 |
| Q79862705 | A common means to an end |
| Q39811985 | A gene expression signature classifying telomerase and ALT immortalization reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT. |
| Q53150031 | A high rate of telomeric sister chromatid exchange occurs in chronic lymphocytic leukaemia B-cells. |
| Q40382157 | A human cell line that maintains telomeres in the absence of telomerase and of key markers of ALT. |
| Q48343771 | A method for measuring the distribution of the shortest telomeres in cells and tissues |
| Q34042826 | A mutation in the STN1 gene triggers an alternative lengthening of telomere-like runaway recombinational telomere elongation and rapid deletion in yeast |
| Q39897904 | A role for monoubiquitinated FANCD2 at telomeres in ALT cells |
| Q63384201 | A role for the Rb family of proteins in controlling telomere length |
| Q89509813 | ALT: A Multi-Faceted Phenomenon |
| Q41844732 | ALTernative Telomere Maintenance and Cancer. |
| Q36156849 | ATM regulates the length of individual telomere tracts in Arabidopsis |
| Q36140856 | ATRX represses alternative lengthening of telomeres |
| Q33927486 | Abrupt disruption of capping and a single source for recombinationally elongated telomeres in Kluyveromyces lactis |
| Q36492022 | Aging and immortality in a cell proliferation model |
| Q47552952 | Alpha Thalassemia/Mental Retardation Syndrome X-Linked, the Alternative Lengthening of Telomere Phenotype, and Gliomagenesis: Current Understandings and Future Potential |
| Q91964463 | Alternative Lengthening of Telomeres (ALT) in Tumors and Pluripotent Stem Cells |
| Q89622479 | Alternative Lengthening of Telomeres in Pediatric Cancer: Mechanisms to Therapies |
| Q89893294 | Alternative Lengthening of Telomeres: Building Bridges To Connect Chromosome Ends |
| Q64091975 | Alternative lengthening of telomeres (ALT) influences survival in soft tissue sarcomas: a systematic review with meta-analysis |
| Q38999039 | Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations |
| Q35131772 | Alternative lengthening of telomeres, telomerase, and cancer. |
| Q33966399 | Alternative lengthening of telomeres: dangerous road less travelled |
| Q34107386 | Alternative lengthening of telomeres: models, mechanisms and implications |
| Q37382517 | Alternative lengthening of telomeres: recurrent cytogenetic aberrations and chromosome stability under extreme telomere dysfunction. |
| Q38083475 | Alternative lengthening of telomeres: remodeling the telomere architecture |
| Q33900715 | An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres |
| Q34419568 | An integrated overview of spatiotemporal organization and regulation in mitosis in terms of the proteins in the functional supercomplexes. |
| Q45166425 | Analysis of BAC clones containing homologous sequences on the end of the Xq arm and on chromosome 7 in the dioecious plant Silene latifolia. |
| Q37420553 | Analysis of alternative lengthening of telomere markers in BRCA1 defective cells |
| Q33450956 | Apoptosis and telomeres shortening related to HIV-1 induced oxidative stress in an astrocytoma cell line |
| Q40453428 | Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands. |
| Q37764530 | Assaying and investigating Alternative Lengthening of Telomeres activity in human cells and cancers. |
| Q35050968 | Assessment of telomere length and factors that contribute to its stability |
| Q28115349 | BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping |
| Q38914174 | Biosafety evidence for human dedifferentiated adipocytes |
| Q34037586 | Break-induced DNA replication |
| Q42039020 | Break-induced replication and genome stability. |
| Q27933035 | Break-induced replication and telomerase-independent telomere maintenance require Pol32. |
| Q35974184 | Caenorhabditis elegans POT-2 telomere protein represses a mode of alternative lengthening of telomeres with normal telomere lengths |
| Q91272447 | Cancer therapy with a CRISPR-assisted telomerase-activating gene expression system |
