review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1177/107327480401100214 |
P698 | PubMed publication ID | 15024344 |
P2093 | author name string | Ngaire Elwood | |
P2860 | cites work | Tankyrase, a poly(ADP-ribose) polymerase at human telomeres | Q22008022 |
Mammalian telomeres end in a large duplex loop | Q22009893 | ||
Ku binds telomeric DNA in vitro | Q22010395 | ||
Normal human chromosomes have long G-rich telomeric overhangs at one end | Q22065787 | ||
Identification of human Rap1: implications for telomere evolution | Q22254239 | ||
Human POT1 facilitates telomere elongation by telomerase | Q24303687 | ||
A human telomeric protein | Q24304466 | ||
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization | Q24310670 | ||
Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2 | Q24317670 | ||
Control of telomere length by the human telomeric protein TRF1 | Q24320111 | ||
Extension of life-span by introduction of telomerase into normal human cells | Q24336088 | ||
The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats | Q24339608 | ||
Retinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiation | Q24596210 | ||
Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA. | Q27640301 | ||
Specific Association of Human Telomerase Activity with Immortal Cells and Cancer | Q27860801 | ||
Stem cells, cancer, and cancer stem cells | Q27860878 | ||
TRF2 Protects Human Telomeres from End-to-End Fusions | Q28111898 | ||
Stem Cells | Q28111899 | ||
Human Ku70/80 associates physically with telomerase through interaction with hTERT | Q28115815 | ||
Pot1, the putative telomere end-binding protein in fission yeast and humans | Q28188476 | ||
The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita | Q28189076 | ||
The RNA component of human telomerase | Q28288330 | ||
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts | Q28306745 | ||
Telomeric localization of TRF2, a novel human telobox protein | Q28314941 | ||
Senescence Induced by Altered Telomere State, Not Telomere Loss | Q28315731 | ||
p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2 | Q28609749 | ||
The serial cultivation of human diploid cell strains | Q29547356 | ||
Telomeres shorten during ageing of human fibroblasts | Q29547357 | ||
Telomerase catalytic subunit homologs from fission yeast and human | Q29615387 | ||
Switching and signaling at the telomere | Q29615653 | ||
A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes | Q29617061 | ||
Cell cycle checkpoint signaling through the ATM and ATR kinases | Q29617837 | ||
Essential role of mouse telomerase in highly proliferative organs | Q29620451 | ||
Early hematopoietic reconstitution after clinical stem cell transplantation: evidence for stochastic stem cell behavior and limited acceleration in telomere loss | Q33183485 | ||
Differentiation of immortal cells inhibits telomerase activity. | Q33670557 | ||
In vivo telomere dynamics of human hematopoietic stem cells | Q33726870 | ||
p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis | Q33862956 | ||
Telomerase activity in normal and malignant hematopoietic cells | Q33883794 | ||
The terminal DNA structure of mammalian chromosomes | Q33886897 | ||
Cell senescence and cancer | Q33957948 | ||
Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics | Q33962085 | ||
The telomere hypothesis of cellular aging | Q33973605 | ||
The role of telomerase expression and telomere length maintenance in human and mouse | Q34001044 | ||
Repair of telomeric DNA prior to replicative senescence | Q34034005 | ||
Alternative lengthening of telomeres in mammalian cells | Q34114656 | ||
Telomerase activation, cellular immortalization and cancer | Q34235187 | ||
Telomere dynamics and genetic instability in disease progression of chronic myeloid leukemia | Q34293533 | ||
Telomere maintenance mechanisms as a target for drug development | Q34293590 | ||
Telomere dynamics in myelodysplastic syndromes and acute leukemic transformation | Q34431569 | ||
Very short telomeres in the peripheral blood of patients with X-linked and autosomal dyskeratosis congenita | Q34514264 | ||
Telomerase in the human organism | Q34535632 | ||
Senescence: does it all happen at the ends? | Q34535679 | ||
Telomeres and telomerase in hematologic neoplasia | Q34535734 | ||
Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age. | Q34724924 | ||
Telomere shortening in hematopoietic stem cell transplantation: a potential mechanism for late graft failure? | Q35015447 | ||
Stem cells, telomerase and dyskeratosis congenita | Q35050092 | ||
Hematopoietic stem cells and hematopoiesis | Q35071092 | ||