| Q36851568 | Cellular lifespan and regenerative medicine |
| Q39707900 | Characterization of human multicentric osteosarcoma using newly established cells derived from multicentric osteosarcoma |
| Q54959206 | Chemotherapeutic-Induced Cardiovascular Dysfunction: Physiological Effects, Early Detection-The Role of Telomerase to Counteract Mitochondrial Defects and Oxidative Stress. |
| Q33926851 | Chk2 and p53 are haploinsufficient with dependent and independent functions to eliminate cells after telomere loss |
| Q38456436 | Chromosome aberrations and telomere length modulation in bone marrow and spleen cells of melphalan-treated p53+/- mice. |
| Q35201471 | Chromosome aberrations in solid tumors |
| Q34604643 | Combination of telomerase antisense oligonucleotides simultaneously targeting hTR and hTERT produces synergism of inhibition of telomerase activity and growth in human colon cancer cell line |
| Q58134264 | Comparison of mesenchymal stem cells isolated from various tissues of isogenic mini-pig |
| Q37404058 | Computational selection and experimental validation of allosteric ribozymes that sense a specific sequence of human telomerase reverse transcriptase mRNAs as universal anticancer therapy agents |
| Q39238726 | Construction of a novel vector expressing the fusion suicide gene yCDglyTK and hTERT-shRNA and its antitumor effects |
| Q36186824 | Construction of synthetic nucleoli and what it tells us about propagation of sub-nuclear domains through cell division. |
| Q48023136 | Current Perspectives of Telomerase Structure and Function in Eukaryotes with Emerging Views on Telomerase in Human Parasites |
| Q40883583 | Degradation of p53, not telomerase activation, by E6 is required for bypass of crisis and immortalization by human papillomavirus type 16 E6/E7. |
| Q35052082 | Depletion of Ku70/80 reduces the levels of extrachromosomal telomeric circles and inhibits proliferation of ALT cells |
| Q39801213 | Detection of Meningeosis neoplastica by real-time quantitation of telomerase activity |
| Q36559242 | Detection of alternative lengthening of telomeres by telomere quantitative PCR. |
| Q39898215 | Detection of circular telomeric DNA without 2D gel electrophoresis |
| Q41309055 | Different effects of accelerated development and enhanced growth on oxidative stress and telomere shortening in amphibian larvae. |
| Q36121451 | Different expression of alternative lengthening of telomere (ALT)-associated proteins/mRNAs in osteosarcoma cell lines |
| Q58270989 | Differentiation potential of mesenchymal stem cells isolated from human dental tissues into non-mesodermal lineage |
| Q40503154 | Distinct profiles of critically short telomeres are a key determinant of different chromosome aberrations in immortalized human cells: whole-genome evidence from multiple cell lines. |
| Q40529799 | Divergent patterns of telomere maintenance mechanisms among human sarcomas: sharply contrasting prevalence of the alternative lengthening of telomeres mechanism in Ewing's sarcomas and osteosarcomas |
| Q42426732 | EXO1 plays a role in generating type I and type II survivors in budding yeast |
| Q24811173 | Efficient isothermal expansion of human telomeric and minisatellite repeats by Thermococcus litoralis DNA polymerase |
| Q33275302 | Elevated rates of sister chromatid exchange at chromosome ends |
| Q37961786 | Epigenetic regulation of telomere chromatin integrity in pluripotent embryonic stem cells |
| Q40643001 | Equine telomeres and telomerase in cellular immortalisation and ageing |
| Q89967646 | Expression of tert Prevents ALT in Zebrafish Brain Tumors |
| Q38517737 | Expression profiling identifies three pathways altered in cellular immortalization: interferon, cell cycle, and cytoskeleton. |
| Q33859427 | Extrachromosomal telomeric circles contribute to Rad52-, Rad50-, and polymerase delta-mediated telomere-telomere recombination in Saccharomyces cerevisiae. |
| Q42548726 | Fanconi anemia proteins and endogenous stresses |
| Q36247908 | Fission yeast Rhp51 is required for the maintenance of telomere structure in the absence of the Ku heterodimer |
| Q38536371 | Forging a signature of in vivo senescence |
| Q36827578 | Frequent recombination in telomeric DNA may extend the proliferative life of telomerase-negative cells |
| Q37624069 | Frequent somatic mutations of the telomerase reverse transcriptase promoter in ovarian clear cell carcinoma but not in other major types of gynaecological malignancy. |
| Q38890930 | Friend or foe? Telomerase as a pharmacological target in cancer and cardiovascular disease |
| Q36232699 | Functional interaction between poly(ADP-Ribose) polymerase 2 (PARP-2) and TRF2: PARP activity negatively regulates TRF2. |
| Q35853775 | Functional links between telomeres and proteins of the DNA-damage response |
| Q35153446 | G-quadruplex formation at the 3' end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase |
| Q42576862 | G-quadruplex preferentially forms at the very 3' end of vertebrate telomeric DNA |
| Q38154988 | G-quadruplexes as potential therapeutic targets for embryonal tumors |
| Q28118811 | GNL3L stabilizes the TRF1 complex and promotes mitotic transition |
| Q34514751 | Gene expression levels of human shelterin complex and shelterin-associated factors regulated by the topoisomerase II inhibitors doxorubicin and etoposide in human cultured cells |
| Q35011348 | Genetic variation exists for telomeric array organization within and among the genomes of normal, immortalized, and transformed chicken systems |
| Q37675160 | Genistein suppresses the proliferation of telomerase-negative cells |
| Q40975957 | Genome-wide analysis to identify pathways affecting telomere-initiated senescence in budding yeast. |
| Q34612265 | Genomic instability and cancer: Lessons learned from human papillomaviruses |
| Q34549397 | Genomic instability in both wild-type and telomerase null MEFs |
| Q34073316 | G‐quadruplex nucleic acids and human disease |
| Q33828273 | HP1-mediated formation of alternative lengthening of telomeres-associated PML bodies requires HIRA but not ASF1a |
| Q39910328 | HPV-16 E7 reveals a link between DNA replication stress, fanconi anemia D2 protein, and alternative lengthening of telomere-associated promyelocytic leukemia bodies |
| Q36615652 | High level of telomerase RNA gene expression is associated with chromatin modification, the ALT phenotype and poor prognosis in liposarcoma |
| Q39030767 | Histone methylation controls telomerase-independent telomere lengthening in cells undergoing dedifferentiation. |
| Q64387070 | Homolog Dependent Repair Following Dicentric Chromosome Breakage in |
| Q34250567 | Homologous recombination in human telomerase‐positive and ALT cells occurs with the same frequency |
| Q28188135 | Human CLK2 links cell cycle progression, apoptosis, and telomere length regulation |
| Q33635574 | Human RECQL1 participates in telomere maintenance |
| Q24562757 | Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint |
| Q34625007 | Human mesenchymal stem cells from chorionic villi and amniotic fluid are not susceptible to transformation after extensive in vitro expansion |
| Q37810521 | Human telomerase activity regulation. |
| Q38323779 | Id2 protein is selectively upregulated by UVB in primary, but not in immortalized human keratinocytes and inhibits differentiation |
| Q64052888 | Identification of patient-derived glioblastoma stem cell (GSC) lines with the alternative lengthening of telomeres phenotype |
| Q40578218 | Immortalization in a normal foreskin fibroblast culture following transduction of cyclin A2 or cdk1 genes in retroviral vectors. |
| Q34117301 | Immortalization of oral keratinocytes by functional inactivation of the p53 and pRb pathways. |
| Q36255511 | Immortalized cells as experimental models to study cancer. |
| Q38862869 | Impaired telomerase activity hinders proliferation and in vitro transformation of Penaeus monodon lymphoid cells |
| Q28066490 | Implications of telomeres and telomerase in endometrial pathology |