It's moving day: factors affecting peripheral blood stem cell mobilization and strategies for improvement [corrected]. | Q35183791 | ||
Telomeric DNA in normal and leukemic blood cells | Q35553065 | ||
The rate of telomere sequence loss in human leukocytes varies with age. | Q36093340 | ||
Regulated expression of telomerase activity in human T lymphocyte development and activation | Q36366852 | ||
Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood. | Q36375132 | ||
Regulation of telomerase activity in immortal cell lines | Q36560197 | ||
Telomere loss: mitotic clock or genetic time bomb? | Q36706939 | ||
An overhanging 3' terminus is a conserved feature of telomeres | Q36753674 | ||
Cell cycle-dependent modulation of telomerase activity in tumor cells. | Q37573521 | ||
Heterogeneity in telomere length of human chromosomes. | Q39426746 | ||
Telomerase, Cell Immortality, and Cancer | Q40431193 | ||
Telomerase inhibition with an oligonucleotide telomerase template antagonist: in vitro and in vivo studies in multiple myeloma and lymphoma | Q40635344 | ||
Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype | Q40978432 | ||
Dimethyl sulfoxide (DMSO) causes a reversible inhibition of telomerase activity in a Burkitt lymphoma cell line. | Q41022028 | ||
Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase | Q41053498 | ||
Absence of p53 allows direct immortalization of hematopoietic cells by the myc and raf oncogenes | Q41326041 | ||
Human endothelial cell life extension by telomerase expression | Q41688544 | ||
Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow | Q42528725 | ||
Telomere length changes in patients with aplastic anaemia | Q43572280 | ||
Normalization of previously shortened telomere length under treatment with imatinib argues against a preexisting telomere length deficit in normal hematopoietic stem cells from patients with chronic myeloid leukemia | Q44473593 | ||
Telomerase activity in hematopoietic cells is associated with self-renewal potential | Q46183315 | ||
Telomere states and cell fates | Q46830116 | ||
Telomere shortening is proportional to the size of the G-rich telomeric 3'-overhang | Q47240761 | ||
Down-regulation of telomerase activity is an early event of cellular differentiation without apparent telomeric DNA change | Q47783344 | ||
Severe growth defect in mouse cells lacking the telomerase RNA component | Q47991784 | ||
Expression of TERT in early premalignant lesions and a subset of cells in normal tissues | Q47991825 | ||
Accelerated telomere shortening in young recipients of allogeneic bone-marrow transplants. | Q50910580 | ||
Accelerated telomere shortening in hematological lineages is limited to the first year following stem cell transplantation. | Q52022148 | ||
Telomere dynamics in childhood leukemia and solid tumors: a follow-up study. | Q52109001 | ||
Mass cultured human fibroblasts overexpressing hTERT encounter a growth crisis following an extended period of proliferation. | Q52165691 | ||
Telomerase activity and telomere length in pediatric patients with malignancies undergoing chemotherapy. | Q52191382 | ||
Telomerase maintains telomere structure in normal human cells. | Q52551445 | ||
Telomerase activity and cytogenetic changes in chronic myeloid leukemia with disease progression. | Q53446477 | ||
Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry. | Q55067752 | ||
The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability | Q56508014 | ||
Tankyrase promotes telomere elongation in human cells | Q56969704 | ||
P433 | issue | 2 | |
P304 | page(s) | 77-85 | |
P577 | publication date | 2004-03-01 | |
P1433 | published in | Cancer Control | Q15724614 |
P1476 | title | Telomere biology of human hematopoietic stem cells | |
P478 | volume | 11 |
Q40470548 | Acute myeloid leukemia arising from a donor derived premalignant hematopoietic clone: A possible mechanism for the origin of leukemia in donor cells. |
Q41990866 | Effects of water, sanitation, handwashing, and nutritional interventions on telomere length among children in a cluster-randomized controlled trial in rural Bangladesh |
Q81073576 | Functional genomics of hTERT gene in leukemic myelopoiesis |
Q40284074 | Human telomerase reverse transcriptase protects hematopoietic progenitor TF-1 cells from death and quiescence induced by cytokine withdrawal |
Q36274746 | Postnatal stem cell survival: does the niche, a rare harbor where to resist the ebb tide of differentiation, also provide lineage-specific instructions? |
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