| Q53364208 | Increased hTR expression during transition from adenoma to carcinoma is not associated with promoter methylation. |
| Q37264012 | Induction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins |
| Q35676717 | Ink4a/Arf tumor suppressor does not modulate the degenerative conditions or tumor spectrum of the telomerase-deficient mouse |
| Q39140555 | Inter-telomeric recombination is present in telomerase-positive human cells |
| Q51091931 | Introduction to Telomeres and Telomerase. |
| Q37908470 | Is telomerase a viable target in cancer? |
| Q54334207 | Keeping those telomeres short! an innovative intratumoral long-term drug delivery system. |
| Q92046278 | Long interspersed element-1 ribonucleoprotein particles protect telomeric ends in alternative lengthening of telomeres dependent cells |
| Q34469050 | Long telomeres produced by telomerase-resistant recombination are established from a single source and are subject to extreme sequence scrambling |
| Q40479113 | Long-term controlled immortalization of a primate hepatic progenitor cell line after Simian virus 40 T-Antigen gene transfer. |
| Q40578181 | Long-term molecular and cellular stability of human neural stem cell lines. |
| Q28115086 | Loss of ATRX Suppresses Resolution of Telomere Cohesion to Control Recombination in ALT Cancer Cells |
| Q34350929 | Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway |
| Q34490971 | Loss of wild-type ATRX expression in somatic cell hybrids segregates with activation of Alternative Lengthening of Telomeres |
| Q36210968 | Maintenance of very long telomeres by recombination in the Kluyveromyces lactis stn1-M1 mutant involves extreme telomeric turnover, telomeric circles, and concerted telomeric amplification |
| Q35569699 | Mammalian telomeres and telomerase: why they matter for cancer and aging |
| Q35125280 | Mapping and initial analysis of human subtelomeric sequence assemblies |
| Q38987554 | Means to the ends: The role of telomeres and telomere processing machinery in metastasis |
| Q34341678 | Measuring vertebrate telomeres: applications and limitations |
| Q34317108 | Mechanisms of double-strand break repair in somatic mammalian cells |
| Q33937189 | Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging |
| Q40407926 | Mitotic cyclins regulate telomeric recombination in telomerase-deficient yeast cells. |
| Q35875776 | Modulation of telomeres in alternative lengthening of telomeres type I like human cells by the expression of werner protein and telomerase |
| Q26860786 | Molecular characteristics of pediatric high-grade gliomas |
| Q30810861 | Mouse major satellite DNA is prone to eccDNA formation via DNA Ligase IV-dependent pathway. |
| Q34275159 | Multiple Mechanisms Contribute To Telomere Maintenance |
| Q35614009 | Need telomere maintenance? Call 911 |
| Q89581155 | Nuclear PARPs and genome integrity |
| Q37843627 | Nurturing the genome: A-type lamins preserve genomic stability |
| Q43800943 | On BLM helicase in recombination-mediated telomere maintenance |
| Q28544458 | Oxidative stress induces persistent telomeric DNA damage responsible for nuclear morphology change in mammalian cells |
| Q38008909 | PML body meets telomere: the beginning of an ALTernate ending? |
| Q91843058 | PML is recruited to heterochromatin during S phase and represses DAXX-mediated histone H3.3 chromatin assembly |
| Q45617415 | PML-nuclear bodies accumulate DNA in response to polyomavirus BK and simian virus 40 replication |
| Q24308828 | POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates |
| Q98289868 | POT1-TPP1 telomere length regulation and disease |
| Q97069904 | Persistent telomere cohesion protects aged cells from premature senescence |
| Q43036800 | Presence of alternative lengthening of telomeres mechanism in patients with glioblastoma identifies a less aggressive tumor type with longer survival. |
| Q37354145 | Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination |
| Q35130676 | Profiling breast cancer by array CGH. |
| Q81348453 | Profiling early head and neck cancer |
| Q34665512 | Prognostic significance of telomere maintenance mechanisms in pediatric high-grade gliomas |
| Q35172449 | Prolonged self-renewal activity unmasks telomerase control of telomere homeostasis and function of mouse hematopoietic stem cells |
| Q35914635 | Promyelocytic leukemia nuclear bodies support a late step in DNA double-strand break repair by homologous recombination |
| Q24315634 | Purification of proteins associated with specific genomic Loci |
| Q42259176 | Radiation-induced telomere length variations in normal and in Nijmegen Breakage Syndrome cells |
| Q34994566 | RecQ helicases and cellular responses to DNA damage |
| Q24675453 | Repairing a double-strand chromosome break by homologous recombination: revisiting Robin Holliday's model |
| Q35128142 | Replication fork regression in repetitive DNAs |
| Q24298583 | Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres |
| Q34139562 | Reprogramming of telomeric regions during the generation of human induced pluripotent stem cells and subsequent differentiation into fibroblast-like derivatives |
| Q35612349 | Role of SUMO in the dynamics of telomere maintenance in fission yeast |
| Q35169573 | Role of mammalian Rad54 in telomere length maintenance |
| Q40197403 | Role of the fission yeast SUMO E3 ligase Pli1p in centromere and telomere maintenance. |
| Q33649477 | SUMO Wrestles with Recombination |
| Q41789831 | Separating the effects of telomere size from the mechanism of telomere elongation |
| Q33694309 | Sex-related differences in length and erosion dynamics of human telomeres favor females |
| Q36803209 | Sp100A promotes chromatin decondensation at a cytomegalovirus-promoter-regulated transcription site |
| Q39771209 | Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions. |
| Q36249103 | Stable expression of promyelocytic leukaemia (PML) protein in telomerase positive MCF7 cells results in alternative lengthening of telomeres phenotype |
| Q94069607 | Structure of Dictyostelium discoideum telomeres. Analysis of possible replication mechanisms |
| Q33751911 | Subcellular distribution of nuclear import-defective isoforms of the promyelocytic leukemia protein |
| Q39878291 | Subtelomeric DNA hypomethylation is not required for telomeric sister chromatid exchanges in ALT cells. |
| Q27933175 | Sumoylation and the structural maintenance of chromosomes (Smc) 5/6 complex slow senescence through recombination intermediate resolution |
| Q35962436 | Swi1Timeless Prevents Repeat Instability at Fission Yeast Telomeres. |
| Q35741027 | T-loops and the origin of telomeres |
| Q39146154 | TERRA Expression Levels Do Not Correlate with Telomere Length and Radiation Sensitivity in Human Cancer Cell Lines |
| Q37614123 | Targeting homologous recombination and telomerase in Barrett's adenocarcinoma: impact on telomere maintenance, genomic instability and tumor growth |
| Q36017631 | Targeting telomerase-expressing cancer cells |
| Q37825614 | Targeting the telomere and shelterin complex for cancer therapy: current views and future perspectives. |
| Q58075081 | Telomerase Activity and Telomere Length in Primary and Metastatic Tumors from Pediatric Bone Cancer Patients |
| Q33967373 | Telomerase Cajal body protein 1 depletion inhibits telomerase trafficking to telomeres and induces G1 cell cycle arrest in A549 cells |
| Q34785598 | Telomerase RNA Accumulates in Cajal Bodies in Human Cancer Cells |
| Q36371899 | Telomerase activation and rejuvenation of telomere length in stimulated T cells derived from serially transplanted hematopoietic stem cells |
| Q54363087 | Telomerase activity analyzed with TRAP in situ provides additional information in effusions remaining equivocal after immunocytochemistry and hyaluronan analysis. |
| Q52829634 | Telomerase activity in cell lines of pediatric soft tissue sarcomas. |
| Q80126055 | Telomerase as a potential marker for early diagnosing cervical carcinoma |
| Q34188701 | Telomerase contributes to tumorigenesis by a telomere length-independent mechanism |
| Q34188137 | Telomerase extracurricular activities |
| Q36638624 | Telomerase inhibition in cancer therapeutics: molecular-based approaches |
| Q36854864 | Telomerase reverse transcriptase is required for the localization of telomerase RNA to cajal bodies and telomeres in human cancer cells |
| Q43179667 | Telomerase- and Rad52-independent immortalization of budding yeast by an inherited-long-telomere pathway of telomeric repeat amplification. |
| Q40294605 | Telomerase- and recombination-independent immortalization of budding yeast |
| Q34396480 | Telomerase-dependent and independent telomere maintenance and its clinical implications in medullary thyroid carcinoma |
| Q37982375 | Telomerase-independent paths to immortality in predictable cancer subtypes |
| Q34617934 | Telomerase-independent proliferation is influenced by cell type in Saccharomyces cerevisiae |
| Q41490785 | Telomerase-independent stabilization of short telomeres in Trypanosoma brucei |
| Q34979724 | Telomerase: a target for cancer therapeutics |
| Q61812921 | Telomere Biology and Human Phenotype |
| Q47265486 | Telomere Biology and Thoracic Aortic Aneurysm |
| Q48303727 | Telomere Homeostasis: Interplay with Magnesium. |
| Q50131917 | Telomere Length Dynamics and the Evolution of Cancer Genome Architecture |
| Q49803981 | Telomere Length Maintenance in Cancer: At the Crossroad between Telomerase and Alternative Lengthening of Telomeres (ALT). |
| Q36103191 | Telomere and telomerase as targets for anti-cancer and regeneration therapies |
| Q35692612 | Telomere biology of human hematopoietic stem cells |
| Q36103575 | Telomere biology: integrating chromosomal end protection with DNA damage response |
| Q34424261 | Telomere deficiencies on chromosomes 9p, 15p, 15q and Xp: potential biomarkers for breast cancer risk |
| Q48922014 | Telomere dysfunction and chromothripsis |
| Q38472856 | Telomere dysfunction drives chromosomal instability in human mammary epithelial cells. |
| Q61696490 | Telomere elongation during early development is independent of environmental temperatures in Atlantic salmon |
| Q34558645 | Telomere fusion to chromosome breaks reduces oncogenic translocations and tumour formation |
| Q48589695 | Telomere length and telomerase activity in bovine pre-implantation embryos in vitro |
| Q90689187 | Telomere length heterogeneity in ALT cells is maintained by PML-dependent localization of the BTR complex to telomeres |
| Q38174453 | Telomere length maintenance, shortening, and lengthening |
| Q42409482 | Telomere length reprogramming in embryos and stem cells |
| Q47691938 | Telomere length, ATM mutation status and cancer risk in Ataxia-Telangiectasia families |
| Q35098120 | Telomere lengths of translocation-associated and nontranslocation-associated sarcomas differ dramatically |
| Q36421126 | Telomere loops and homologous recombination-dependent telomeric circles in a Kluyveromyces lactis telomere mutant strain. |
| Q34988280 | Telomere maintenance and cancer -- look, no telomerase. |
| Q35544622 | Telomere maintenance and disease |
| Q34257327 | Telomere maintenance and telomerase activity are differentially regulated in asexual and sexual worms |
| Q39504471 | Telomere maintenance in Wilms tumors: first evidence for the presence of alternative lengthening of telomeres mechanism. |
| Q35800682 | Telomere maintenance in childhood primitive neuroectodermal brain tumors |
| Q24338140 | Telomere maintenance requires the RAD51D recombination/repair protein |
| Q24681584 | Telomere rapid deletion regulates telomere length in Arabidopsis thaliana |
| Q33474860 | Telomere recombination accelerates cellular aging in Saccharomyces cerevisiae |
| Q36761799 | Telomere regulation and function during meiosis |
| Q37445974 | Telomere-Internal Double-Strand Breaks Are Repaired by Homologous Recombination and PARP1/Lig3-Dependent End-Joining |
| Q35131777 | Telomere-driven genomic instability in cancer cells. |
| Q35062454 | Telomeres and cancer: a tale with many endings |
| Q29615353 | Telomeres and human disease: ageing, cancer and beyond |
| Q39413214 | Telomeres and telomerase in prostate cancer development and therapy. |
| Q36497017 | Telomeres and viruses: common themes of genome maintenance. |
| Q24678913 | Telomeres shorten more slowly in long-lived birds and mammals than in short-lived ones |
| Q48207441 | Telomeres: Implications for Cancer Development |
| Q28116259 | Telomeric D-loops containing 8-oxo-2'-deoxyguanosine are preferred substrates for Werner and Bloom syndrome helicases and are bound by POT1 |
| Q44732917 | Telomeric DNA damage by topoisomerase I. A possible mechanism for cell killing by camptothecin |
| Q33982700 | Telomeric DNA in ALT cells is characterized by free telomeric circles and heterogeneous t-loops |
| Q28508824 | Telomeric DNA mediates de novo PML body formation |
| Q37419279 | Telomeric armor: the layers of end protection |
| Q35170132 | Telomeric overhang length determines structural dynamics and accessibility to telomerase and ALT-associated proteins |
| Q33266104 | Tetrahymena POT1a regulates telomere length and prevents activation of a cell cycle checkpoint |
| Q39753325 | The Rad51 pathway of telomerase-independent maintenance of telomeres can amplify TG1-3 sequences in yku and cdc13 mutants of Saccharomyces cerevisiae. |
| Q28071562 | The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype |
| Q24313641 | The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins |
| Q40089362 | The Telomeric Response to Viral Infection |
| Q43955301 | The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: a multi-institutional study of 214 astrocytomas |
| Q43280142 | The alternative lengthening of telomeres phenotype in breast carcinoma is associated with HER-2 overexpression |
| Q41346379 | The human CTC1/STN1/TEN1 complex regulates telomere maintenance in ALT cancer cells |
| Q46772884 | The microarchitecture of DNA replication domains |
| Q42152999 | The regulation of telomerase in oncogenesis. |
| Q34931089 | The role of double-strand break repair pathways at functional and dysfunctional telomeres |
| Q36516357 | The role of telomere biology in bone marrow failure and other disorders |
| Q37132513 | The telomere-associated homeobox-containing protein TAH1/HMBOX1 participates in telomere maintenance in ALT cells |
| Q90744618 | Therapeutic Targets in Telomerase and Telomere Biology of Cancers |
| Q38937312 | Topoisomerase II inhibition suppresses the proliferation of telomerase-negative cancers. |
| Q38135137 | Translational research in endocrine surgery |
| Q38204883 | Tuning cell fate: from insights to vertebrate regeneration |
| Q34081803 | Twisted epithelial-to-mesenchymal transition promotes progression of surviving bladder cancer T24 cells with hTERT-dysfunction |
| Q40519654 | Two genetic variants in telomerase-associated protein 1 are associated with stomach cancer risk |
| Q34081730 | Two retrotransposons maintain telomeres in Drosophila |
| Q39915528 | Unusual telomeric DNAs in human telomerase-negative immortalized cells |
| Q35186715 | Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: osteosarcoma and related tumors |
| Q54546189 | Variation of telomerase activity and morphology in porcine mesenchymal stem cells and fibroblasts during prolonged in vitro culture. |
| Q34077917 | Visualization of telomerase reverse transcriptase (hTERT) promoter activity using a trimodality fusion reporter construct. |
| Q24634392 | Visualizing telomere dynamics in living mammalian cells using PNA probes |
| Q29036018 | Why are parasite contingency genes often associated with telomeres? |
| Q45722963 | hTERT rs2736098 genetic variants and susceptibility of hepatocellular carcinoma in the Chinese population: a case-control study |
| Q39474470 | p53 and p21(Waf1) Are Recruited to Distinct PML‐Containing Nuclear Foci in Irradiated and Nutlin‐3a‐Treated U2OS Cells |
| Q40544871 | p53 differentially inhibits cell growth depending on the mechanism of telomere maintenance |
| Q81110435 | t-Loops in yeast mitochondria |
Search more.